Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Matteo Broketa"'
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
Droplet-based microfluidics techniques coupled to microscopy allow for the characterization of cells at the single-cell scale. However, such techniques generate substantial amounts of data and microscopy images that must be analyzed. Droplets on thes
Externí odkaz:
https://doaj.org/article/7ea0d36dba4a4d17bc1a5c4381407a3e
Autor:
Matteo Broketa, Aurélien Sokal, Michael Mor, Pablo Canales-Herrerias, Angga Perima, Annalisa Meola, Ignacio Fernández, Bruno Iannascoli, Guilhem Chenon, Alexis Vandenberghe, Laetitia Languille, Marc Michel, Bertrand Godeau, Sébastien Gallien, Giovanna Melica, Marija Backovic, Felix A. Rey, Jean Baudry, Natalia T. Freund, Matthieu Mahévas, Pierre Bruhns
Publikováno v:
JCI Insight, Vol 8, Iss 13 (2023)
SARS-CoV-2 mRNA vaccination generates protective B cell responses targeting the SARS-CoV-2 spike glycoprotein. Whereas anti-spike memory B cell responses are long lasting, the anti-spike humoral antibody response progressively wanes, making booster v
Externí odkaz:
https://doaj.org/article/7231211eeec64200bc51bc6db3b32475
Autor:
Pablo Canales-Herrerias, Etienne Crickx, Matteo Broketa, Aurélien Sokal, Guilhem Chenon, Imane Azzaoui, Alexis Vandenberghe, Angga Perima, Bruno Iannascoli, Odile Richard-Le Goff, Carlos Castrillon, Guillaume Mottet, Delphine Sterlin, Ailsa Robbins, Marc Michel, Patrick England, Gael A. Millot, Klaus Eyer, Jean Baudry, Matthieu Mahevas, Pierre Bruhns
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 12 (2022)
The major therapeutic goal for immune thrombocytopenic purpura (ITP) is to restore normal platelet counts using drugs to promote platelet production or by interfering with mechanisms responsible for platelet destruction. Eighty percent of patients wi
Externí odkaz:
https://doaj.org/article/61a4750385984473a1abf8b9527e230a
Autor:
Matteo Broketa, Pierre Bruhns
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
Antibody-secreting cells (ASC), plasmablasts and plasma cells, are terminally differentiated B cells responsible for large-scale production and secretion of antibodies. ASC are derived from activated B cells, which may differentiate extrafollicularly
Externí odkaz:
https://doaj.org/article/3e762299d8d84b90adb247ebdfd8946b
Autor:
Jennifer Cable, Erica Ollmann Saphire, Adrian C. Hayday, Timothy D. Wiltshire, Jarrod J. Mousa, David P. Humphreys, Esther C. W. Breij, Pierre Bruhns, Matteo Broketa, Genta Furuya, Blake M. Hauser, Matthieu Mahévas, Andrea Carfi, Tineke Cantaert, Peter D. Kwong, Prabhanshu Tripathi, Jonathan H. Davis, Neil Brewis, Bruce A. Keyt, Felix L. Fennemann, Vincent Dussupt, Arvind Sivasubramanian, Philip M. Kim, Reda Rawi, Eve Richardson, Daniel Leventhal, Rachael M. Wolters, Cecile A. W. Geuijen, Matthew A. Sleeman, Niccolo Pengo, Francesca Rose Donnellan
Publikováno v:
Annals of the New York Academy of Sciences. 1519:153-166
Therapeutic antibodies have broad indications across diverse disease states, such as oncology, autoimmune diseases, and infectious diseases. New research continues to identify antibodies with therapeutic potential as well as methods to improve upon e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::351a2f61d632111c45e1bd85b269f42a
https://doi.org/10.1111/nyas.14915
https://doi.org/10.1111/nyas.14915
Autor:
Aurélien Sokal, Matteo Broketa, Giovanna Barba-Spaeth, Annalisa Meola, Ignacio Fernández, Slim Fourati, Imane Azzaoui, Andrea de La Selle, Alexis Vandenberghe, Anais Roeser, Magali Bouvier-Alias, Etienne Crickx, Laetitia Languille, Marc Michel, Bertrand Godeau, Sébastien Gallien, Giovanna Melica, Yann Nguyen, Virginie Zarrouk, Florence Canoui-Poitrine, France Noizat-Pirenne, Jérôme Megret, Jean-Michel Pawlotsky, Simon Fillatreau, Etienne Simon-Lorière, Jean-Claude Weill, Claude-Agnès Reynaud, Félix A. Rey, Pierre Bruhns, Pascal Chappert, Matthieu Mahévas
