Výsledky vyhledávání - "Matt J. Zaya"

Dopamine D3 Receptor Antagonists. 1. Synthesis and Structure−Activity Relationships of 5,6-Dimethoxy-N-alkyl- and N-Alkylaryl-Substituted 2-Aminoindans

Autor: Martin W. Smith, Kjell Svensson, Matt J. Zaya, Susanne R. Haadsma-Svensson, Mary E. Lajiness, Nanette F. Nichols, Chiu-Hong Lin, Rita M. Huff, Christopher L. Haber, Kerry Anne Cleek, J. Neil Duncan, Dac M. Dinh, and Arvid Carlsson

Publikováno v: Journal of Medicinal Chemistry. 44:4716-4732

5,6-Dimethoxy-2-(N-dipropyl)-aminoindan (3, PNU-99194A) was found to be a selective dopamine D(3) receptor antagonist with potential antipsychotic properties in animal models. To investigate the effects of nitrogen substitution on structure-activity

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50895a57b406c01e185736e122556b86
https://doi.org/10.1021/jm010145w

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