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Autor:
Martin C. Chang, Hilmi Ozcelik, Kathy Siminovitch, Aaron L. Goldman, Anna Kiselova, Xuejiang Shi, Mark Dowar, Balram Sukhu, Denise Yee, Nando Di Nicola, Rita A. Kandel, Eric Tram, Matt Vlasschaert
Publikováno v:
The Journal of molecular diagnostics : JMD. 14(5)
Individuals and families carrying mutations in BRCA1 and BRCA2 (BRCA1/2) have a markedly elevated risk of developing breast and ovarian cancers. The first-generation of BRCA1/2 mutation analysis targeted only the coding exons and has implicated prote