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In vivo and in vitro Characterization of a Partial Mu Opioid Receptor Agonist, NKTR-181, Supports Future Therapeutic Development.

Autor: Lee AS; Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, Los Angeles, CA, United States., Tiwari S; Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, Los Angeles, CA, United States., Bishop I; Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, Los Angeles, CA, United States., Matossian V; Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, Los Angeles, CA, United States., Romaneschi N; Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, Los Angeles, CA, United States., Miyazaki T; Nektar Therapeutics, San Francisco, CA, United States., VanderVeen L; Nektar Therapeutics, San Francisco, CA, United States., Zalevsky J; Nektar Therapeutics, San Francisco, CA, United States., DeFea K; KiloDalton Consulting, Orinda, CA, United States.; Division of Biomedical Sciences, School of Medicine, University of California, Riverside, Riverside, CA, United States., Cahill CM; Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, Los Angeles, CA, United States.; Brain Research Institute, University of California, Los Angeles, Los Angeles, CA, United States.; Shirley & Stefen Hatos Center for Neuropharmacology, University of California, Los Angeles, Los Angeles, CA, United States.; Jane & Terry Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, Los Angeles, CA, United States., Walwyn WM; Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, Los Angeles, CA, United States.; Brain Research Institute, University of California, Los Angeles, Los Angeles, CA, United States.; Shirley & Stefen Hatos Center for Neuropharmacology, University of California, Los Angeles, Los Angeles, CA, United States.; Jane & Terry Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, Los Angeles, CA, United States.

Publikováno v: Frontiers in pain research (Lausanne, Switzerland) [Front Pain Res (Lausanne)] 2021 Aug 23; Vol. 2, pp. 695962. Date of Electronic Publication: 2021 Aug 23 (Print Publication: 2021).