Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Matrix Metalloproteinase 9/metabolism"'
Autor:
Rabindra Tirouvanziam, Abdelwahed Chtarto, Kim Q. Do, Lijing Xin, Philippe Conus, Martine Cleusix, Audrey Goupil, Daniella Dwir, Paul Klauser, Liliane Tenenbaum, Raoul Jenni, Michel Cuenod, Jan Harry Cabungcal, Philipp S. Baumann, Basilio Giangreco, Pascal Steullet
Publikováno v:
Molecular psychiatry, vol. 25, no. 11, pp. 2889-2904
Molecular psychiatry, 25 (11
Molecular Psychiatry
Molecular psychiatry, 25 (11
Molecular Psychiatry
Various mechanisms involved in schizophrenia pathophysiology, such as dopamine dysregulation, glutamate/NMDA receptor dysfunction, neuroinflammation or redox imbalance, all appear to converge towards an oxidative stress “hub” affecting parvalbumi
Autor:
Benjamin Misselwitz, Martin Hausmann, Jean-Benoît Rossel, Stefania Fagagnini, Gerhard Rogler, Niko Beerenwinkel, Bruce Weder, Brian M. Lang, Christian Lutz, Anouk Hünerwadel
Publikováno v:
Scientific reports, vol. 7, no. 1, pp. 17678
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Scientific Reports, 7 (1)
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Scientific Reports, 7 (1)
Scientific Reports
Dysregulation of the immune response to microbiota is associated with inflammatory bowel disease (IBD), which can trigger intestinal fibrosis. MyD88 is a key component of microbiota signalling but its influence on intestinal fibrosis has not been cla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8e45e447b5914428033cacd0dd485ba
https://www.zora.uzh.ch/id/eprint/143601/
https://www.zora.uzh.ch/id/eprint/143601/
Autor:
Christelle Tissot, Candice Trocmé, Stephanie Carnesecchi, Julien Cachat, Karl-Heinz Krause, Sylvie Papacatzis, Christine Deffert, Rikard Holmdahl, Yves Donati, Vincent Braunersreuther, Jean-Claude Pache, Constance Barazzone-Argiroffo
Publikováno v:
The Journal of pathology
The Journal of Pathology, Vol. 235, No 1 (2015) pp. 65-78
The Journal of Pathology
JOURNAL OF PATHOLOGY
The Journal of Pathology, Vol. 235, No 1 (2015) pp. 65-78
The Journal of Pathology
JOURNAL OF PATHOLOGY
Reactive oxygen species (ROS) participate in the pathogenesis of emphysema. Among ROS-producing enzymes, NOX NADPH oxidases are thought to be responsible for tissue injury associated with several lung pathologies. To determine whether NOX2 and/or NOX
Autor:
Padamsey, Zahid, McGuinness, Lindsay, Bardo, Scott J., Reinhart, Marcia, Tong, Rudi, Hedegaard, Anne, Hart, Michael L., Emptage, Nigel J.
Publikováno v:
Padamsey, Z, McGuinness, L, Bardo, S J, Reinhart, M, Tong, R, Hedegaard, A, Hart, M L & Emptage, N J 2017, ' Activity-Dependent Exocytosis of Lysosomes Regulates the Structural Plasticity of Dendritic Spines ', Neuron, vol. 93, no. 1, pp. 132-146 . https://doi.org/10.1016/j.neuron.2016.11.013
Lysosomes have traditionally been viewed as degradative organelles, although a growing body of evidence suggests that they can function as Ca2+ stores. Here we examined the function of these stores in hippocampal pyramidal neurons. We found that back
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::05e00eaf185c3f01b546c041c8c7d96b
https://www.pure.ed.ac.uk/ws/files/138858385/Padamsey_Z_Activity_Dependent_Exocytosis....pdf
https://www.pure.ed.ac.uk/ws/files/138858385/Padamsey_Z_Activity_Dependent_Exocytosis....pdf
Autor:
Inga Bauer, Sébastien Lenglet, Fabrizio Montecucco, Sabine Steffens, Franco Patrone, Nicolas Vuilleumier, Graziano Pelli, Fabienne Burger, Nikolaos Stergiopulos, Alessandra Quercioli, Rodrigo A. Fraga-Silva, Rafaela F. da Silva, Maria Bertolotto, Irene Caffa, Franco Dallegri, Sara Vazquez Calvo, Robson A.S. Santos, Mathias Fabre, Alessio Nencioni, François Mach, Katia Galan, Alberto Ballestrero, Santina Bruzzone, Mirko Magnone, Giovanna Sociali
Publikováno v:
Thrombosis and Haemostasis; Vol 111
Thrombosis and Haemostasis, Vol. 111, No 2 (2014) pp. 308-322
Thrombosis and Haemostasis
Thrombosis and haemostasis
Thrombosis and Haemostasis, Vol. 111, No 2 (2014) pp. 308-322
Thrombosis and Haemostasis
Thrombosis and haemostasis
SummaryPharmacological treatments targeting CXC chemokines and the associated neutrophil activation and recruitment into atherosclerotic plaques hold promise for treating cardiovascular disorders. Therefore, we investigated whether FK866, a nicotinam
