The Roles of Mitochondria in Human Being's Life and Aging.

Autor: Indo HP; Department of Oncology, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima City 890-8544, Japan.; Amanogawa Galactic Astronomy Research Center (AGARC), Kagoshima University Graduate School of Sciences and Engineering, 1-21-40 Korimoto, Kagoshima 890-0065, Japan., Chatatikun M; School of Allied Health Sciences, Walailak University, Thasala 80161, Thailand.; Research Excellence Center for Innovation and Health Products (RECIHP), School of Allied Health Sciences, Walailak University, Thasala Nakhon Si Thammarat 80160, Thailand., Nakanishi I; Quantum RedOx Chemistry Team, Quantum Life Spin Group, Institute for Quantum Life Science (iQLS), National Institutes for Quantum Science and Technology (QST), 4-9-1 Anagawa, Inage-ku, Chiba 263-8555, Japan., Matsumoto KI; Quantitative RedOx Sensing Group, Department of Radiation Regulatory Science Research, Institute for Radiological Science (NIRS), National Institutes for Quantum Science and Technology (QST), 4-9-1 Anagawa, Inage-ku, Chiba 263-8555, Japan., Imai M; Department of Molecular Diagnostics, School of Allied Health Sciences, Kitasato University, 1-15-1 Kitasato, Sagamihara 252-0373, Japan.; Department of Applied Tumor Pathology, Graduate School of Medical Sciences, Kitasato University, Sagamihara 252-0374, Japan.; Regenerative Medicine and Cell Design Research Facility, School of Allied Health Sciences, Kitasato University, 1-15-1 Kitasato, Sagamihara 252-0373, Japan., Kawakami F; Regenerative Medicine and Cell Design Research Facility, School of Allied Health Sciences, Kitasato University, 1-15-1 Kitasato, Sagamihara 252-0373, Japan.; Department of Regulation Biochemistry, Graduate School of Medical Sciences, Kitasato University, 1-15-1 Kitasato, Sagamihara 252-0373, Japan.; Department of Health Administration, School of Allied Health Sciences, Kitasato University, 1-15-1 Kitasato, Sagamihara 252-0373, Japan., Kubo M; Regenerative Medicine and Cell Design Research Facility, School of Allied Health Sciences, Kitasato University, 1-15-1 Kitasato, Sagamihara 252-0373, Japan.; Department of Environmental Microbiology, Graduate School of Medical Sciences, Kitasato University, 1-15-1 Kitasato, Sagamihara 252-0373, Japan., Abe H; Department of Oncology, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima City 890-8544, Japan., Ichikawa H; Department of Medical Life Systems, Graduate School of Life and Medical Sciences, Doshishia University, Kyoto 610-0394, Japan., Yonei Y; Anti-Aging Medical Research Center and Glycation Stress Research Center, Graduate School of Life and Medical Sciences, Doshisha University, Kyoto 610-0394, Japan., Beppu HJ; Dr. Beppu's Oral Health Care & Anti-Aging Clinic, Chuo-ku, Tokyo 103-0027, Japan., Minamiyama Y; Food Hygiene and Environmental Health Division of Applied Life Science, Graduate School of Life and Environmental Sciences, Kyoto Prefectural University, Sakyo-ku, Kyoto 606-8522, Japan., Kanekura T; Department of Dermatology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima 890-8544, Japan., Ichikawa T; Regenerative Medicine and Cell Design Research Facility, School of Allied Health Sciences, Kitasato University, 1-15-1 Kitasato, Sagamihara 252-0373, Japan.; Department of Regulation Biochemistry, Graduate School of Medical Sciences, Kitasato University, 