Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Matt Coban"'
Autor:
Jason Shirian, Alexandra Hockla, Justyna J. Gleba, Matt Coban, Naama Rotenberg, Laura M. Strik, Aylin Alasonyalilar Demirer, Matt L. Pawlush, John A. Copland, Evette S. Radisky, Julia M. Shifman
Publikováno v:
Biomolecules, Vol 14, Iss 9, p 1187 (2024)
Matrix metalloproteinases (MMPs) are significant drivers of many diseases, including cancer, and are established targets for drug development. Tissue inhibitors of metalloproteinases (TIMPs) are endogenous MMP inhibitors and are being pursued for the
Externí odkaz:
https://doaj.org/article/b253b19360e542278f32a16290c84c97
Autor:
Hezi Hayun, Matt Coban, Ashok Kumar Bhagat, Eden Ozer, Lital Alfonta, Thomas R. Caulfield, Evette S. Radisky, Niv Papo
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Matrix metalloproteinases (MMPs) regulate the degradation of extracellular matrix (ECM) components in biological processes. MMP activity is controlled by natural tissue inhibitors of metalloproteinases (TIMPs) that non-selectively inhibit th
Externí odkaz:
https://doaj.org/article/9302df7774f5463d897a9547d6d88c2a
Autor:
Naeyma N. Islam, Caleb A. Weber, Matt Coban, Liam T. Cocker, Fabienne C. Fiesel, Wolfdieter Springer, Thomas R. Caulfield
Publikováno v:
Biomolecules, Vol 14, Iss 3, p 365 (2024)
Complete loss-of-function mutations in the PRKN gene are a major cause of early-onset Parkinson’s disease (PD). PRKN encodes the Parkin protein, an E3 ubiquitin ligase that works in conjunction with the ubiquitin kinase PINK1 in a distinct quality
Externí odkaz:
https://doaj.org/article/99e78e36cc994780a3be252ae9a5c6cc
Publikováno v:
Biomolecules, Vol 9, Iss 11, p 745 (2019)
In-frame decoding in the ribosome occurs through canonical or wobble Watson−Crick pairing of three mRNA codon bases (a triplet) with a triplet of anticodon bases in tRNA. Departures from the triplet−triplet interaction can result in frameshifting
Externí odkaz:
https://doaj.org/article/9d58bc9e232d4a74b8a743cbf7419cd9
Publikováno v:
ASPET 2023 Annual Meeting Abstract - Cellular and Molecular Pharmacology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3eb9171b6440855aac535b766a51f84
https://doi.org/10.1124/jpet.122.182650
https://doi.org/10.1124/jpet.122.182650
Autor:
Yash Gupta, Oleksandr V. Savytskyi, Matt Coban, Amoghavarsha Venugopal, Vasili Pleqi, Caleb A. Weber, Rohit Chitale, Ravi Durvasula, Christopher Hopkins, Prakasha Kempaiah, Thomas R. Caulfield
Publikováno v:
Molecular aspects of medicine.
With more than 5 million fatalities and close to 300 million reported cases, COVID-19 is the first documented pandemic due to a coronavirus that continues to be a major health challenge. Despite being rapid, uncontrollable, and highly infectious in i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48bc09f9724f575312279fb7fa11e6d4
https://pubmed.ncbi.nlm.nih.gov/36371228
https://pubmed.ncbi.nlm.nih.gov/36371228
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61d66273c857199ac0c694e658f8a6d2
https://doi.org/10.1096/fasebj.2022.36.s1.r3528
https://doi.org/10.1096/fasebj.2022.36.s1.r3528
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0b2c3194a7e2c3c6098c6394e514f57
https://doi.org/10.1096/fasebj.2022.36.s1.r4426
https://doi.org/10.1096/fasebj.2022.36.s1.r4426
Publikováno v:
Journal of Biological Chemistry. 299:103286
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6535e8b21733fe080b8dad58f74d81d9
https://doi.org/10.1016/j.jbc.2023.103286
https://doi.org/10.1016/j.jbc.2023.103286
Autor:
Anat Shahar, Itay Cohen, Alexandra Hockla, Shiran Lacham, Niv Papo, Matt Coban, Banumathi Sankaran, Thomas R. Caulfield, Evette S. Radisky
Publikováno v:
The Journal of biological chemistry, vol 294, iss 13
Serine protease inhibitors of the Kunitz-bovine pancreatic trypsin inhibitor (BPTI) family are ubiquitous biological regulators of proteolysis. These small proteins are resistant to proteolysis, but can be slowly cleaved within the protease-binding l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fced9ad9780cf07e038d50866ad08bf5
https://doi.org/10.1074/jbc.ra118.007292
https://doi.org/10.1074/jbc.ra118.007292