TREM-1 promotes intestinal tumorigenesis

Autor: Leslie Saurer, Daniel Zysset, Christoph Mueller, Philippe Krebs, Silvia Rihs, Cedric Simillion, Inti Zlobec, Matteo Gusberti, Lukas F. Mager, Alessandro Lugli

Publikováno v: Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Scientific Reports
Saurer, Leslie; Zysset, Daniel; Rihs, Silvia; Mager, Lukas; Gusberti, Matteo; Simillion, Cedric; Lugli, Alessandro; Zlobec, Inti; Krebs, Philippe; Müller, Christoph (2017). TREM-1 promotes intestinal tumorigenesis. Scientific Reports, 7(1), p. 14870. Nature Publishing Group 10.1038/s41598-017-14516-4

Triggering receptor expressed on myeloid cells-1 (TREM-1) is a potent amplifier of pro-inflammatory innate immune responses. Increasing evidence suggests a role for TREM-1 not only in acute pathogen-induced reactions but also in chronic and non-infec

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http://link.springer.com/article/10.1038/s41598-017-14516-4