1-15-1 Kitasato, Sagamihara 252-0373, Japan., Phongphithakchai A; Division of Nephrology, Department of Internal Medicine, Faculty of Medicine, Prince of Songkla University, Songkhla 90110, Thailand., Udomwech L; School of Medicine, Walailak University, Thasala 80161, Thailand., Sukati S; School of Allied Health Sciences, Walailak University, Thasala 80161, Thailand.; Hematology and Transfusion Science Research Center (HTSRC), School of Allied Health Sciences, Walailak University, Nakhon Si Thammarat 80160, Thailand., Charong N; School of Allied Health Sciences, Walailak University, Thasala 80161, Thailand.; Hematology and Transfusion Science Research Center (HTSRC), School of Allied Health Sciences, Walailak University, Nakhon Si Thammarat 80160, Thailand., Somsak V; School of Allied Health Sciences, Walailak University, Thasala 80161, Thailand.; Research Excellence Center for Innovation and Health Products (RECIHP), School of Allied Health Sciences, Walailak University, Thasala Nakhon Si Thammarat 80160, Thailand., Tangpong J; School of Allied Health Sciences, Walailak University, Thasala 80161, Thailand.; Research Excellence Center for Innovation and Health Products (RECIHP), School of Allied Health Sciences, Walailak University, Thasala Nakhon Si Thammarat 80160, Thailand., Nomura S; Department of Clinical Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, Hoshi University, 2-4-41 Ebara, Shinagawa-ku, Tokyo 142-8501, Japan.; Isotope Science Center, The University of Tokyo, 2-22-16 Yayoi, Bunkyo-ku, Tokyo 113-0032, Japan.; Department of Gastrointestinal Surgery, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan., Majima HJ; School of Allied Health Sciences, Walailak University, Thasala 80161, Thailand.; Research Excellence Center for Innovation and Health Products (RECIHP), School of Allied Health Sciences, Walailak University, Thasala Nakhon Si Thammarat 80160, Thailand.

Publikováno v: Biomolecules [Biomolecules] 2024 Oct 17; Vol. 14 (10). Date of Electronic Publication: 2024 Oct 17.

Treatment of spontaneously hypertensive rats during pregnancy and lactation with the antioxidant tempol lowers blood pressure and reduces oxidative stress.

Autor: Kawakami K; Department of Experimental Animals, Interdisciplinary Center for Science Research, Head Office for Research and Academic Information, Shimane University, 89-1 Enya-cho, Izumo, Shimane 693-8501, Japan., Matsuo H; Department of Experimental Animals, Interdisciplinary Center for Science Research, Head Office for Research and Academic Information, Shimane University, 89-1 Enya-cho, Izumo, Shimane 693-8501, Japan., Kajitani N; Department of Experimental Animals, Interdisciplinary Center for Science Research, Head Office for Research and Academic Information, Shimane University, 89-1 Enya-cho, Izumo, Shimane 693-8501, Japan., Matsumoto KI; Department of Biosignaling and Radioisotope Experiment, Interdisciplinary Center for Science Research, Head Office for Research and Academic Information, Shimane University, 89-1 Enya-cho, Izumo, Shimane 693-8501, Japan.

Publikováno v: Experimental animals [Exp Anim] 2024 May 03; Vol. 73 (2), pp. 136-144. Date of Electronic Publication: 2023 Oct 12.

Large-scale animal model study uncovers altered brain pH and lactate levels as a transdiagnostic endophenotype of neuropsychiatric disorders involving cognitive impairment.

