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Hyperpolarized ¹³ C Magnetic Resonance Imaging of Fumarate Metabolism by Parahydrogen-induced Polarization: A Proof-of-Concept in vivo Study.

Autor: Stewart NJ; Division of Bioengineering & Bioinformatics, Graduate School of Information Science & Technology, Hokkaido University, North 14, West 9, Kita-ku, Sapporo, Hokkaido, 060-0814, Japan., Nakano H; Division of Bioengineering & Bioinformatics, Graduate School of Information Science & Technology, Hokkaido University, North 14, West 9, Kita-ku, Sapporo, Hokkaido, 060-0814, Japan., Sugai S; Division of Bioengineering & Bioinformatics, Graduate School of Information Science & Technology, Hokkaido University, North 14, West 9, Kita-ku, Sapporo, Hokkaido, 060-0814, Japan., Tomohiro M; Division of Bioengineering & Bioinformatics, Graduate School of Information Science & Technology, Hokkaido University, North 14, West 9, Kita-ku, Sapporo, Hokkaido, 060-0814, Japan., Kase Y; Division of Bioengineering & Bioinformatics, Graduate School of Information Science & Technology, Hokkaido University, North 14, West 9, Kita-ku, Sapporo, Hokkaido, 060-0814, Japan., Uchio Y; Division of Bioengineering & Bioinformatics, Graduate School of Information Science & Technology, Hokkaido University, North 14, West 9, Kita-ku, Sapporo, Hokkaido, 060-0814, Japan., Yamaguchi T; Division of Computational Chemistry, Transition State Technology Co. Ltd. 2-16-1 Tokiwadai, Ube, Yamaguchi, 755-8611, Japan., Matsuo Y; Division of Computational Chemistry, Transition State Technology Co. Ltd. 2-16-1 Tokiwadai, Ube, Yamaguchi, 755-8611, Japan., Naganuma T; R&D Department, Japan REDOX Ltd. 4-29-49-805 Chiyo, Hakata-ku, Fukuoka, 812-0044, Japan., Takeda N; Division of Cardiology and Metabolism, Center for Molecular Medicine, Jichi, Medical University, 3311-1, Yakushiji, Shimotsuke-shi, Tochigi 329-0498, Japan., Nishimura I; Division of Bioengineering & Bioinformatics, Graduate School of Information Science & Technology, Hokkaido University, North 14, West 9, Kita-ku, Sapporo, Hokkaido, 060-0814, Japan., Hirata H; Division of Bioengineering & Bioinformatics, Graduate School of Information Science & Technology, Hokkaido University, North 14, West 9, Kita-ku, Sapporo, Hokkaido, 060-0814, Japan., Hashimoto T; Chiba Iodine Resource Innovation Center and Department of Chemistry, Graduate School of Science, Chiba University, 1-33 Yayoi-cho, Inage-ku, Chiba, 263-8522, Japan., Matsumoto S; Division of Bioengineering & Bioinformatics, Graduate School of Information Science & Technology, Hokkaido University, North 14, West 9, Kita-ku, Sapporo, Hokkaido, 060-0814, Japan.

Publikováno v: Chemphyschem : a European journal of chemical physics and physical chemistry [Chemphyschem] 2021 May 17; Vol. 22 (10), pp. 905.