Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Matteo Marco Longhi"'
Autor:
Lorenza Pirona, Roberto Dilernia, Valerio Tazzari, Carlo De Toma, Anna Elisa Valsecchi, Sergio Menegon, Silvia Caligari, Matteo Marco Longhi, Fabio Frigerio, Giulio Vistoli, Giulio Rastelli, Davide Graziani, Elisa Callegari, Luca Pinzi, Carlo Riva
Publikováno v:
Journal of medicinal chemistry. 62(3)
Negative allosteric modulators (NAMs) of the metabotropic glutamate receptor 5 (mGlu5) hold great promise for the treatment of a variety of central nervous system disorders. We have recently reported that prop-2-ynylidenecycloalkylamine derivatives a
Autor:
Antonio Cilia, Ilaria Bettinelli, Andrew Anighoro, Lorenza Pirona, Fabio Mangiarotti, Sergio Menegon, Carlo Riva, Elena Poggesi, Carlo De Toma, Giulio Rastelli, Matteo Marco Longhi, Davide Graziani
Publikováno v:
Bioorganicmedicinal chemistry. 23(13)
Metabotropic glutamate receptor 5 (mGlu 5 ) is a biological target implicated in major neurological and psychiatric disorders. In the present study, we have investigated structural determinants of the interaction of negative allosteric modulators (NA