Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Matteo, Ottolini"'
Autor:
Cassidy T. Burke, Iuliia Vitko, Justyna Straub, Elsa O. Nylund, Agnieszka Gawda, Kathryn Blair, Kyle A. Sullivan, Lara Ergun, Matteo Ottolini, Manoj K. Patel, Edward Perez-Reyes
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 19, p 14467 (2023)
Epileptogenesis is characterized by intrinsic changes in neuronal firing, resulting in hyperactive neurons and the subsequent generation of seizure activity. These alterations are accompanied by changes in gene transcription networks, first with the
Externí odkaz:
https://doaj.org/article/20ab385d109b4165b40fbdef2a460e0f
Autor:
Zdravka Daneva, Matteo Ottolini, Yen Lin Chen, Eliska Klimentova, Maniselvan Kuppusamy, Soham A Shah, Richard D Minshall, Cheikh I Seye, Victor E Laubach, Brant E Isakson, Swapnil K Sonkusare
Publikováno v:
eLife, Vol 10 (2021)
Pannexin 1 (Panx1), an ATP-efflux pathway, has been linked with inflammation in pulmonary capillaries. However, the physiological roles of endothelial Panx1 in the pulmonary vasculature are unknown. Endothelial transient receptor potential vanilloid
Externí odkaz:
https://doaj.org/article/4e52c48d21c241c0a4496dbc4db01f8d
Autor:
John Satkovich, Christopher J. Anderson, Christopher B. Medina, Matteo Ottolini, John R. Lukens, Melissa M. Kendall
Publikováno v:
mBio, Vol 11, Iss 5 (2020)
ABSTRACT Regulated macrophage death has emerged as an important mechanism to defend against intracellular pathogens. However, the importance and consequences of macrophage death during bacterial infection are poorly resolved. This is especially true
Externí odkaz:
https://doaj.org/article/38648c532ec24fd3aca84aa5122be344
Autor:
Bryan S. Barker, Aradhya Nigam, Matteo Ottolini, Ronald P. Gaykema, Nicholas J. Hargus, Manoj K. Patel
Publikováno v:
Neurobiology of Disease, Vol 108, Iss , Pp 183-194 (2017)
Temporal lobe epilepsy (TLE) is a common form of adult epilepsy involving the limbic structures of the temporal lobe. Subiculum neurons act to provide a major output from the hippocampus and consist of a large population of endogenously bursting exci
Externí odkaz:
https://doaj.org/article/14fa8ea87edb456da6a0e2f9b2339e7b
Autor:
Yen-Lin, Chen, Zdravka, Daneva, Maniselvan, Kuppusamy, Matteo, Ottolini, Thomas M, Baker, Eliska, Klimentova, Soham A, Shah, Jennifer D, Sokolowski, Min S, Park, Swapnil K, Sonkusare
Publikováno v:
Circulation. 146(7)
CaWe used SMC-specific TRPV4We provide first evidence that TRPV4Our data identify novel smooth muscle Ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f21253ef02eb1162ca3ad2a7a2e58387
https://pubmed.ncbi.nlm.nih.gov/35758040
https://pubmed.ncbi.nlm.nih.gov/35758040
Autor:
Yen-Lin Chen, Zdravka Daneva, Maniselvan Kuppusamy, Matteo Ottolini, Thomas M. Baker, Eliska Klimentova, Soham A. Shah, Jennifer D. Sokolowski, Min S. Park, Swapnil K. Sonkusare
Publikováno v:
Circulation. 146:548-564
Background: Ca 2+ signals in smooth muscle cells (SMCs) contribute to vascular resistance and control blood pressure. Increased vascular resistance in hypertension has been attributed to impaired SMC Ca 2+ signaling mechanisms. In this regard, transi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26614f4ba73a72ee6f6fbe5441d5ac24
https://doi.org/10.1161/circulationaha.121.058607
https://doi.org/10.1161/circulationaha.121.058607
Publikováno v:
Physiology. 38
Endothelial dysfunction in small arteries is a hallmark of obesity-induced hypertension. Recent studies show that the formation of peroxynitrite, a reactive nitrogen species, impairs endothelium-dependent vasodilation. It is well known that inflammat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf36417c207577f86173f539c907d227
https://doi.org/10.1152/physiol.2023.38.s1.5734848
https://doi.org/10.1152/physiol.2023.38.s1.5734848
Autor:
Yen-Lin Chen, Zdravka Daneva, Maniselvan Kuppusamy, matteo ottolini, Thomas Baker, Eliska Klimentova, Soham Shah, jennifer sokolowski, Min Park, Swapnil K Sonkusare
Publikováno v:
Hypertension. 79
Introduction: Transient receptor potential vanilloid 4 (TRPV4) channel is a crucial Ca 2+ influx pathway in arterial smooth muscle cells (SMCs). However, the effect of SMC TRPV4 (TRPV4 SMC ) channel activity on resting blood pressure has not been inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ccb90e23203fb2ae31bcfa4b0aedc54c
https://doi.org/10.1161/hyp.79.suppl_1.p138
https://doi.org/10.1161/hyp.79.suppl_1.p138
Publikováno v:
Hypertension. 79
Endothelial dysfunction in small arteries is a hallmark of obesity-induced hypertension. Recent studies show that endothelial upregulation of inducible nitric oxide synthase (iNOS) and NADPH oxidase 1 (NOX1) plays a critical role in obesity-induced e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27f6203994563b3674463d22309a1ee5
https://doi.org/10.1161/hyp.79.suppl_1.p134
https://doi.org/10.1161/hyp.79.suppl_1.p134
Autor:
Matteo Ottolini, Swapnil K. Sonkusare
Publikováno v:
Comprehensive Physiology
The contractile state of resistance arteries and arterioles is a crucial determinant of blood pressure and blood flow. Physiological regulation of arterial contractility requires constant communication between endothelial and smooth muscle cells. Var
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c56ffcdfcf01988515769f3660d4890
https://doi.org/10.1002/cphy.c200030
https://doi.org/10.1002/cphy.c200030