Predicting deep infection in pilon and tibial plateau fractures: a secondary analysis of the VANCO and OXYGEN trials

Autor: Archie L. Overmann, MD, Anthony R. Carlini, MS, Robert V. O'Toole, MD, Renan C. Castillo, PhD, Nathan N. O'Hara, PhD, MHA, METRC, Eben A. Carroll, MD, James Brett Goodman, MBA, Martha B. Holden, AAS, AA, Anna N. Miller, MD, Amanda Spraggs-Hughes, PhD, Michael L. Brennan, MD, Paul Tornetta, III, MD, Patrick M. Osborn, MD, Jessica C. Rivera, MD, PhD, Clinton K. Murray, MD, Joseph E. Kimmel, MS, Michael J. Bosse, MD, Joseph R. Hsu, MD, Madhav A. Karunakar, MD, Laurence B. Kempton, MD, Rachel B. Seymour, PhD, Stephen H. Sims, MD, Christine Churchill, MA, Debra L. Sietsema, PhD, RN, Ida Leah Gitajn, MD, MS, Rachel M. Reilly, MD, Robert D. Zura, MD, Cameron Howes, BA, Hassan Mir, MD, MBA, Michael J. Weaver, MD, Marilyn Heng, MD, MPH, Thuan V. Ly, MD, Emily A. Wagstrom, MD, Jerald R. Westberg, MPH, BA, Brian H. Mullis, MD, Jeffrey O. Anglen, MD, Leilani S. Mullis, MD, Karl D. Shively, MD, Todd O. McKinley, MD, Roman M. Natoli, MD, PhD, Anthony Sorkin, MD, Lauren C. Hill, BS, CCRC, Robert A. Hymes, MD, Greg E. Gaski, MD, A. Stephen Malekzadeh, MD, Lolita Ramsey, PhD, RN, Jeff E. Schulman, MD, Cary C. Schwartzbach, MD, Robert A. Sikorski, MD, Olivia C. Lee, MD, Peter C. Krause, MD, Joshua L. Gary, MD, Timothy S. Achor, MD, Andrew Choo, MD, John W. Munz, MD, Sterling J. Boutte, BS, Matthew C. Galpin, CCRC, H. Michael Frisch, MD, Adam M. Kaufman, MD, C. Michael LeCroy, MD, Christopher S. Smith, MD, Alec C. Stall, MD, MPH, Andrea Horne, MA, CCRP, Manjari Joshi, MBBS, Jason W. Nascone, MD, Marcus F. Sciadini, MD, Gerard P. Slobogean, MD, Andrea L. Howe, BS, Roman Hayda, MD, Andrew R. Evans, MD, Stanislaw P. Stawicki, MD, MBA, Thomas R. Wojda, MD, MBA, Michael J. Gardner, MD, Julius A. Bishop, MD, Saqib Rehman, MD, MBA, Cyrus Caroom, MD, Elizabeth Sheridan, MPH, MACPR, Theodore Miclau, MD, Saam Morshed, MD, PhD, Thomas F. Higgins, MD, Justin M. Haller, MD, Clay A. Spitler, MD, Massimo Max Morandi, MD, FACS, Paul Edward Matuszewski, MD, Arun Aneja, MD, PhD, Patrick F. Bergin, MD, Eldrin Bhanat, MD, MPH, Matt L. Graves, MD, John Morellato, MBBS Hons, David Teague, MD, William Ertl, MD, Jaimo Ahn, MD, PhD, Gele B. Moloney, MD, John C. Weinlein, MD, Boris A. Zelle, MD, Animesh Agarwal, MD, Ravi A. Karia, MD, Ashoke Sathy, MD, Drew Sanders, MD, MPH, David B. Weiss, MD, Seth R. Yarboro, MD, Veronica Lester-Ballard, MSN, Eric D. McVey, MEd, CCRP, Reza Firoozabadi, MD, MA, Arman Dagal, MD, FRCA, Conor P. Kleweno, MD, Julie Agel, MA, Paul S. Whiting, MD, Natasha M. Simske, BS, Alexander B. Siy, BS, William T. Obremskey, MD, MPH, Basem Attum, MD, Eduardo J. Burgos, MD, Vamshi Gajari, MBBS, A. Alex Jahangir, MD, Andres Rodriguez-Buitrago, MD, Manish Sethi, MD, Daniel J. Stinner, MD, PhD, Rajesh R. Tummuru, MBBS, MBA, Karen M. Trochez, MA, BS, Jean-Claude G. D'Alleyrand, MD, MSE, Lauren E. Allen, DrPH, Susan C. Collins, MSc, Yanjie Huang, ScM, Tara J. Taylor, MPH

