Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Mats Inganäs"'
Publikováno v:
Analytical and Bioanalytical Chemistry. 399:1601-1611
Recombinant therapeutic antibodies have shown a great potential in the treatment of several severe medical conditions such as cancer and autoimmune diseases. Glycosylation plays a critical role in biological activity and immunogenic properties of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8d4dfd8575168bd2f19475aabee2245
https://doi.org/10.1007/s00216-010-4469-y
https://doi.org/10.1007/s00216-010-4469-y
Autor:
Sigrid Klaar, Lars Larsson, Jenny Andersson, Göran Carlsson, John Ohd, Jonas Bergh, Bengt Gustavsson, Jan Nilsson, Mats Inganäs, Lars Holmberg, C-M. Rudenstam
Publikováno v:
Annals of Oncology. 16:743-748
Background: TP53 has been described as a prognostic factor in many malignancies, including breast cancer. Whether it also might be a predictive factor with reference to chemo- and endocrine therapy is more controversial. Patients and methods: We inve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::910f23d0cf1810ae88fab2b9570d14e5
https://doi.org/10.1093/annonc/mdi150
https://doi.org/10.1093/annonc/mdi150
Publikováno v:
International Journal of Cancer. 79:376-383
The p53mutational status of 226 representative primary breast cancer samples, derived from a population-based cohort, was analyzed using cDNA-based sequencing. The results were compared with those obtained with immunohistochemistry (IHC) on microwave
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ad7d7c7634c3eed2bdfe1152097bcbb
https://doi.org/10.1002/(sici)1097-0215(19980821)79:4<376::aid-ijc12>3.0.co
https://doi.org/10.1002/(sici)1097-0215(19980821)79:4<376::aid-ijc12>3.0.co
Autor:
Ann-Kristin Honerud, Mats Inganäs, Ann Eckersten, Gunnar Ekstrand, Helene Derand, Per Andersson, Gunnar Thorsén, Tobias Söderman, Gérald Jesson
Publikováno v:
Clinical Chemistry. 51:1985-1987
Reducing the size of reaction volumes in immunodiagnostic procedures can reduce not only reagent cost but also analysis time. With reduced sample and reagent volumes and use of a flow-through mode, reactions reach completion rapidly, potentially decr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ba7842704abdaf29c372f3afde0016d
https://doi.org/10.1373/clinchem.2005.053181
https://doi.org/10.1373/clinchem.2005.053181
Autor:
Jonas Bergh, Mats Inganäs, Torbjörn Norberg, Tomas Jansson, S Sjogren, Anders Lindgren, Lars Holmberg
Publikováno v:
Journal of Clinical Oncology. 13:2745-2751
PURPOSE AND METHODS Primary breast cancer tumors without axillary metastases from 206 consecutive patients in a population-based cohort were investigated with regard to the presence of an intact p53 gene using a cDNA-based sequencing method. Clinical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3d6b49f08a2d57510b18b631aff627e
https://doi.org/10.1200/jco.1995.13.11.2745
https://doi.org/10.1200/jco.1995.13.11.2745
Publikováno v:
International Journal of Oncology.
Previous reports have claimed that antibodies to mutated p53 protein indicate poor outcome in malignant disease. The mechanism behind this highly specific process is unclear, although it has been claimed that certain DNA alterations are prone to indu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcac611a10286f2c9cb4d42cbb5bdcb3
https://doi.org/10.3892/ijo.19.3.501
https://doi.org/10.3892/ijo.19.3.501
Publikováno v:
Micro Total Analysis Systems 2001 ISBN: 9789401038935
The traditional approach to identify/analyze proteins in a proteomics perspective is to separate crude samples of proteins by 2-D electrophoresis prior to further processing and identification of individual proteins by, for example, MALDI-MS. The pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af27017b46a85e70f9190931fe6f6ab8
https://doi.org/10.1007/978-94-010-1015-3_33
https://doi.org/10.1007/978-94-010-1015-3_33
Autor:
Ulf Kressner, Solveig Eriksson, Tomas Hultman, Mats Inganäs, Ann Eckersten, Fariba Sabounchi, Esfir Löfman, Nigel Eric Tooke, Gudrun Lindmark, Sara Byding, Anneli Jorsback
Publikováno v:
Clinical chemistry. 46(10)
Background: The enzymatic mutation detection (EMD) assay uses the bacteriophage resolvase T4 endonuclease VII, which cleaves preformed heteroduplex molecules at mismatch sites, forming two shorter fragments that can be resolved by gel electrophoresis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c240154502cde6e2f6c6f4b64460dee2
https://pubmed.ncbi.nlm.nih.gov/11017933
https://pubmed.ncbi.nlm.nih.gov/11017933
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 16(2)
PURPOSE To investigate the prognostic and predictive value of c-erbB-2 overexpression in breast cancer in relation to other prognostic markers. PATIENTS AND METHODS Paraffin-embedded tumors from 315 consecutive primary breast cancer patients were scr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b1dafe0dee66b6af070310d80c33746
https://pubmed.ncbi.nlm.nih.gov/9469329
https://pubmed.ncbi.nlm.nih.gov/9469329
Autor:
Mats Inganäs, Jonas Bergh, Lars Holmberg, Hans Nordgren, Anders Lindgren, Torbjörn Norberg, S Sjogren
Publikováno v:
Journal of the National Cancer Institute. 88(3-4)
Background: Mutations in the p53 tumor suppressor gene (also known as TP53) have been detected in a wide variety of human cancers. In breast cancer, the presence of p53 gene alterations has been associated with worse prognosis. Purpose: We compared a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7be7a28ff98f44f74ca276cc5338645
https://pubmed.ncbi.nlm.nih.gov/8632491
https://pubmed.ncbi.nlm.nih.gov/8632491