Publikováno v:
Immunity
Immunity, Elsevier, In press, ⟨10.1016/j.immuni.2022.04.002⟩
Immunity, 2022, 55 (6), pp.1096-1104.e4. ⟨10.1016/j.immuni.2022.04.002⟩
Immunity, Elsevier, In press, ⟨10.1016/j.immuni.2022.04.002⟩
Immunity, 2022, 55 (6), pp.1096-1104.e4. ⟨10.1016/j.immuni.2022.04.002⟩
International audience; The SARS-CoV-2 Omicron variant can escape neutralization by vaccine-elicited and convalescent antibodies. Memory B cells (MBCs) represent another layer of protection against SARS-CoV-2, as they persist after infection and vacc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f79edd55453451c697a1469c536ca195
https://hal.archives-ouvertes.fr/hal-03652602/file/1-s2.0-S107476132200173X-main.pdf
https://hal.archives-ouvertes.fr/hal-03652602/file/1-s2.0-S107476132200173X-main.pdf
Autor:
Aurélien Sokal, Matteo Broketa, Annalisa Meola, Giovanna Barba-Spaeth, Ignacio Fernández, Slim Fourati, Imane Azzaoui, Andrea de La Selle, Alexis Vandenberghe, Anais Roeser, Magali Bouvier-Alias, Etienne Crickx, Laetitia Languille, Marc Michel, Bertrand Godeau, Sébastien Gallien, Giovanna Melica, Yann Nguyen, Virginie Zarrouk, Florence Canoui-Poitrine, France Noizat-Pirenne, Jérôme Megret, Jean-Michel Pawlotsky, Simon Fillatreau, Etienne Simon-Lorière, Jean-Claude Weill, Claude-Agnès Reynaud, Félix A. Rey, Pierre Bruhns, Pascal Chappert, Matthieu Mahévas
SummaryMemory B cells (MBCs) represent a second layer of immune protection against SARS-CoV-2. Whether MBCs elicited by mRNA vaccines can recognize the Omicron variant is of major concern. We used bio-layer interferometry to assess the affinity again
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::038bc7ebc364a404cc63d04e0ae01acc
https://doi.org/10.1101/2021.12.21.473528
https://doi.org/10.1101/2021.12.21.473528
Autor:
Aurélien Sokal, Giovanna Barba-Spaeth, Ignacio Fernández, Matteo Broketa, Imane Azzaoui, Andréa de La Selle, Alexis Vandenberghe, Slim Fourati, Anais Roeser, Annalisa Meola, Magali Bouvier-Alias, Etienne Crickx, Laetitia Languille, Marc Michel, Bertrand Godeau, Sébastien Gallien, Giovanna Melica, Yann Nguyen, Virginie Zarrouk, Florence Canoui-Poitrine, France Pirenne, Jérôme Mégret, Jean-Michel Pawlotsky, Simon Fillatreau, Pierre Bruhns, Felix A. Rey, Jean-Claude Weill, Claude-Agnès Reynaud, Pascal Chappert, Matthieu Mahévas
Publikováno v:
Immunity
Immunity, Elsevier, 2021, ⟨10.1016/j.immuni.2021.09.011⟩
Immunity, 2021, ⟨10.1016/j.immuni.2021.09.011⟩
Immunity, Elsevier, 2021, ⟨10.1016/j.immuni.2021.09.011⟩
Immunity, 2021, ⟨10.1016/j.immuni.2021.09.011⟩
In addition to serum immunoglobulins, memory B cell (MBC) generation against SARS-CoV-2 represents another layer of immune protection, but the quality of MBC responses in naive and COVID-19-recovered individuals after vaccination remains ill-defined.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e86cbac2285b42434828f87fa219da6
https://hal-pasteur.archives-ouvertes.fr/pasteur-03423964
https://hal-pasteur.archives-ouvertes.fr/pasteur-03423964
Autor:
Pablo Canales-Herrerias, Etienne Crickx, Matteo Broketa, Aurélien Sokal, Guilhem Chenon, Imane Azzaoui, Alexis Vandenberghe, Angga Perima, Bruno Iannascoli, Odile Richard-Le Goff, Carlos Castrillon, Guillaume Mottet, Delphine Sterlin, Ailsa Robbins, Marc Michel, Patrick England, Gael A. Millot, Klaus Eyer, Jean Baudry, Matthieu Mahevas, Pierre Bruhns
The major therapeutic goal for immune thrombocytopenia (ITP) is to restore normal platelet counts using drugs to promote platelet production or by interfering with mechanisms responsible for platelet destruction. 80% of patients possess anti-integrin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd2c8aa5881daae5186e6b06dc873453
https://doi.org/10.1101/2021.06.29.450355
https://doi.org/10.1101/2021.06.29.450355