Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Mattan, Hurevich"'
Autor:
Jessica Attia, Sivan Nir, Evgeniy Mervinetsky, Dora Balogh, Agata Gitlin-Domagalska, Israel Alshanski, Meital Reches, Mattan Hurevich, Shlomo Yitzchaik
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
Abstract Peptides are commonly used as biosensors for analytes such as metal ions as they have natural binding preferences. In our previous peptide-based impedimetric metal ion biosensors, a monolayer of the peptide was anchored covalently to the ele
Externí odkaz:
https://doaj.org/article/2cb250a498cc43428ff440e2178f5a6a
Publikováno v:
Sensors, Vol 23, Iss 2, p 561 (2023)
The biosensing of bacterial pathogens is of a high priority. Electrochemical biosensors are an important future tool for rapid bacteria detection. A monolayer of bacterial-binding peptides can serve as a recognition layer in such detection devices. H
Externí odkaz:
https://doaj.org/article/9def1149d85d4e23b72e7a36aa600747
Autor:
Daniel Mayer, Fred F. Damberger, Mamidi Samarasimhareddy, Miki Feldmueller, Ziva Vuckovic, Tilman Flock, Brian Bauer, Eshita Mutt, Franziska Zosel, Frédéric H. T. Allain, Jörg Standfuss, Gebhard F. X. Schertler, Xavier Deupi, Martha E. Sommer, Mattan Hurevich, Assaf Friedler, Dmitry B. Veprintsev
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
The cellular functions of arrestins are determined in part by the pattern of phosphorylation on the G protein-coupled receptors (GPCRs) to which arrestins bind. Here, authors use a library of synthetic phosphopeptide analogues of the GPCR rhodopsin C
Externí odkaz:
https://doaj.org/article/3fb017c511b74ac5b642a4f342d8976b
Publikováno v:
Organic & Biomolecular Chemistry. 21:1674-1679
High-Temperature Fast-Stirring Solid-Phase synthesis accelerated the preparation of peptides containing multiple N-glycosylation sites.
Autor:
Alaa Talhami, Avi Swed, Shmuel Hess, Oded Ovadia, Sarit Greenberg, Adi Schumacher-Klinger, David Rosenthal, Deborah E. Shalev, Mattan Hurevich, Philip Lazarovici, Amnon Hoffman, Chaim Gilon
Publikováno v:
Frontiers in Chemistry, Vol 8 (2020)
Painkillers are commonly used medications. Native peptide painkillers suffer from various pharmacological disadvantages, while small molecule painkillers like morphine are highly addictive. We present a general approach aimed to use backbone-cyclizat
Externí odkaz:
https://doaj.org/article/214c0a356de24363ad9340767112adf5
Publikováno v:
Frontiers in Chemistry, Vol 8 (2020)
Cyclic peptide-peptoid hybrids possess improved stability and selectivity over linear peptides and are thus better drug candidates. However, their synthesis is far from trivial and is usually difficult to automate. Here we describe a new rapid and ef
Externí odkaz:
https://doaj.org/article/698baf56e4bb4e8f9196ee702235c8de
Autor:
Kiran Kumar Tadi, Israel Alshanski, Evgeniy Mervinetsky, Gerard Marx, Panayiota Petrou, Karussis M. Dimitrios, Chaim Gilon, Mattan Hurevich, Shlomo Yitzchaik
Publikováno v:
ACS Omega, Vol 2, Iss 12, Pp 8770-8778 (2017)
Externí odkaz:
https://doaj.org/article/d85b8da00c64402c92a5c67bd0935a71
Autor:
Johnny N. Naoum, Koushik Chandra, Dorit Shemesh, R. Benny Gerber, Chaim Gilon, Mattan Hurevich
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 13, Iss 1, Pp 806-816 (2017)
Several multistep strategies were developed to ensure single methylation of amines on solid support. These strategies rely on the introduction of the o-NBS protecting/activating group as a key step. We found that the state-of-the-art strategies fail
Externí odkaz:
https://doaj.org/article/9022c090c61b4f9eb731428ac76ea552
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
Automated glycan assembly has proven a powerful method to rapidly synthesize large oligosaccharides, though stereoselective cis-glycosylation remains a challenge. Here, the authors demonstrate a system to selectively incorporate multiple cis-glycosid
Externí odkaz:
https://doaj.org/article/322fc83fe2004ff7aa51b9b5748470ab
Autor:
Markus W. Weishaupt, Stefan Matthies, Mattan Hurevich, Claney L. Pereira, Heung Sik Hahm, Peter H. Seeberger
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 12, Iss 1, Pp 1440-1446 (2016)
Vaccines against S. pneumoniae, one of the most prevalent bacterial infections causing severe disease, rely on isolated capsular polysaccharide (CPS) that are conjugated to proteins. Such isolates contain a heterogeneous oligosaccharide mixture of di
Externí odkaz:
https://doaj.org/article/f704f9aed74241d8b435dbccf62c5091