Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Matteo Morotti"'
Autor:
Giulia Spagnol, Eleonora Ghisoni, Matteo Morotti, Orazio De Tommasi, Matteo Marchetti, Sofia Bigardi, Valentina Tuninetti, Giulia Tasca, Marco Noventa, Carlo Saccardi, Roberto Tozzi, Denarda Dangaj Laniti
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 13, p 7070 (2024)
Immunotherapy, particularly the use of immune checkpoint inhibitors (ICIs), has shown limited efficacy in treating ovarian cancer (OC), possibly due to diverse T cell infiltration patterns in the tumor microenvironment. This review explores how neoad
Externí odkaz:
https://doaj.org/article/08783547fdaa4b2b95d755c900210f3e
Autor:
Abdulkhaliq Alsaadi, Mara Artibani, Zhiyuan Hu, Nina Wietek, Matteo Morotti, Laura Santana Gonzalez, Moiad Alazzam, Jason Jiang, Beena Abdul, Hooman Soleymani majd, Levi L. Blazer, Jarret Adams, Francesca Silvestri, Sachdev S. Sidhu, Joan S. Brugge, Ahmed Ashour Ahmed
Publikováno v:
Cell Reports, Vol 42, Iss 11, Pp 113354- (2023)
Summary: The study of fallopian tube (FT) function in health and disease has been hampered by limited knowledge of FT stem cells and lack of in vitro models of stem cell renewal and differentiation. Using optimized organoid culture conditions to addr
Externí odkaz:
https://doaj.org/article/b3b9c8430ef84ea8bc3a229beaff06ed
Autor:
Manuela Eicher, Massimo Di Maio, George Coukos, Lionel Trueb, Matteo Morotti, Eleonora Ghisoni, Sara Colomer-Lahiguera
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 12 (2022)
Adoptive cell therapies (ACT) have demonstrated promise in the treatment of patients with cancer, leading to long-lasting responses and, in some cases, even cure. Technological advances have brought these individualized therapies closer to reality, e
Externí odkaz:
https://doaj.org/article/9e517d74a1674ea6840acf0cdd210cbf
Autor:
Ciro Pinelli, Matteo Morotti, Jvan Casarin, Roberto Tozzi, Moiad Alazzam, Vasileios K. Mavroeidis, Hooman Soleymani majd
Publikováno v:
Journal of Investigative Surgery, Vol 34, Iss 7, Pp 756-762 (2021)
Background Several studies have demonstrated the feasibility and role of bulky cardiophrenic lymph nodes (CPLNs) resection during primary debulking surgery (PDS) for stage IV ovarian cancer (OC). However, no studies, to date, investigated the accurac
Externí odkaz:
https://doaj.org/article/79d3c746942949b5b670beaab5ad2da9
Autor:
Ciro Pinelli, Matteo Morotti, Jvan Casarin, Roberto Tozzi, Fabio Ghezzi, Vasileios K. Mavroeidis, Moiad Alazzam, Hooman Soleymani majd
Publikováno v:
Journal of Investigative Surgery, Vol 34, Iss 9, Pp 1023-1030 (2021)
Background Elderly ovarian cancer (OC) patients are more likely to be managed suboptimally, with worse clinical outcomes as a result. Strategies to decrease morbidity are lacking. Methodology: Consecutive patients with advanced stage OC (IIIC-IV) who
Externí odkaz:
https://doaj.org/article/4a35d942639f4c61ab7db3f3fa27a27a
Publikováno v:
Gynecologic Oncology Reports, Vol 37, Iss , Pp 100807- (2021)
Surgery in advanced ovarian malignancy is indicated when complete debulking can be achieved. In patients with disease above the diaphragm, achieving R0 can present a surgical challenge and bring into question the feasibility of surgery (Soleymani maj
Externí odkaz:
https://doaj.org/article/14bee203a1c746c180cbb7794883092c
Autor:
Mara Artibani, Kenta Masuda, Zhiyuan Hu, Pascal C. Rauher, Garry Mallett, Nina Wietek, Matteo Morotti, Kay Chong, Mohammad KaramiNejadRanjbar, Christos E. Zois, Sunanda Dhar, Salma El-Sahhar, Leticia Campo, Sarah P. Blagden, Stephen Damato, Pubudu N. Pathiraja, Shibani Nicum, Fergus Gleeson, Alexandros Laios, Abdulkhaliq Alsaadi, Laura Santana Gonzalez, Takeshi Motohara, Ashwag Albukhari, Zhen Lu, Robert C. Bast Jr., Adrian L. Harris, Christer S. Ejsing, Robin W. Klemm, Christopher Yau, Tatjana Sauka-Spengler, Ahmed Ashour Ahmed
Publikováno v:
JCI Insight, Vol 6, Iss 11 (2021)
Similar to tumor-initiating cells (TICs), minimal residual disease (MRD) is capable of reinitiating tumors and causing recurrence. However, the molecular characteristics of solid tumor MRD cells and drivers of their survival have remained elusive. He
Externí odkaz:
https://doaj.org/article/aed4f3377d6c477db1f5a1a0d72b84ea
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 13 (2021)
Epithelial ovarian cancer (EOC) is the most important cause of gynecological cancer-related mortality. Despite improvements in medical therapies, particularly with the incorporation of drugs targeting homologous recombination deficiency, EOC survival
Externí odkaz:
https://doaj.org/article/01c32a9b391f4b55a554c47bffae7a71
Autor:
Laura Santana Gonzalez, Ioanna A. Rota, Mara Artibani, Matteo Morotti, Zhiyuan Hu, Nina Wietek, Abdulkhaliq Alsaadi, Ashwag Albukhari, Tatjana Sauka-Spengler, Ahmed A. Ahmed
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
The conduits of life; the animal oviducts and human fallopian tubes are of paramount importance for reproduction in amniotes. They connect the ovary with the uterus and are essential for fertility. They provide the appropriate environment for gamete
Externí odkaz:
https://doaj.org/article/912f155ee14e44c5989f20449aab2a56
Autor:
Matteo Tantari, Stefano Bogliolo, Matteo Morotti, Vincent Balaya, Florent Bouttitie, Annie Buenerd, Laurent Magaud, Fabrice Lecuru, Benedetta Guani, Patrice Mathevet, on behalf of the SENTICOL Group
Publikováno v:
Cancers, Vol 14, Iss 1, p 212 (2022)
Background: In patients with cervical cancer, the presence of tumoral lymph-vascular space invasion (LVSI) is the main risk factor for pelvic lymph node metastasis (PLNM). The objective of this study was to evaluate the presence of several markers of
Externí odkaz:
https://doaj.org/article/301f786605a24c27b95959ea8e1c6fd9