Coexpression of ΔNp63/p40 and TTF1 Within Most of the Same Individual Cells Identifies Life-Threatening NSCLC Featuring Squamous and Glandular Biphenotypic Differentiation: Clinicopathologic Correlations

Autor: Giuseppe Pelosi, MD, MIAC, Matteo Bulloni, PhD, Martina Vescio, PhD, Silvia Uccella, MD, Fabien Forest, MD, Giorgia Leone, MD, Massimo Barberis, MD, Daoud Rahal, MD, Paola Bossi, MD, Giovanna Finzi, MD, Deborah Marchiori, MD, Marco De Luca, MD, Fausto Sessa, MD, Sergio Harari, MD, Manuela Spinelli, MD, Patrizia Viola, MD, Paolo Macrì, MD, Stefania Maria, MD, Antonio Rizzo, MD, Antonio Picone, MD, Linda Pattini, PhD

Publikováno v: JTO Clinical and Research Reports, Vol 2, Iss 11, Pp 100222- (2021)

Introduction: Double occurrence of TTF1 and ΔNp63/p40 (henceforth, p40) within the same individual cells is exceedingly rare in lung cancer. Little is known on their biological and clinical implications. Methods: Two index cases immunoreactive for b

Externí odkaz: https://doaj.org/article/b5599054993748b39c6aa8019d597ff7

Automated Analysis of Proliferating Cells Spatial Organisation Predicts Prognosis in Lung Neuroendocrine Neoplasms

Autor: Valeria Maffeis, Lina Carvalho, Giuseppe Pelosi, Deborah Marchiori, Fiorella Calabrese, Véronique Hofman, Gabriella Nesi, Myriam Remmelink, Fausto Sessa, Irene Stacchiotti, Angela De Palma, Salma Naheed, Jasna Metovic, Linda Pattini, Giuseppe Marulli, Silvia Uccella, Christian H. Ottensmeier, Giada Sandrini, Federico Rea, Gabriella Serio, Izidor Kern, Roberta Maragliano, Paul Hofman, Massimo Barberis, Eugenio Maiorano, Matteo Bulloni, Antonio Pennella, Ambrogio Fassina, Gabriella Fontanini, Federica Pezzuto, Mauro Papotti, Francesco Fortarezza, Eleonora Pisa, Senia Trabucco, Andrea Marzullo, Greta Alì

Publikováno v: Cancers, Vol 13, Iss 4875, p 4875 (2021)
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Cancers
Volume 13
Issue 19
Cancers, vol. 13, no. 19, pp. 1-19, 2021.
Cancers (Basel), 13 (19
CANCERS

Lung neuroendocrine neoplasms (lung NENs) are categorised by morphology, defining a classification sometimes unable to reflect ultimate clinical outcome. Subjectivity and poor reproducibility characterise diagnosis and prognosis assessment of all NEN

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98359bf55accb40bcdbb21543602d7c1
https://www.mdpi.com/2072-6694/13/19/4875