Autor: Hagihara H; Division of Systems Medical Science, Center for Medical Science, Fujita Health University, Toyoake, Japan., Shoji H; Division of Systems Medical Science, Center for Medical Science, Fujita Health University, Toyoake, Japan., Hattori S; Division of Systems Medical Science, Center for Medical Science, Fujita Health University, Toyoake, Japan., Sala G; Division of Systems Medical Science, Center for Medical Science, Fujita Health University, Toyoake, Japan., Takamiya Y; Division of Systems Medical Science, Center for Medical Science, Fujita Health University, Toyoake, Japan., Tanaka M; Division of Systems Medical Science, Center for Medical Science, Fujita Health University, Toyoake, Japan., Ihara M; Department of Neurology, National Cerebral and Cardiovascular Center, Suita, Japan., Shibutani M; Laboratory of Genome Science, Biosignal Genome Resource Center, Institute for Molecular and Cellular Regulation, Gunma University, Maebashi, Japan., Hatada I; Laboratory of Genome Science, Biosignal Genome Resource Center, Institute for Molecular and Cellular Regulation, Gunma University, Maebashi, Japan., Hori K; Department of Biochemistry and Cellular Biology, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Kodaira, Japan., Hoshino M; Department of Biochemistry and Cellular Biology, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Kodaira, Japan., Nakao A; Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Kyoto, Japan., Mori Y; Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Kyoto, Japan., Okabe S; Department of Cellular Neurobiology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan., Matsushita M; Department of Molecular Cellular Physiology, Graduate School of Medicine, University of the Ryukyus, Nishihara, Japan., Urbach A; Department of Neurology, Jena University Hospital, Jena, Germany., Katayama Y; Department of Molecular and Cellular Biology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan., Matsumoto A; Department of Molecular and Cellular Biology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan., Nakayama KI; Department of Molecular and Cellular Biology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan., Katori S; Laboratory of Mammalian Neural Circuits, National Institute of Genetics, Mishima, Japan., Sato T; Laboratory of Mammalian Neural Circuits, National Institute of Genetics, Mishima, Japan., Iwasato T; Laboratory of Mammalian Neural Circuits, National Institute of Genetics, Mishima, Japan., Nakamura H; Department of Molecular Pharmacology and Neurobiology, Yokohama City University Graduate School of Medicine, Yokohama, Japan., Goshima Y; Department of Molecular Pharmacology and Neurobiology, Yokohama City University Graduate School of Medicine, Yokohama, Japan., Raveau M; Laboratory for Neurogenetics, RIKEN Center for Brain Science, Wako, Japan., Tatsukawa T; Laboratory for Neurogenetics, RIKEN Center for Brain Science, Wako, Japan., Yamakawa K; Laboratory for Neurogenetics, RIKEN Center for Brain Science, Wako, Japan.; Department of Neurodevelopmental Disorder Genetics, Institute of Brain Sciences, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan., Takahashi N; Laboratory of Structural Physiology, Center for Disease Biology and Integrative Medicine, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.; Department of Physiology, Kitasato University School of Medicine, Sagamihara, Japan., Kasai H; Laboratory of Structural Physiology, Center for Disease Biology and Integrative Medicine, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.; International Research Center for Neurointelligence (WPI-IRCN), UTIAS, The University of Tokyo, Tokyo, Japan., Inazawa J; Research Core, Tokyo Medical and Dental University, Tokyo, Japan., Nobuhisa I; Department of Stem Cell Regulation, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan., Kagawa T; Department of Stem Cell Regulation, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan., Taga T; Department of Stem Cell Regulation, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan., Darwish M; Department of Biochemistry, Faculty of Pharmacy, Cairo University, Cairo, Egypt.; Department of Behavioral Physiology, Graduate School of Innovative Life Science, University of Toyama, Toyama, Japan., Nishizono H; Medical Research Institute, Kanazawa Medical University, Kahoku, Japan., Takao K; Department of Behavioral Physiology, Graduate School of Innovative Life Science, University of Toyama, Toyama, Japan.; Department of Behavioral Physiology, Faculty of Medicine, University of Toyama, Toyama, Japan., Sapkota K; Department of Neuroscience, Southern Research, Birmingham, United States., Nakazawa