Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Mats Lake"'
Publikováno v:
Journal of Biological Chemistry. 272:4804-4813
A soluble form of the insulin-like growth factor II/mannose 6-phosphate receptor (sIGF-II/MPR) is present in fetal bovine serum and carries mature 7.5-kDa insulin-like growth factor II (IGF-II) and at least 12 different high molecular weight (Mr) IGF
Autor:
Steen Gammeltoft, Gisela Haselbacher, Finn Cilius Nielsen, Jan Christiansen, Mats Lake, Mette Grønborg
Publikováno v:
Molecular and Cellular Endocrinology. 93:87-95
In the present study we have analysed the expression of insulin-like growth factor II (IGF-II) in the human rhabdomyosarcoma cell line IN157. IN157 cells express high levels of three IGF-II mRNAs of 6.0 kb, 4.8 kb and 4.2 kb. In contrast, normal skel
Autor:
Göran Forsberg, Katarina Ljungström, Mats Lake, Anders Haegerstrand, Gunnar Kratz, Magnus Gidlund
Publikováno v:
Experimental Cell Research. 202:381-385
The present report describes the mitogenic effect of recombinant IGF-2 on cultured human keratinocytes and fibroblasts compared to that of IGF-1. Furthermore, the modulating effect of a recently expressed recombinant form of placental-derived IGF-bin
Autor:
Barbro Baastrup, Helena Rondahl, Gunnar Pohl, Mats Lake, Maris Hartmanis, Erik Holmgren, Göran Forsberg
Publikováno v:
Journal of Protein Chemistry. 11:201-211
Different enzymatic methods for cleavage of recombinant fusion proteins were compared. To find an efficient cleavage method, five different fusion proteins were produced. The fusion proteins differed only in the linker region between the fusion partn
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 74:447-452
The erythroid-potentiating effects of biosynthetic human insulin-like growth factor-I (IGF-I) and IGF-II were evaluated and compared in serum-free cultures of human marrow erythroid progenitors. IGF-I and IGF-II enhanced the in vitro growth of relati
Autor:
Ann-Mari Svennerholm, Bjorn Lowenadler, Anders R. Karlstrom, Annette Elmblad, Jan Holmgren, Erik Holmgren, Mats Lake
Publikováno v:
FEMS Microbiology Letters. 82:271-278
A recombinant fusion protein consisting of native Escherichia coli heat-stable enterotoxin (STa) and a dimer of a synthetic IgG-binding fragment (ZZ), derived from Staphylococus aureus protein A was produced in E. coli . The fusion protein (ZZSTa) wa
Publikováno v:
Biology of the neonate. 71(4)
The organ distribution of intravenously injected 125I-IGF-I at a dose of 2–4 × 106 cpm or 5–10 ng/animal was studied in 10-to 12-day-old Sprague-Dawley rats at 5 and 30 min after injection. Results of the study suggest that, although the main po
Autor:
Mats Lake, Anthony F Philipps, David M. McCracken, Gary G. Anderson, R. K. Rao, Otakar Koldovsky
Publikováno v:
Pediatric research. 37(5)
Milk-borne insulin-like growth factors I and II (IGF-I and -II) may be of importance in the differentiation of the gastrointestinal tract of the suckling. To test this hypothesis, 10- to 11-d-old suckling rats were given via an orogastric tube 125I-I
Publikováno v:
Scandinavian journal of plastic and reconstructive surgery and hand surgery. 28(2)
Insulin like growth factor (IGF) 1 and 2 which are present and actively synthesised in the wound fluid stimulate several cell types involved in the process of wound healing. To investigate the role of IGF-1 and 2 and in addition, the association betw
Publikováno v:
Journal of cellular physiology. 157(1)
The effect of biosynthetic human insulin-like growth factor I (IGF-I) and IGF-II on the in vitro growth of human marrow myeloid progenitors in the presence of recombinant human granulocyte colony stimulating factor (rhG-CSF), granulocyte-macrophage C