A Novel Hypomorphic Apex1 Mouse Model Implicates Apurinic/Apyrimidinic Endonuclease 1 in Oxidative DNA Damage Repair in Gastric Epithelial Cells.

Autor: Rios-Covian D; Center for Veterinary Sciences and Comparative Medicine, Division of Comparative Pathology and Medicine, Department of Pathology, University of California, San Diego, La Jolla, California, USA., Butcher LD; Division of Gastroenterology, Department of Medicine, University of California, San Diego, La Jolla, California, USA., Ablack AL; Division of Gastroenterology, Department of Medicine, University of California, San Diego, La Jolla, California, USA., den Hartog G; Division of Gastroenterology, Department of Medicine, University of California, San Diego, La Jolla, California, USA., Matsubara MT; Division of Gastroenterology, Department of Medicine, University of California, San Diego, La Jolla, California, USA., Ly H; Division of Gastroenterology, Department of Medicine, University of California, San Diego, La Jolla, California, USA., Oates AW; Center for Veterinary Sciences and Comparative Medicine, Division of Comparative Pathology and Medicine, Department of Pathology, University of California, San Diego, La Jolla, California, USA., Xu G; Center for Computational Biology & Bioinformatics, Department of Medicine, University of California, San Diego, La Jolla, California, USA., Fisch KM; Center for Computational Biology & Bioinformatics, Department of Medicine, University of California, San Diego, La Jolla, California, USA., Ahrens ET; Department of Radiology, University of California, San Diego, La Jolla, California, USA., Toden S; Molecular Stethoscope, Inc., San Diego, California, USA., Brown CC; Department of Pathology, College of Veterinary Medicine, University of Georgia, Athens, Georgia, USA., Kim K; La Jolla Institute for Immunology, La Jolla, California, USA., Le D; Center for Veterinary Sciences and Comparative Medicine, Division of Comparative Pathology and Medicine, Department of Pathology, University of California, San Diego, La Jolla, California, USA., Eckmann L; Division of Gastroenterology, Department of Medicine, University of California, San Diego, La Jolla, California, USA., Dhar B; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, Kentucky, USA., Izumi T; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, Kentucky, USA., Ernst PB; Center for Veterinary Sciences and Comparative Medicine, Division of Comparative Pathology and Medicine, Department of Pathology, University of California, San Diego, La Jolla, California, USA.; Division of Gastroenterology, Department of Medicine, University of California, San Diego, La Jolla, California, USA.; Department of Immunology, Chiba University, Chiba, Japan., Crowe SE; Division of Gastroenterology, Department of Medicine, University of California, San Diego, La Jolla, California, USA.

Publikováno v: Antioxidants & redox signaling [Antioxid Redox Signal] 2023 Jan; Vol. 38 (1-3), pp. 183-197. Date of Electronic Publication: 2022 Aug 29.