Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Matt Theisen"'
Autor:
Stefano Bartesaghi, Kristina Wallenius, Daniel Hovdal, Mathias Liljeblad, Simonetta Wallin, Niek Dekker, Louise Barlind, Nigel Davies, Frank Seeliger, Maria Sörhede Winzell, Sima Patel, Matt Theisen, Luis Brito, Nils Bergenhem, Shalini Andersson, Xiao-Rong Peng
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 28, Iss , Pp 500-513 (2022)
Fibroblast growth factor 21 (FGF21) is a promising therapeutic agent for treatment of type 2 diabetes (T2D) and non-alcoholic steatohepatitis (NASH). We show that therapeutic levels of FGF21 were achieved following subcutaneous (s.c.) administration
Externí odkaz:
https://doaj.org/article/870f12a5c5cf429dbef9b12f15e31262
Autor:
Ding An, Jessica L. Schneller, Andrea Frassetto, Shi Liang, Xuling Zhu, Ji-Sun Park, Matt Theisen, Sue-Jean Hong, Jenny Zhou, Raj Rajendran, Becca Levy, Rebecca Howell, Gilles Besin, Vladimir Presnyak, Staci Sabnis, Kerry E. Murphy-Benenato, E. Sathyajith Kumarasinghe, Timothy Salerno, Cosmin Mihai, Christine M. Lukacs, Randy J. Chandler, Lin T. Guey, Charles P. Venditti, Paolo G.V. Martini
Publikováno v:
Cell Reports, Vol 21, Iss 12, Pp 3548-3558 (2017)
Summary: Isolated methylmalonic acidemia/aciduria (MMA) is a devastating metabolic disorder with poor outcomes despite current medical treatments. Like other mitochondrial enzymopathies, enzyme replacement therapy (ERT) is not available, and although
Externí odkaz:
https://doaj.org/article/48a6dc8892224dcc94c4537810ade1f9
Autor:
Matt Theisen, Jaclyn Milton, Becca Levy, Ling Yin, Andrea Frassetto, Staci Sabnis, Vladimir Presnyak, Gilles Besin, Kerry Benenato, Timothy Salerno, Kristin E. Burke, Andy Lynn, Paolo Martini, Xuling Zhu, Patrick Finn, Christine Lukacs, Lin T. Guey, Summar Siddiqui, Jenny Zhuo, Joe Milano
Publikováno v:
The American Journal of Human Genetics. 104:625-637
Fabry disease is an X-linked lysosomal storage disease caused by loss of alpha galactosidase A (α-Gal A) activity and is characterized by progressive accumulation of globotriaosylceramide and its analogs in all cells and tissues. Although enzyme rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acd9e9f33c8aabfdd3ce162b9e814606
https://doi.org/10.1016/j.ajhg.2019.02.003
https://doi.org/10.1016/j.ajhg.2019.02.003
Autor:
Gilles Besin, Vladimir Presnyak, Kerry E. Murphy-Benenato, Lin T. Guey, Timothy Salerno, Andrea Frassetto, Shi Liang, Jenny Zhou, Jessica L. Schneller, Cosmin Mihai, Christine Lukacs, Sue Jean Hong, Becca Levy, Raj Rajendran, Paolo Martini, Xuling Zhu, Ji Sun Park, E. Sathyajith Kumarasinghe, Staci Sabnis, Rebecca Howell, Randy J. Chandler, Charles P. Venditti, Ding An, Matt Theisen
Publikováno v:
Cell Reports, Vol 21, Iss 12, Pp 3548-3558 (2017)
Summary: Isolated methylmalonic acidemia/aciduria (MMA) is a devastating metabolic disorder with poor outcomes despite current medical treatments. Like other mitochondrial enzymopathies, enzyme replacement therapy (ERT) is not available, and although
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d51c4de3877540689b446b0a9a435d8
https://doi.org/10.1016/j.celrep.2018.08.049
https://doi.org/10.1016/j.celrep.2018.08.049
Autor:
Andy Lynn, Ling Yin, Gilles Besin, Xuling Zhu, Lin T. Guey, Kerry Benenato, Andrea Frassetto, Jenny Zhuo, Nancy M. Dahms, James J. Miller, Becca Levy, Summar Siddiqui, Christine Lukacs, Carly A Murphy, Joe Milano, Angela K. Beltrame, Paolo Martini, Vladimir Presnyak, Matt Theisen, Rebecca Howell
Publikováno v:
Molecular Genetics and Metabolism. 123:S153
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee5fb2fca44c1000b49c746427635596
https://doi.org/10.1016/j.ymgme.2017.12.425
https://doi.org/10.1016/j.ymgme.2017.12.425