K; Department of Neuroscience, Southern Research, Birmingham, United States., Takagi T; Institute for Developmental Research, Aichi Developmental Disability Center, Kasugai, Japan., Fujisawa H; Department of Endocrinology, Diabetes and Metabolism, School of Medicine, Fujita Health University, Toyoake, Japan., Sugimura Y; Department of Endocrinology, Diabetes and Metabolism, School of Medicine, Fujita Health University, Toyoake, Japan., Yamanishi K; Department of Neuropsychiatry, Hyogo Medical University School of Medicine, Nishinomiya, Japan., Rajagopal L; Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago, United States., Hannah ND; Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago, United States., Meltzer HY; Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago, United States., Yamamoto T; Department of Molecular Neurobiology, Faculty of Medicine, Kagawa University, Kita-gun, Japan., Wakatsuki S; Department of Peripheral Nervous System Research, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Tokyo, Japan., Araki T; Department of Peripheral Nervous System Research, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Tokyo, Japan., Tabuchi K; Department of Molecular & Cellular Physiology, Shinshu University School of Medicine, Matsumoto, Japan., Numakawa T; Department of Mental Disorder Research, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Kodaira, Japan., Kunugi H; Department of Mental Disorder Research, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Kodaira, Japan.; Department of Psychiatry, Teikyo University School of Medicine, Tokyo, Japan., Huang FL; Program of Developmental Neurobiology, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, United States., Hayata-Takano A; Laboratory of Molecular Neuropharmacology, Graduate School of Pharmaceutical Sciences, Osaka University, Suita, Japan.; Department of Pharmacology, Graduate School of Dentistry, Osaka University, Suita, Japan.; United Graduate School of Child Development, Osaka University, Kanazawa University, Hamamatsu University School of Medicine, Chiba University and University of Fukui, Suita, Japan., Hashimoto H; Laboratory of Molecular Neuropharmacology, Graduate School of Pharmaceutical Sciences, Osaka University, Suita, Japan.; United Graduate School of Child Development, Osaka University, Kanazawa University, Hamamatsu University School of Medicine, Chiba University and University of Fukui, Suita, Japan.; Division of Bioscience, Institute for Datability Science, Osaka University, Suita, Japan.; Transdimensional Life Imaging Division, Institute for Open and Transdisciplinary Research Initiatives, Osaka University, Suita, Japan.; Department of Molecular Pharmaceutical Science, Graduate School of Medicine, Osaka University, Suita, Japan., Tamada K; RIKEN Brain Science Institute, Wako, Japan.; Department of Physiology and Cell Biology, Kobe University School of Medicine, Kobe, Japan., Takumi T; RIKEN Brain Science Institute, Wako, Japan.; Department of Physiology and Cell Biology, Kobe University School of Medicine, Kobe, Japan., Kasahara T; Laboratory for Molecular Dynamics of Mental Disorders, RIKEN Center for Brain Science, Wako, Japan.; Institute of Biology and Environmental Sciences, Carl von Ossietzky University of Oldenburg, Oldenburg, Germany., Kato T; Laboratory for Molecular Dynamics of Mental Disorders, RIKEN Center for Brain Science, Wako, Japan.; Department of Psychiatry and Behavioral Science, Juntendo University Graduate School of Medicine, Tokyo, Japan., Graef IA; Department of Pathology, Stanford University School of Medicine, Stanford, United States., Crabtree GR; Department of Pathology, Stanford University School of Medicine, Stanford, United States., Asaoka N; Department of Pharmacology, Kyoto Prefectural University of Medicine, Kyoto, Japan., Hatakama H; Department of Molecular Pharmacology, Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto, Japan., Kaneko S; Department of Molecular Pharmacology, Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto, Japan., Kohno T; Department of Biomedical Science, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Japan., Hattori M; Department of Biomedical Science, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Japan., Hoshiba Y; Laboratory of Medical Neuroscience, Institute for Molecular and Cellular Regulation, Gunma University, Maebashi, Japan., Miyake R; Laboratory for Multi-scale Biological Psychiatry, RIKEN Center for Brain Science, Wako, Japan., Obi-Nagata K; Laboratory for Multi-scale Biological Psychiatry, RIKEN Center for Brain Science, Wako, Japan., Hayashi-Takagi A; Laboratory of Medical Neuroscience, Institute