Publikováno v: OTA International, Vol 7, Iss 4 (2024)

Abstract. Objectives:. To develop and validate a prediction model for a deep surgical site infection (SSI) after fixation of a tibial plateau or pilon fracture. Design:. Pooled data from 2 randomized trials (VANCO and OXYGEN). Setting:. Fifty-two US

Externí odkaz: https://doaj.org/article/f526c1bca38a46778b5055dcf59b14aa

Improving Circulation Half-Life of Therapeutic Candidate N-TIMP2 by Unfolded Peptide Extension

Autor: Jason Shirian, Alexandra Hockla, Justyna J. Gleba, Matt Coban, Naama Rotenberg, Laura M. Strik, Aylin Alasonyalilar Demirer, Matt L. Pawlush, John A. Copland, Evette S. Radisky, Julia M. Shifman

Publikováno v: Biomolecules, Vol 14, Iss 9, p 1187 (2024)

Matrix metalloproteinases (MMPs) are significant drivers of many diseases, including cancer, and are established targets for drug development. Tissue inhibitors of metalloproteinases (TIMPs) are endogenous MMP inhibitors and are being pursued for the

Externí odkaz: https://doaj.org/article/b253b19360e542278f32a16290c84c97

Alkylamine‐Functionalized Carbon Supports to Enhance the Silver Nanoparticles Electrocatalytic Reduction of CO2 to CO

Autor: Francesco Mattarozzi, Karen van denAkker, Matt L. J. Peerlings, Maaike E. T. Vink‐van Ittersum, Nienke L. Visser, Rim C. J. van dePoll, Prof. Dr. Emiel J. M. Hensen, Dr. Peter Ngene, Prof. Dr. Petra E. deJongh

Publikováno v: ChemElectroChem, Vol 10, Iss 19, Pp n/a-n/a (2023)

Abstract Silver electrocatalysts enable the conversion of CO2 to CO, thereby facilitating the transition to a carbon neutral society. To lower the cost of the expensive metal, silver nanostructures are often supported on carbon. This substrate offers

Externí odkaz: https://doaj.org/article/f991b822ec734e73ae3cc4d87f027a15

Exploring the potential of using simulation games for engaging with sheep farmers about lameness recognition

Autor: Matt L. Jones, Maxwell S. Barnish, Robert R. Hughes, Aimee K. Murray, Omid Mansour, Tiziana Loni, Holly M. Vickery, Myfanwy L. Evans, Laura Green, Nervo Verdezoto

Publikováno v: Frontiers in Veterinary Science, Vol 10 (2023)

IntroductionComputer simulation games are increasingly being used in agriculture as a promising tool to study, support and influence real-life farming practices. We explored the potential of using simulation games to engage with sheep farmers on the

Externí odkaz: https://doaj.org/article/50985346fbcf4b2d9f40aad48a20502f

Disentangling transients and their host galaxies with Scarlet2: A framework to forward model multi-epoch imaging

Autor: Ward, Charlotte, Melchior, Peter, Sampson, Matt L., Burke, Colin J., Siegel, Jared, Remy, Benjamin, Birmingham, Sufia, Ramey, Emily, van Velzen, Sjoert

Many science cases for wide-field time-domain surveys rely on accurate identification and characterization of the galaxies hosting transient and variable objects. In the era of the Legacy Survey of Space and Time (LSST) at the Vera C. Rubin Observato

Externí odkaz: http://arxiv.org/abs/2409.15427