Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Matteo Cabrini"'
Autor:
Ilaria Rosso, Corey Jones-Weinert, Francesca Rossiello, Matteo Cabrini, Silvia Brambillasca, Leonel Munoz-Sagredo, Zeno Lavagnino, Emanuele Martini, Enzo Tedone, Massimiliano Garre’, Julio Aguado, Dario Parazzoli, Marina Mione, Jerry W. Shay, Ciro Mercurio, Fabrizio d’Adda di Fagagna
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Alternative lengthening of telomeres (ALT) is a telomere maintenance mechanism activated in ~10–15% of cancers, characterized by telomeric damage. Telomeric damage-induced long non-coding RNAs (dilncRNAs) are transcribed at dysfunctional t
Externí odkaz:
https://doaj.org/article/96aecb24e77f4ab3b16b729a382e090c
Autor:
Fabio Iannelli, Alessandro Galbiati, Ilaria Capozzo, Quan Nguyen, Brian Magnuson, Flavia Michelini, Giuseppina D’Alessandro, Matteo Cabrini, Marco Roncador, Sofia Francia, Nicola Crosetto, Mats Ljungman, Piero Carninci, Fabrizio d’Adda di Fagagna
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
DNA double strand breaks (DSBs) are among the most deleterious types of damage and there is strong evidence indicating a relationship between breaks and transcription. Here the authors provide a high-resolution, genome-wide map of induced DSBs and ob
Externí odkaz:
https://doaj.org/article/a4cc05be64fb4756ab65972047e8495b
Autor:
Ubaldo Gioia, Sara Tavella, Pamela Martínez-Orellana, Giada Cicio, Andrea Colliva, Marta Ceccon, Matteo Cabrini, Ana C. Henriques, Valeria Fumagalli, Alessia Paldino, Ettore Presot, Sreejith Rajasekharan, Nicola Iacomino, Federica Pisati, Valentina Matti, Sara Sepe, Matilde I. Conte, Sara Barozzi, Zeno Lavagnino, Tea Carletti, Maria Concetta Volpe, Paola Cavalcante, Matteo Iannacone, Chiara Rampazzo, Rossana Bussani, Claudio Tripodo, Serena Zacchigna, Alessandro Marcello, Fabrizio d’Adda di Fagagna
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the RNA virus responsible for the coronavirus disease 2019 (COVID-19) pandemic. Although SARS-CoV-2 was reported to alter several cellular pathways, its impact on DNA integrity and the m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02232d4a62e92cbb07c5c2990aa00db5
https://hdl.handle.net/11577/3471427
https://hdl.handle.net/11577/3471427
Autor:
Matteo Cabrini, Fabio Iannelli, Jerry W. Shay, Francesca Rossiello, Giada Cicio, Arianna Di Napoli, Sara Sepe, Valentina Matti, Valeria Cancila, Alessia di Lillo, Busola R. Alabi, Fabrizio d'Adda di Fagagna, Eugenia Marinelli, Claudio Tripodo
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes the coronavirus disease 2019 (COVID-19), known to be more common in the elderly, who also show more severe symptoms and are at higher risk of hospitalization and death. Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17bc583062123e21bd3abf38344040c3
http://hdl.handle.net/10447/532003
http://hdl.handle.net/10447/532003
Autor:
Matteo Cabrini, Fabrizio d'Adda di Fagagna, Sofia Francia, Ubaldo Gioia, Silvia Brambillasca, Corey Winston Jones-Weinert, Flavia Michelini
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-15 (2019)
A novel class of small non-coding RNAs called DNA damage response RNAs (DDRNAs) generated at DNA double-strand breaks (DSBs) in a DROSHA- and DICER-dependent manner has been shown to regulate the DNA damage response (DDR). Similar molecules were also
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::942f58e4fd8b2ce2c65e8b2ab87512c5
http://link.springer.com/article/10.1038/s41598-019-42892-6
http://link.springer.com/article/10.1038/s41598-019-42892-6
Autor:
Fabrizio d'Adda di Fagagna, Sofia Francia, Antonio Maffia, Lina Cipolla, Simone Sabbioneda, Matteo Cabrini, Fabio Iannelli, Alessandro Galbiati, Marco Roncador
Publikováno v:
Journal of Cell Science
article-version (VoR) Version of Record
article-version (VoR) Version of Record
The DNA damage response (DDR) is the signaling cascade that recognizes DNA double-strand breaks (DSBs) and promotes their resolution via the DNA repair pathways of non-homologous end joining (NHEJ) or homologous recombination (HR). We and others have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b44717b661cc59422e28ed1b26f09a5
https://www.zora.uzh.ch/id/eprint/207429/
https://www.zora.uzh.ch/id/eprint/207429/
Autor:
Sofia Francia, Alessandro Galbiati, Lina Cipolla, Matteo Cabrini, Fabio Iannelli, Fabrizio d'Adda di Fagagna, Simone Sabbioneda, Marco Roncador
The DNA damage response (DDR) is the signaling cascade through which a cell recognizes DNA lesions, and promotes their resolution via the repair pathways of Non-Homologous End Joining (NHEJ), or Homologous Recombination (HR). We recently demonstrated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47bed249f457520d682b279e57a38e00
Autor:
Fabrizio d'Adda di Fagagna, Nils G. Walter, Yejun Wang, Fabio Pessina, Valentina Matti, Ubaldo Gioia, G. V. Shivashankar, Sofia Francia, Ilaria Capozzo, Matteo Cabrini, Fabio Iannelli, Sheetal Sharma, Sethuramasundaram Pitchiaya, Valerio Vitelli, Flavia Michelini
Publikováno v:
Nature cell biology
The DNA damage response (DDR) preserves genomic integrity. Small non-coding RNAs termed DDRNAs are generated at DNA double-strand breaks (DSBs) and are critical for DDR activation. Here we show that active DDRNAs specifically localize to their damage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7581ec181bd9ee22fa12b8ef13d37dbf
https://pubmed.ncbi.nlm.nih.gov/29180822
https://pubmed.ncbi.nlm.nih.gov/29180822
Autor:
Quan Nguyen, Brian Magnuson, Nicola Crosetto, Flavia Michelini, Matteo Cabrini, Fabio Iannelli, Ilaria Capozzo, Giuseppina D'Alessandro, Marco Roncador, Piero Carninci, Sofia Francia, Alessandro Galbiati, Mats Ljungman, Fabrizio d'Adda di Fagagna
Publikováno v:
Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Of the many types of DNA damage, DNA double-strand breaks (DSBs) are probably the most deleterious. Mounting evidence points to an intricate relationship between DSBs and transcription. A cell system in which the impact on transcription can be invest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::345605f965efe3e05e13e1d46376105f
https://doi.org/10.1038/ncomms15656
https://doi.org/10.1038/ncomms15656
Publikováno v:
Journal of Cell Science
The DNA damage response (DDR) plays a central role in preserving genome integrity. Recently, we reported that the endoribonucleases DICER and DROSHA contribute to DDR activation by generating small non-coding RNAs, termed DNA damage response RNA (DDR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74cdb6c8b0d1ada3a6925a1a45a66522
https://doi.org/10.1242/jcs.182188
https://doi.org/10.1242/jcs.182188