for Molecular and Cellular Regulation, Gunma University, Maebashi, Japan.; Laboratory for Multi-scale Biological Psychiatry, RIKEN Center for Brain Science, Wako, Japan., Becker LJ; Institut des Neurosciences Cellulaires et Intégratives, Centre National de la Recherche Scientifique, Université de Strasbourg, Strasbourg, France., Yalcin I; Institut des Neurosciences Cellulaires et Intégratives, Centre National de la Recherche Scientifique, Université de Strasbourg, Strasbourg, France., Hagino Y; Addictive Substance Project, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan., Kotajima-Murakami H; Addictive Substance Project, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan., Moriya Y; Addictive Substance Project, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan., Ikeda K; Addictive Substance Project, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan., Kim H; Department of Biological Sciences, College of Natural Sciences, Seoul National University, Seoul, Republic of Korea.; Department of Biomedical Engineering, Johns Hopkins School of Medicine, Baltimore, United States., Kaang BK; Department of Biological Sciences, College of Natural Sciences, Seoul National University, Seoul, Republic of Korea.; Center for Cognition and Sociality, Institute for Basic Science (IBS), Daejeon, Republic of Korea., Otabi H; College of Agriculture, Ibaraki University, Ami, Japan.; United Graduate School of Agricultural Science, Tokyo University of Agriculture and Technology, Fuchu, Japan., Yoshida Y; College of Agriculture, Ibaraki University, Ami, Japan., Toyoda A; College of Agriculture, Ibaraki University, Ami, Japan.; United Graduate School of Agricultural Science, Tokyo University of Agriculture and Technology, Fuchu, Japan.; Ibaraki University Cooperation between Agriculture and Medical Science (IUCAM), Ibaraki, Japan., Komiyama NH; Genes to Cognition Program, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom.; Simons Initiative for the Developing Brain, Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom., Grant SGN; Genes to Cognition Program, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom.; Simons Initiative for the Developing Brain, Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom., Ida-Eto M; Department of Developmental and Regenerative Medicine, Mie University, Graduate School of Medicine, Tsu, Japan., Narita M; Department of Developmental and Regenerative Medicine, Mie University, Graduate School of Medicine, Tsu, Japan., Matsumoto KI; Department of Biosignaling and Radioisotope Experiment, Interdisciplinary Center for Science Research, Organization for Research and Academic Information, Shimane University, Izumo, Japan., Okuda-Ashitaka E; Department of Biomedical Engineering, Osaka Institute of Technology, Osaka, Japan., Ohmori I; Department of Physiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan., Shimada T; Child Brain Project, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan., Yamagata K; Child Brain Project, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan., Ageta H; Division for Therapies Against Intractable Diseases, Center for Medical Science, Fujita Health University, Toyoake, Japan., Tsuchida K; Division for Therapies Against Intractable Diseases, Center for Medical Science, Fujita Health University, Toyoake, Japan., Inokuchi K; Research Center for Idling Brain Science, University of Toyama, Toyama, Japan.; Department of Biochemistry, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, Japan.; Core Research for Evolutionary Science and Technology (CREST), Japan Science and Technology Agency (JST), University of Toyama, Toyama, Japan., Sassa T; Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan., Kihara A; Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan., Fukasawa M; Department of Anatomy II, Fujita Health University School of Medicine, Toyoake, Japan., Usuda N; Department of Anatomy II, Fujita Health University School of Medicine, Toyoake, Japan., Katano T; Department of Medical Chemistry, Kansai Medical University, Hirakata, Japan., Tanaka T; Department of Developmental Medical Sciences, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan., Yoshihara Y; Laboratory for Systems Molecular Ethology, RIKEN Center for Brain Science, Wako, Japan., Igarashi M; Department of Neurochemistry and Molecular Cell Biology, School of Medicine, and Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan.; Transdiciplinary Research Program, Niigata University, Niigata, Japan., Hayashi T; Biomedical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Japan., Ishikawa K; Institute of Life and Environmental Sciences, University of