Zobrazeno 1 - 10
of 180
pro vyhledávání: '"Mats, Ulfendahl"'
Publikováno v:
Neurobiology of Disease, Vol 29, Iss 1, Pp 14-21 (2008)
Cochlear implant surgery is currently the therapy of choice for profoundly deaf patients. However, the functionality of cochlear implants depends on the integrity of the auditory spiral ganglion neurons. This study assesses the combined efficacy of t
Externí odkaz:
https://doaj.org/article/2dca84f7981743e1b75dd7e45d63cece
Autor:
Jun Maruyama, Takahiko Yamagata, Mats Ulfendahl, Göran Bredberg, Richard A. Altschuler, Josef M. Miller
Publikováno v:
Neurobiology of Disease, Vol 25, Iss 2, Pp 309-318 (2007)
Based on in vitro studies, it is hypothesized that neurotrophic factor deprivation following deafferentation elicits an oxidative state change in the deafferented neuron and the formation of free radicals that then signal cell death pathways. This pa
Externí odkaz:
https://doaj.org/article/c3093baa5a714b4891cc093899b382e8
Publikováno v:
Neurobiology of Disease, Vol 18, Iss 1, Pp 184-192 (2005)
Neuronal tissue transplantation is a potential way to replace degenerated spiral ganglion neurons (SGNs) since these cells cannot regenerate in adult mammals. To investigate whether nerve growth factor (NGF) can stimulate neurite outgrowth from impla
Externí odkaz:
https://doaj.org/article/2ed0414aaf9b432bba20f549ba432f8a
Autor:
Francis Collins, Alain Beaudet, Ruxandra Draghia-Akli, Peter Gruss, John Savill, André Syrota, Alice Dautry, Mats Ulfendahl, Mark Walport, James Onken, Roger I Glass
Publikováno v:
The Lancet Global Health, Vol 1, Iss 2, Pp e64-e65 (2013)
Externí odkaz:
https://doaj.org/article/059878b3a0b349fab141c18265581365
Autor:
Suvarna Dash-Wagh, Stefan Jacob, Staffan Lindberg, Anders Fridberger, Ülo Langel, Mats Ulfendahl
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 1, Iss C (2012)
RNA interference (RNAi) using short interfering RNA (siRNA) is an attractive therapeutic approach for treatment of dominant-negative mutations. Some rare missense dominant-negative mutations lead to congenital-hearing impairments. A variety of viral
Externí odkaz:
https://doaj.org/article/ac4dfda56966494cad74e7ea337a818e
Publikováno v:
Journal of Controlled Release
For patients with profound hearing loss a cochlear implant (CI) is the only treatment today. The function of a CI depends in part of the function and survival of the remaining spiral ganglion neurons (SGN). It is well known from animal models that in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44d2ca710c1b7725f10c9ffd3be4c4e1
http://europepmc.org/articles/PMC5819869
http://europepmc.org/articles/PMC5819869
Autor:
Anders R Hellström, Brenda Watt, Shahrzad Shirazi Fard, Danièle Tenza, Paula Mannström, Kristina Narfström, Björn Ekesten, Shosuke Ito, Kazumasa Wakamatsu, Jimmy Larsson, Mats Ulfendahl, Klas Kullander, Graça Raposo, Susanne Kerje, Finn Hallböök, Michael S Marks, Leif Andersson
Publikováno v:
PLoS Genetics, Vol 7, Iss 9, p e1002285 (2011)
PMEL is an amyloidogenic protein that appears to be exclusively expressed in pigment cells and forms intralumenal fibrils within early stage melanosomes upon which eumelanins deposit in later stages. PMEL is well conserved among vertebrates, and alle
Externí odkaz:
https://doaj.org/article/421f79eca213475d87b146fc6194252f
Publikováno v:
Neurophysiology. 49:316-326
C57BL/6J mice develop age-related hearing loss (HL) early in life. The influence of aging and noise exposure on the number of presynaptic structures in inner hair cells of C57BL/6J mice has not been studied. We monitored auditory brainstem responses,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ac65cd557d1455fc2cdee37646080d2
https://doi.org/10.1007/s11062-018-9691-9
https://doi.org/10.1007/s11062-018-9691-9
Autor:
Mats Ulfendahl, Anette Fransson
Publikováno v:
Journal of Neuroscience Research. 95:869-875
Today a cochlear implant (CI) may significantly restore auditory function, even for people with a profound hearing loss. Because the efficacy of a CI is believed to depend mainly on the remaining population of spiral ganglion neurons (SGNs), it is im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a75e0eac586505af1b798888c8ba0d0d
https://doi.org/10.1002/jnr.23824
https://doi.org/10.1002/jnr.23824
Publikováno v:
Biophysical journal. 114(11)
The organization of the plasma membrane of cells in lipid domains affects the way the membrane interacts with the underlying protein skeleton, which in turn affects the lateral mobility of lipid and protein molecules in the membrane. Membrane fluidit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31f2d97d879bd7fbdcd73fbd749612f8
https://pubmed.ncbi.nlm.nih.gov/16603502
https://pubmed.ncbi.nlm.nih.gov/16603502