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Clinicians’ Real World Perceptions of Pre-Nephrectomy Diagnostic Biopsy Performance as a Driver of Reduction in Unnecessary Surgeries in Renal Tumors

Autor: Mats Sanden, Kristin Fahy, Lauren Augustine, E. Robert Wassman

Publikováno v: Journal of Kidney Cancer and VHL
Journal of Kidney Cancer and VHL, Vol 2, Iss 1, Pp 1-14 (2015)

Operative removal of oncocytomas is generally unnecessary, but not infrequent in the context of renal masses. The infrequent use of pre-nephrectomy biopsies is a function of historical limitations of histopathological differential diagnosis in this s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3533ff34f056d37037b0181d622d40f0
http://europepmc.org/articles/PMC5345514

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Development and validation of a microRNA-based diagnostic assay for classification of renal cell carcinomas

Autor: Mats Sanden, Yael Spector, Sofia Zilber, Eddie Fridman, Heather Mitchell, Yajue Huang, Iris Barshack, Eti Meiri, Shai Rosenwald, Orit Zion

Publikováno v: Molecular Oncology. 7:732-738

Renal cancers account for more than 3% of adult malignancies and cause more than 13,000 deaths per year in the US alone. The four most common types of kidney tumors include the malignant renal cell carcinomas; clear cell, papillary, chromophobe and t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::127d538e993545207518b35af5478190
https://doi.org/10.1016/j.molonc.2013.03.002

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A Second-Generation MicroRNA-Based Assay for Diagnosing Tumor Tissue Origin

Publikováno v: The Oncologist. 17:801-812

Background. Cancers of unknown primary origin (CUP) constitute 3%–5% (50,000 to 70,000 cases) of all newly diagnosed cancers per year in the United States. Including cancers of uncertain primary origin, the total number increases to 12%–15% (180,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09a29fb88930895688cc8aca2630112b
https://doi.org/10.1634/theoncologist.2011-0466

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Classification of the four main types of lung cancer using a microRNA-based diagnostic assay

Autor: Nir Dromi, Ranit Aharonov, Iris Barshack, Sima Benjamin, Irit Krivitsky, Ilanit Burnstein, Laurie Horowitz, Yajue Huang, Craig Thurm, J. Steve Hou, Michal Kushnir, Marluce Bibbo, Shlomit Gilad, Meora Feinmesser, Gila Lithwick-Yanai, Brianna St. Cyr, Hadas Gibori, Mats Sanden, Tina Bocker Edmonston

Publikováno v: The Journal of molecular diagnostics : JMD. 14(5)

For patients with primary lung cancer, accurate determination of the tumor type significantly influences treatment decisions. However, techniques and methods for lung cancer typing lack standardization. In particular, owing to limited tumor sample am

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6409b3f8e3ae915d139141cdf41b60a0
https://pubmed.ncbi.nlm.nih.gov/22749746

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Abstract 802: Development and validation of a microRNA-based diagnostic assay for the classification of renal cell tumors

Autor: Noga Yerushalmi, Eddie Fridman, Brianna St. Cyr, Sofia Zilber, Iris Barshack, Mats Sanden, Robert Wassman, Yael Spector, Yajue Huang, Hila Benjamin

Publikováno v: Cancer Research. 73:802-802

Background: Renal cancers account for more than 3% of adult malignancies and result in more than 13,000 deaths per year in the US alone. The four most common types of kidney tumors include the malignant renal cell carcinomas: clear cell, papillary an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7492b57e728f8ac072c196f5a97e0b6f
https://doi.org/10.1158/1538-7445.am2013-802

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Abstract 816: A novel microRNA-based test demonstrates 92% accuracy in the classification of metastatic tumors from patients diagnosed with carcinoma of unknown primary

Autor: Robert Wassman, George Fountzilas, Anna Goussia, Karin Ashkenazi, Nicholas Palidis, Danit Lebanony, Eti Meiri, Katerina Stoyianni, George Pentheroudakis, Mats Sanden, Vassiliki Malamou-Mitsi

Publikováno v: Cancer Research. 73:816-816

Background: Cancers of unknown primary origin (CUP) constitute 3%-5% (50,000 to 70,000 cases) of all newly diagnosed cancers per year in the United States. Including cancers of uncertain primary origin, the total number increases to 12%-15% (180,000

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::61afbeae6fd23488d7c9b3063c97ad10
https://doi.org/10.1158/1538-7445.am2013-816

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Disproportionate representation of unexpected cancer origins in CUP population evident through microRNA profiling

Autor: Eran Goren, Alexis Smith, Mats Sanden, Robert Wassman

Publikováno v: Journal of Clinical Oncology. 32:e22102-e22102

e22102 Background: MicroRNA profiling of tumors can accurately identify the cancer of origin in CUP patients. The distribution of cancers observed in CUP patients and can aid overall understanding ...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::32c6d85ceb55c75804feaa6b0a9fc6a2
https://doi.org/10.1200/jco.2014.32.15_suppl.e22102

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Observational study of real world clinical performance of microrna molecular profiling for cancer of unknown primary (CUP)

Autor: Yael Spector, Robert Wassman, Hila Benjamin, Mats Sanden, Karin Ashkenazi, Eran Goren

Publikováno v: Journal of Clinical Oncology. 31:e22173-e22173

e22173 Background: Molecular profiling of CUP may effectively identify the underlying tumor type and potentially influence treatment decisions and outcomes. A microRNA (miR) array has been shown in concordance studies at leading academic centers to p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5727722d6633d2191144521a1855dbf1
https://doi.org/10.1200/jco.2013.31.15_suppl.e22173

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