Tsukuba, Tsukuba, Japan.; Graduate School of Science and Technology, University of Tsukuba, Tsukuba, Japan., Yamamoto S; Integrated Technology Research Laboratories, Pharmaceutical Research Division, Takeda Pharmaceutical Company, Ltd, Fujisawa, Japan., Nishimura N; Integrated Technology Research Laboratories, Pharmaceutical Research Division, Takeda Pharmaceutical Company, Ltd, Fujisawa, Japan., Nakada K; Institute of Life and Environmental Sciences, University of Tsukuba, Tsukuba, Japan.; Graduate School of Science and Technology, University of Tsukuba, Tsukuba, Japan., Hirotsune S; Department of Genetic Disease Research, Osaka City University Graduate School of Medicine, Osaka, Japan., Egawa K; Department of Pediatrics, Hokkaido University Graduate School of Medicine, Sapporo, Japan., Higashisaka K; Laboratory of Toxicology and Safety Science, Graduate School of Pharmaceutical Sciences, Osaka University, Suita, Japan., Tsutsumi Y; Laboratory of Toxicology and Safety Science, Graduate School of Pharmaceutical Sciences, Osaka University, Suita, Japan., Nishihara S; Glycan & Life Systems Integration Center (GaLSIC), Soka University, Tokyo, Japan., Sugo N; Graduate School of Frontier Biosciences, Osaka University, Suita, Japan., Yagi T; Graduate School of Frontier Biosciences, Osaka University, Suita, Japan., Ueno N; Laboratory of Morphogenesis, National Institute for Basic Biology, Okazaki, Japan., Yamamoto T; Division of Biophysics and Neurobiology, National Institute for Physiological Sciences, Okazaki, Japan., Kubo Y; Division of Biophysics and Neurobiology, National Institute for Physiological Sciences, Okazaki, Japan., Ohashi R; Laboratory of Neuronal Cell Biology, National Institute for Basic Biology, Okazaki, Japan.; Department of Basic Biology, SOKENDAI (Graduate University for Advanced Studies), Okazaki, Japan.; Exploratory Research Center on Life and Living Systems (ExCELLS), National Institutes of Natural Sciences, Okazaki, Japan., Shiina N; Laboratory of Neuronal Cell Biology, National Institute for Basic Biology, Okazaki, Japan.; Department of Basic Biology, SOKENDAI (Graduate University for Advanced Studies), Okazaki, Japan.; Exploratory Research Center on Life and Living Systems (ExCELLS), National Institutes of Natural Sciences, Okazaki, Japan., Shimizu K; Department of Biological Sciences, School of Science, The University of Tokyo, Tokyo, Japan., Higo-Yamamoto S; Healthy Food Science Research Group, Cellular and Molecular Biotechnology Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Japan., Oishi K; Healthy Food Science Research Group, Cellular and Molecular Biotechnology Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Japan.; Department of Applied Biological Science, Graduate School of Science and Technology, Tokyo University of Science, Noda, Japan.; Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Japan.; School of Integrative and Global Majors (SIGMA), University of Tsukuba, Tsukuba, Japan., Mori H; Department of Molecular Neuroscience, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, Japan., Furuse T; Mouse Phenotype Analysis Division, Japan Mouse Clinic, RIKEN BioResource Research Center (BRC), Tsukuba, Japan., Tamura M; Mouse Phenotype Analysis Division, Japan Mouse Clinic, RIKEN BioResource Research Center (BRC), Tsukuba, Japan., Shirakawa H; Department of Molecular Pharmacology, Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto, Japan., Sato DX; Division of Systems Medical Science, Center for Medical Science, Fujita Health University, Toyoake, Japan.; Graduate School of Life Sciences, Tohoku University, Sendai, Japan., Inoue YU; Department of Biochemistry and Cellular Biology, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Kodaira, Japan., Inoue T; Department of Biochemistry and Cellular Biology, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Kodaira, Japan., Komine Y; Young Researcher Support Group, Research Enhancement Strategy Office, National Institute for Basic Biology, National Institute of Natural Sciences, Okazaki, Japan.; Division of Brain Biology, National Institute for Basic Biology, Okazaki, Japan., Yamamori T; Division of Brain Biology, National Institute for Basic Biology, Okazaki, Japan.; Laboratory for Molecular Analysis of Higher Brain Function, RIKEN Center for Brain Science, Wako, Japan., Sakimura K; Department of Cellular Neurobiology, Brain Research Institute, Niigata University, Niigata, Japan.; Department of Animal Model Development, Brain Research Institute, Niigata University, Niigata, Japan., Miyakawa T; Division of Systems Medical Science, Center for Medical Science, Fujita Health University, Toyoake, Japan.

