Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Matt Soars"'
Autor:
Matt Soars, Lisa M. Kopcho, Carolyn A. Weigelt, Shilpa Demes, Gregory D. Vite, Mary J. Harner, Rohit Malik, Guo Li, David G. Harden, Charles F. Voliva, Kevin O’Malley, Zheming Ruan, Lan-Ying Qin, Brian J. Arey, Peter K. Park, Jennifer Price, Steven Sheriff, Gerald J. Duke, Ashvinikumar V. Gavai, JIngjing Deng, Brian E. Fink, Christopher M. Barbieri, Max Ruzanov, Muge Celiktas, Mark R. Witmer, Yuval Blat, William D. Schmitz, Joseph G. Naglich, Iyoncy Rodrigo
Publikováno v:
Cancer Research. 81:1140-1140
The chromosome 9p21 (chr9p21) locus is deleted in almost 10% of all cancer types. This locus includes the CDKN2A gene that encodes the critical tumor suppressors p19-ARF and p16-INK4a. Methylthioadenosine phosphorylase (MTAP), a gene proximal to CDKN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::769a298e5dedd6469a5cf85008a3a619
https://doi.org/10.1158/1538-7445.am2021-1140
https://doi.org/10.1158/1538-7445.am2021-1140
Autor:
Michael Gill, Matt Soars, Robert F. Kaltenbach, Mosure Kathy, Peter T. W. Cheng, Anthony V. Azzara, Stephen S. Kalinowski, Shiwei Tao, Chen-Pin Hung, Larry Kennedy, Yan Shi, Lisa Burns, Julia Sapuppo, Tao Wang, David A. Gordon, Roble Jeffrey, Cvijic Mary-Ellen, Hao Zhang, Ching-Hsuen Chu, Reddigunta Ramesh Babu, Jun Shi, Bruce A. Ellsworth, Jun Li, Bradley A. Zinker, Brian J. Murphy, Dhanusu Suresh, Joseph R. Taylor, Ying Wang, Chi-Shing Sum, Ziegler Milinda, Rebekah Heiry, Steve Walker, Stephanie Boehm
Publikováno v:
Idiopathic interstitial pneumonias.
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive and fatal fibrosing lung disease with limited approved treatment options. The bioactive lysophospholipid lysophosphatidic acid (LPA) and the LPA1 receptor have been implicated in the etiol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b54aea41cff0b233b97a0c88ca4d9ae
https://doi.org/10.1183/13993003.congress-2019.pa5383
https://doi.org/10.1183/13993003.congress-2019.pa5383
Autor:
Aaron Rigby, Peter J. H. Webborn, Rob Riley, John Collington, Mark Furber, Brian Springthorpe, Matt Soars, Ash Bahl, Cathy MacDonald, Keith Bowers, Elizabeth Kinchin, Lilian Alcaraz, Rebecca Denton, Haydn Beaton, David Donald, Christopher A. Luckhurst
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 22:7707-7710
The second part of this communication focuses on the resolution of issues surrounding the series of hydroxyamide phenoxypiperidine CCR3/H(1) dual antagonists described in Part I. This involved further structural exploration directed at reducing metab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a2660289e12b8effe0ecbfde4d5f050
https://doi.org/10.1016/j.bmcl.2012.09.112
https://doi.org/10.1016/j.bmcl.2012.09.112
Publikováno v:
Toxicology Letters. :333-340
Human gene families encoding UDP-Glucuronosyltransferases (UGTs) have been identified and partially characterised. This family of enzymes catalysed the glucuronidation of drugs, xenobiotics and endobiotics. Genetic mutations and polymorphisms have be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e422c8028f09d01490be10c7cdd8fc60
https://doi.org/10.1016/s0378-4274(99)00209-x
https://doi.org/10.1016/s0378-4274(99)00209-x
Autor:
Mark, Furber, Lilian, Alcaraz, Christopher, Luckhurst, Ash, Bahl, Haydn, Beaton, Keith, Bowers, John, Collington, Rebecca, Denton, David, Donald, Elizabeth, Kinchin, Cathy, MacDonald, Aaron, Rigby, Rob, Riley, Matt, Soars, Brian, Springthorpe, Peter, Webborn
Publikováno v:
Bioorganicmedicinal chemistry letters. 22(24)
The second part of this communication focuses on the resolution of issues surrounding the series of hydroxyamide phenoxypiperidine CCR3/H(1) dual antagonists described in Part I. This involved further structural exploration directed at reducing metab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b265960f1cf196e20fed3d284455964f
https://pubmed.ncbi.nlm.nih.gov/23116889
https://pubmed.ncbi.nlm.nih.gov/23116889
Publikováno v:
Xenobiotica. Jan2023, Vol. 53 Issue 1, p66-68. 3p.
Publikováno v:
Journal of the International AIDS Society. Oct2016 Supplement S7, Vol. 19, pn/a-n/a. 277p. 2 Color Photographs, 10 Diagrams, 130 Charts, 77 Graphs.
Publikováno v:
Journal of the International AIDS Society. 2016 Supplement, Vol. 19, p23-259. 237p. 1 Color Photograph, 2 Diagrams, 126 Charts, 76 Graphs.
Autor:
Sharma, P.1 (AUTHOR) Pradeep.Sharma@astrazeneca.com, Holmes, V. E.1 (AUTHOR), Elsby, R.1 (AUTHOR), Lambert, C.1 (AUTHOR), Surry, D.1 (AUTHOR)
Publikováno v:
Xenobiotica. Jan2010, Vol. 40 Issue 1, p24-37. 14p. 2 Diagrams, 3 Charts, 5 Graphs.
Publikováno v:
Drug Metabolism Reviews. Dec2000 Supplement, Vol. 32, pvii-120. 114p.