Autor:
Asita Sarrafzadeh, Karl Lothard Schaller, Peter Vajkoczy, Philippe Bijlenga, Natacha Turck, Yvan Gasche, Daniel Jiménez Bengualid, Jean-Christophe Copin
Publikováno v:
Neurological Research, Vol. 34, No 5 (2012) pp. 455-461
The pathogenesis of delayed cerebral ischemia (DCI) in aneurysmal subarachnoid hemorrhage (aSAH) is multi-factorial and not completely elucidated. Matrix metalloproteinase-9 (MMP-9) might participate in wall remodeling leading to luminal narrowing. T
Autor:
Alessandra Quercioli, Fabrizio Montecucco, Nicolas Vuilleumier, Thomas H. Schindler, Osman Ratib, Aurélien Thomas, Franco Dallegri, Vincent Braunersreuther, Maria Bertolotto, Giuseppe Cittadini, Sébastien Lenglet, François Mach, Christian Staub, Graziano Pelli, Giovanna Bianchi, Vito Pistoia, Katia Galan, Aldo Pende, Sabrina Pagano, Giorgio Luciano Viviani, Pascale Roux-Lombard
Publikováno v:
Thrombosis and Haemostasis; Vol 107
Thrombosis and Haemostasis
Thrombosis and Haemostasis, Vol. 107, No 1 (2012) pp. 124-39
Thrombosis and haemostasis
Thrombosis and Haemostasis
Thrombosis and Haemostasis, Vol. 107, No 1 (2012) pp. 124-39
Thrombosis and haemostasis
SummaryThe “blood vulnerability”, resulting from the complex balance between serum molecules and inflammatory cell atherosclerotic activities, is a major determinant in the evaluation of the “global patient cardiovascular vulnerability”. In t
Anti-Apolipoprotein A-1 auto-antibodies are active mediators of atherosclerotic plaque vulnerability
Autor:
Fabrizio Montecucco, Nicolas Vuilleumier, Pascale Roux-Lombard, Vincent Braunersreuther, Franco Dallegri, Graziano Pelli, Giovanni Spinella, Bianca Pane, François Mach, Eniko Veronika Kovari, Sébastien Lenglet, Domenico Palombo, Maria Bertolotto, Aldo Pende, Sabrina Pagano
Publikováno v:
ResearcherID
European Heart Journal, Vol. 32, No 4 (2011) pp. 412-21
European Heart Journal; Vol 32
European Heart Journal
European Heart Journal, Vol. 32, No 4 (2011) pp. 412-21
European Heart Journal; Vol 32
European Heart Journal
Aims Anti-Apolipoprotein A-1 auto-antibodies (anti-ApoA-1 IgG) represent an emerging prognostic cardiovascular marker in patients with myocardial infarction or autoimmune diseases associated with high cardiovascular risk. The potential relationship b
Autor:
Daniel Guldager Kring Rasmussen, Anthony Fenton, Morten A. Karsdal, Mark Jesky, Paul Cockwell, Signe Holmh Nielsen, Federica Genovese, Susanne Brix, Charles J. Ferro
Publikováno v:
Holm Nielsen, S, Guldager Kring Rasmussen, D, Brix, S, Fenton, A, Jesky, M, Ferro, C J, Karsdal, M, Genovese, F & Cockwell, P 2018, ' A novel biomarker of laminin turnover is associated with disease progression and mortality in chronic kidney disease ', PLOS ONE, vol. 13, no. 10, e0204239 . https://doi.org/10.1371/journal.pone.0204239
Nielsen, S H, Rasmussen, D G K, Brix, S, Fenton, A, Jesky, M, Ferro, C J, Karsdal, M, Genovese, F & Cockwell, P 2018, ' A novel biomarker of laminin turnover is associated with disease progression and mortality in chronic kidney disease ', PLOS ONE, vol. 13, no. 10, e0204239 . https://doi.org/10.1371/journal.pone.0204239
PLoS ONE
PLoS ONE, Vol 13, Iss 10, p e0204239 (2018)
Nielsen, S H, Rasmussen, D G K, Brix, S, Fenton, A, Jesky, M, Ferro, C J, Karsdal, M, Genovese, F & Cockwell, P 2018, ' A novel biomarker of laminin turnover is associated with disease progression and mortality in chronic kidney disease ', PLOS ONE, vol. 13, no. 10, e0204239 . https://doi.org/10.1371/journal.pone.0204239
PLoS ONE
PLoS ONE, Vol 13, Iss 10, p e0204239 (2018)
Background: Patients with chronic kidney disease (CKD) have increased risk of development of endstage renal disease (ESRD) and early mortality. Fibrosis is the central pathogenic process in CKD and is caused by dysregulated extracellular matrix (ECM)
Autor:
Vincent Braunersreuther, Claire Arnaud, Amanda E. I. Proudfoot, Sabine Steffens, François Mach, Fabienne Burger, Graziano Pelli
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology, Vol. 28, No 6 (2008) pp. 1090-6
Background— Atherosclerosis is a chronic inflammatory disease that represents the primary cause of death through coronary disease and stroke. Chemokines are known to play a crucial role in this disease by recruiting inflammatory leukocytes to the e