Publikováno v: ELife [Elife] 2024 Mar 26; Vol. 12. Date of Electronic Publication: 2024 Mar 26.

Mitochondria Play Essential Roles in Intracellular Protection against Oxidative Stress-Which Molecules among the ROS Generated in the Mitochondria Can Escape the Mitochondria and Contribute to Signal Activation in Cytosol?

Autor: Masuda D; Department of Space Environmental Medicine, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima 890-8544, Kagoshima, Japan.; Utilization & Engineering Department, Japan Manned Space Systems Corporation, 2-1-6 Tsukuba, Tsukuba 305-0047, Ibaraki, Japan., Nakanishi I; Quantum RedOx Chemistry Team, Institute for Quantum Life Science (iQLS), Quantum Life and Medical Science Directorate (QLMS), National Institutes for Quantum Science and Technology (QST), 4-9-1 Anagawa, Inage-ku, Chiba 263-8555, Japan., Ohkubo K; Institute for Advanced Co-Creation Studies, Open and Transdisciplinary Research Initiatives, Osaka University, Suita 565-0871, Japan., Ito H; Quantum RedOx Chemistry Team, Institute for Quantum Life Science (iQLS), Quantum Life and Medical Science Directorate (QLMS), National Institutes for Quantum Science and Technology (QST), 4-9-1 Anagawa, Inage-ku, Chiba 263-8555, Japan.; Department of Maxillofacial Radiology, Field of Oncology, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima 890-8544, Kagoshima, Japan., Matsumoto KI; Quantitative RedOx Sensing Group, Department of Radiation Regulatory Science Research, Institute for Radiological Science (NIRS), Quantum Life and Medical Science Directorate (QLMS), National Institutes for Quantum Science and Technology (QST), 4-9-1 Anagawa, Inage-ku, Chiba 263-8555, Japan., Ichikawa H; Department of Medical Life Systems, Graduate School of Life and Medical Sciences, Doshisha University, Kyoto 610-0394, Kyoto, Japan., Chatatikun M; School of Allied Health Sciences, Walailak University, Thasala, Nakhon Si Thammarat 80161, Thailand.; Center of Excellence Research for Melioidosis and Microorganisms, Walailak University, Thasala, Nakhon Si Thammarat 80161, Thailand., Klangbud WK; School of Allied Health Sciences, Walailak University, Thasala, Nakhon Si Thammarat 80161, Thailand.; Center of Excellence Research for Melioidosis and Microorganisms, Walailak University, Thasala, Nakhon Si Thammarat 80161, Thailand., Kotepui M; School of Allied Health Sciences, Walailak University, Thasala, Nakhon Si Thammarat 80161, Thailand., Imai M; Regenerative Medicine and Cell Design Research Facility, School of Allied Health Sciences, Kitasato University, 1-15-1 Kitasato, Sagamihara 252-0373, Kanagawa, Japan.; Department of Molecular Diagnostics, School of Allied Health Sciences, Kitasato University, 1-15-1 Kitasato, Sagamihara 252-0373, Kanagawa, Japan., Kawakami F; Regenerative Medicine and Cell Design Research Facility, School of Allied Health Sciences, Kitasato University, 1-15-1 Kitasato, Sagamihara 252-0373, Kanagawa, Japan.; Department of Regulation Biochemistry, Kitasato University Graduate School of Medical Sciences, 1-15-1 Kitasato, Sagamihara 252-0373, Kanagawa, Japan.; Department of Health Administration, School of Allied Health Sciences, Kitasato University, 1-15-1 Kitasato, Sagamihara 252-0373, Kanagawa, Japan., Kubo M; Regenerative Medicine and Cell Design Research Facility, School of Allied Health Sciences, Kitasato University, 1-15-1 Kitasato, Sagamihara 252-0373, Kanagawa, Japan.; Division of Microbiology, Kitasato