Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Matteo E, Mangoni"'
Autor:
Zeyuan Yin, Eleonora Torre, Manon Marrot, Colin H. Peters, Amy Feather, William G. Nichols, Sunil Jit R. J. Logantha, Areej Arshad, Simran Agnes Martis, Nilay Tugba Ozturk, Weixuan Chen, Jiaxuan Liu, Jingmo Qu, Min Zi, Elizabeth J. Cartwright, Catherine Proenza, Angelo Torrente, Matteo E. Mangoni, Halina Dobrzynski, Andrew J. Atkinson
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
BackgroundThe sinoatrial node (SN) generates the heart rate (HR). Its spontaneous activity is regulated by a complex interplay between the modulation by the autonomic nervous system (ANS) and intrinsic factors including ion channels in SN cells. Howe
Externí odkaz:
https://doaj.org/article/c4c21de8b7b44bc582fd73e768507905
Autor:
Manon Marrot, Yasmine Colombani, Joel Cuoq, Pascaline Fontes, Faustine Hugon, Stéphanie Barrere-Lemaire, Nadine Mestre-Frances, Matteo E. Mangoni, Angelo Torrente
Publikováno v:
Journal of Molecular and Cellular Cardiology Plus, Vol 10, Iss , Pp 100098- (2024)
Externí odkaz:
https://doaj.org/article/3334f41407ea4a7e98dfcc9a7ccd8e60
Autor:
Pietro Mesirca, Jean Chemin, Christian Barrère, Eleonora Torre, Laura Gallot, Arnaud Monteil, Isabelle Bidaud, Sylvie Diochot, Michel Lazdunski, Tuck Wah Soong, Stéphanie Barrère-Lemaire, Matteo E. Mangoni, Joël Nargeot
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract L-type voltage-gated calcium channels are involved in multiple physiological functions. Currently available antagonists do not discriminate between L-type channel isoforms. Importantly, no selective blocker is available to dissect the role o
Externí odkaz:
https://doaj.org/article/2ab832a282b64fedbaeb690c44acc317
Autor:
Mattia L. DiFrancesco, Manon Marrot, Eleonora Torre, Pietro Mesirca, Romain Davaze, Corinne Lautier, Pascaline Fontes, Joël Cuoq, Anne Fernandez, Ned Lamb, Fabien Pifferi, Nadine Mestre-Francés, Matteo E. Mangoni, Angelo G. Torrente
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Microcebus murinus, or gray mouse lemur (GML), is one of the smallest primates known, with a size in between mice and rats. The small size, genetic proximity to humans and prolonged senescence, make this lemur an emerging model for neurodege
Externí odkaz:
https://doaj.org/article/252330b0209f428c86ff38f1c8a27303
Autor:
Daniel Turner, Chen Kang, Pietro Mesirca, Juan Hong, Matteo E. Mangoni, Alexey V. Glukhov, Rajan Sah
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
The understanding of the electrophysiological mechanisms that underlie mechanosensitivity of the sinoatrial node (SAN), the primary pacemaker of the heart, has been evolving over the past century. The heart is constantly exposed to a dynamic mechanic
Externí odkaz:
https://doaj.org/article/7ab8744d7c2b453c85ae5fe7ecfac9a0
Autor:
Michael J. Wallace, Mona El Refaey, Pietro Mesirca, Thomas J. Hund, Matteo E. Mangoni, Peter J. Mohler
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
The pacemaker cells of the cardiac sinoatrial node (SAN) are essential for normal cardiac automaticity. Dysfunction in cardiac pacemaking results in human sinoatrial node dysfunction (SND). SND more generally occurs in the elderly population and is a
Externí odkaz:
https://doaj.org/article/12565219d0e44d409486f3ab9e98b4b4
Autor:
Isabelle Bidaud, Alicia D’Souza, Gabriella Forte, Eleonora Torre, Denis Greuet, Steeve Thirard, Cali Anderson, Antony Chung You Chong, Angelo G. Torrente, Julien Roussel, Kevin Wickman, Mark R. Boyett, Matteo E. Mangoni, Pietro Mesirca
Publikováno v:
Frontiers in Physiology, Vol 11 (2021)
Background: Endurance athletes are prone to bradyarrhythmias, which in the long-term may underscore the increased incidence of pacemaker implantation reported in this population. Our previous work in rodent models has shown training-induced sinus bra
Externí odkaz:
https://doaj.org/article/2cc2c4e30f3345eab7d6fbf48727ec24
Autor:
Julien Louradour, Olivier Bortolotti, Eleonora Torre, Isabelle Bidaud, Ned Lamb, Anne Fernandez, Jean-Yves Le Guennec, Matteo E. Mangoni, Pietro Mesirca
Publikováno v:
Cells, Vol 11, Iss 7, p 1114 (2022)
Background: Sinoatrial node cells (SANC) automaticity is generated by functional association between the activity of plasmalemmal ion channels and local diastolic intracellular Ca2+ release (LCR) from ryanodine receptors. Strikingly, most isolated SA
Externí odkaz:
https://doaj.org/article/ca195c330f954913ae0c00fe4716a237
Autor:
Futoshi Toyoda, Pietro Mesirca, Stefan Dubel, Wei-Guang Ding, Joerg Striessnig, Matteo E. Mangoni, Hiroshi Matsuura
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract The spontaneous activity of sinoatrial node (SAN) pacemaker cells is generated by a functional interplay between the activity of ionic currents of the plasma membrane and intracellular Ca2+ dynamics. The molecular correlate of a dihydropyrid
Externí odkaz:
https://doaj.org/article/31da581eaaa3446c8c655c6a488ae13e
Autor:
Jérôme Montnach, Hugo Millet, Antoine Persello, Hervé Meudal, Stephan De Waard, Pietro Mesrica, Barbara Ribeiro, Jérémie Richard, Agnès Hivonnait, Agnès Tessier, Benjamin Lauzier, Flavien Charpentier, Matteo E. Mangoni, Céline Landon, Chris Jopling, Michel De Waard
RATIONALECardiac rhythm, conduction and synchronization of electrical activity require the coordinated action of different types of ion channels that differ according to transmural and regional specificities. Classical pharmacology affects these ion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::036527a695c4da772fea17a8012bb815
https://doi.org/10.1101/2023.03.23.534038
https://doi.org/10.1101/2023.03.23.534038
