Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Matteo, Sorge"'
Autor:
Matteo Sorge, Giulia Savoré, Andrea Gallo, Davide Acquarone, Mauro Sbroggiò, Silvia Velasco, Federica Zamporlini, Saveria Femminò, Enrico Moiso, Giampaolo Morciano, Elisa Balmas, Andrea Raimondi, Gabrielle Nattenberg, Rachele Stefania, Carlo Tacchetti, Angela Maria Rizzo, Paola Corsetto, Alessandra Ghigo, Emilia Turco, Fiorella Altruda, Lorenzo Silengo, Paolo Pinton, Nadia Raffaelli, Nathan J Sniadecki, Claudia Penna, Pasquale Pagliaro, Emilio Hirsch, Chiara Riganti, Guido Tarone, Alessandro Bertero, Mara Brancaccio
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 10, Pp 2450-2484 (2024)
Abstract Defining the molecular mechanisms underlying cardiac resilience is crucial to find effective approaches to protect the heart. A physiologic level of ROS is produced in the heart by fatty acid oxidation, but stressful events can boost ROS and
Externí odkaz:
https://doaj.org/article/fbbe12027f6940b5871e50bcfc957a2f
Autor:
Maurizio Vitadello, Matteo Sorge, Elena Percivalle, Elena Germinario, Daniela Danieli‐Betto, Emilia Turco, Guido Tarone, Mara Brancaccio, Luisa Gorza
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 11, Iss 3, Pp 802-819 (2020)
Abstract Background Unloading/disuse induces skeletal muscle atrophy in bedridden patients and aged people, who cannot prevent it by means of exercise. Because interventions against known atrophy initiators, such as oxidative stress and neuronal NO s
Externí odkaz:
https://doaj.org/article/bf8f71caaed14f839a54e7ae851363d0
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
HSP90 is released by cancer cells in the tumor microenvironment where it associates with different co-chaperones generating complexes with specific functions, ranging from folding and activation of extracellular clients to the stimulation of cell sur
Externí odkaz:
https://doaj.org/article/9aa28f7a07fb484291f76ffa92a41f09
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Chronic or acute insults to the myocardium are responsible for the onset of cardiomyopathy and heart failure. Due to the poor regenerative ability of the human adult heart, the survival of cardiomyocytes is a prerequisite to support heart function. C
Externí odkaz:
https://doaj.org/article/6a596d35aaff4099b2d4bf1baad8b28b
Autor:
Claudia Penna, Matteo Sorge, Francesca Tullio, Stefano Comità, Saveria Femminò, Mara Brancaccio, Pasquale Pagliaro
Publikováno v:
Biology, Vol 11, Iss 1, p 146 (2022)
Background: Treatment of myocardial ischemia/reperfusion (IR) injury is still an unmet clinical need. A large variability of remote ischemic conditioning (RIC) protection has been reported; however, no studies have considered the temperature of the i
Externí odkaz:
https://doaj.org/article/b4ed615e77574e3da4c50d246e29a109
Publikováno v:
Cells, Vol 10, Iss 1, p 61 (2021)
The loss of muscle mass and force characterizes muscle atrophy in several different conditions, which share the expression of atrogenes and the activation of their transcriptional regulators. However, attempts to antagonize muscle atrophy development
Externí odkaz:
https://doaj.org/article/01d8fe82a5294c3482bdbdb508949716
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Molecular chaperones are stress proteins that allow the correct folding or unfolding as well as the assembly or disassembly of macromolecular cellular components. Changes in expression and post-translational modifications of chaperones have been link
Externí odkaz:
https://doaj.org/article/871675513bad4f8a8e1efa06c3de86cd
Autor:
Mara Brancaccio, Matteo Sorge
Publikováno v:
Frontiers in Molecular Biosciences, Vol 3 (2016)
Melusin is a chaperone protein selectively expressed in heart and skeletal muscles. Melusin expression levels correlate with cardiac function in pre-clinical models and in human patients with aortic stenosis. Indeed, previous studies in several anima
Externí odkaz:
https://doaj.org/article/dc6c4a2fcaf64551875c363bc99622e3
Autor:
Pietro Arina, Matteo Sorge, Andrea Gallo, Vittoria Di Mauro, Nicoletta Vitale, Paola Cappello, Luca Brazzi, Maria Barandalla-Sobrados, James Cimino, V. Marco Ranieri, Fiorella Altruda, Mervyn Singer, Daniele Catalucci, Mara Brancaccio, Vito Fanelli
Sepsis-induced cardiomyopathy is commonplace and carries an increased risk of death. Melusin, a cardiac muscle-specific chaperone, exerts cardioprotective function under varied stressful conditions through activation of the AKT pathway. The objective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95f6dcbd6df033209f301acdac9f3f39
http://hdl.handle.net/2318/1868082
http://hdl.handle.net/2318/1868082
Autor:
Claudia Penna, Matteo Sorge, Francesca Tullio, Stefano Comità, Saveria Femminò, Mara Brancaccio, Pasquale Pagliaro
Publikováno v:
Biology
Biology, Vol 11, Iss 146, p 146 (2022)
Biology; Volume 11; Issue 1; Pages: 146
Biology, Vol 11, Iss 146, p 146 (2022)
Biology; Volume 11; Issue 1; Pages: 146
Simple Summary Remote ischemic conditioning is a simple cardioprotective practice consisting in brief intermittent ischemia applied to a limb. Remote ischemic conditioning has been repeatedly validated in animal models. However, translation from anim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b47f859cba0d185fe29489e391b2b025
https://pubmed.ncbi.nlm.nih.gov/35053144
https://pubmed.ncbi.nlm.nih.gov/35053144