University School of Allied Health Sciences, 1-15-1 Kitasato, Minami-ku, Sagamihara 252-0373, Kanagawa, Japan.; Department of Environmental Microbiology, Graduate School of Medical Sciences, Kitasato University, 1-15-1 Kitasato, Minami-ku, Sagamihara 252-0373, Kanagawa, Japan., Matsui H; Division of Gastroenterology, Graduate School of Comprehensive Human Science, University of Tsukuba, Tsukuba 305-8575, Ibaraki, Japan., Tangpong J; School of Allied Health Sciences, Walailak University, Thasala, Nakhon Si Thammarat 80161, Thailand.; Research Excellence Center for Innovation and Health Products (RECIHP), School of Allied Health Sciences, Walailak University, Thasala, Nakhon Si Thammarat 80160, Thailand., Ichikawa T; Regenerative Medicine and Cell Design Research Facility, School of Allied Health Sciences, Kitasato University, 1-15-1 Kitasato, Sagamihara 252-0373, Kanagawa, Japan.; Department of Molecular Diagnostics, School of Allied Health Sciences, Kitasato University, 1-15-1 Kitasato, Sagamihara 252-0373, Kanagawa, Japan., Ozawa T; Nihon Pharmaceutical University, 10281 Komuro, Ina-machi, Kitaadachi-gun, Saitama 362-0806, Saitama, Japan., Yen HC; Department of Medical Biotechnology and Laboratory Science, College of Medicine, Chang Gung University, Taoyuan 33302, Taiwan.; Department of Nephrology, Chang Gung Memorial Hospital at Linkou, Taoyuan 33305, Taiwan., St Clair DK; Department of Toxicology and Cancer Biology, University of Kentucky College of Medicine, Lexington, KY 40536, USA., Indo HP; Department of Maxillofacial Radiology, Field of Oncology, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima 890-8544, Kagoshima, Japan., Majima HJ; Department of Space Environmental Medicine, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima 890-8544, Kagoshima, Japan.; Department of Maxillofacial Radiology, Field of Oncology, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima 890-8544, Kagoshima, Japan.; School of Allied Health Sciences, Walailak University, Thasala, Nakhon Si Thammarat 80161, Thailand.; Research Excellence Center for Innovation and Health Products (RECIHP), School of Allied Health Sciences, Walailak University, Thasala, Nakhon Si Thammarat 80160, Thailand.

Publikováno v: Biomolecules [Biomolecules] 2024 Jan 19; Vol. 14 (1). Date of Electronic Publication: 2024 Jan 19.

Tenascin-X is increased with decreased expression of miR-378a-5p and miR-486-5p in mice fed a methionine-choline-deficient diet that induces hepatic fibrosis.

Autor: Matsumoto KI; Department of Biosignaling and Radioisotope Experiment, Interdisciplinary Center for Science Research, Head Office for Research and Academic Information, Shimane University, 89-1 Enya-cho, Izumo 693-8501, Japan., Higuchi T; Laboratory of Molecular Biology, Science Research Center, Kochi Medical School, Kochi University, Oko-cho, Kohasu, Nankoku 783-8505, Japan., Umeki M; Laboratory of Molecular Biology, Science Research Center, Kochi Medical School, Kochi University, Oko-cho, Kohasu, Nankoku 783-8505, Japan., Ono M; Division of Innovative Medicine for Hepatobiliary & Pancreatology, Faculty of Medicine, Kagawa University, 1750-1 Ikenobe, Miki-cho, Kita-gun, Kagawa 761-0793, Japan., Sakamoto S; Laboratory of Molecular Biology, Science Research Center, Kochi Medical School, Kochi University, Oko-cho, Kohasu, Nankoku 783-8505, Japan.

Publikováno v: Biomedical research (Tokyo, Japan) [Biomed Res] 2024; Vol. 45 (2), pp. 67-76.