Metabolomic Analysis and Antiviral Screening of a Marine Algae Library Yield Jobosic Acid (2,5-Dimethyltetradecanoic Acid) as a Selective Inhibitor of SARS-CoV-2.

Autor: Matos-Hernández ML; Department of Pharmaceutical Sciences, School of Pharmacy, University of Puerto Rico-Medical Sciences Campus, San Juan, Puerto Rico 00935, United States., Samples R; Center for Mass Spectrometry, Smith College, Northampton, Massachusetts 01063, United States., Dyer G; Department of Pharmaceutical Sciences, School of Pharmacy, University of Puerto Rico-Medical Sciences Campus, San Juan, Puerto Rico 00935, United States., Casimir Montán VM; Department of Chemistry, Natural Sciences College, University of Puerto Rico-Rio Piedras Campus, San Juan, Puerto Rico 00925, United States., Morales-Colón CA; Department of Chemistry, Natural Sciences College, University of Puerto Rico-Rio Piedras Campus, San Juan, Puerto Rico 00925, United States., Salvino JM; The Wistar Institute, Philadelphia, Pennsylvania 19104, United States., Montaner LJ; The Wistar Institute, Philadelphia, Pennsylvania 19104, United States., Cassel JA; The Wistar Institute, Philadelphia, Pennsylvania 19104, United States., Messick TE; The Wistar Institute, Philadelphia, Pennsylvania 19104, United States., Tietjen I; The Wistar Institute, Philadelphia, Pennsylvania 19104, United States., Caro-Diaz EJE; Department of Pharmaceutical Sciences, School of Pharmacy, University of Puerto Rico-Medical Sciences Campus, San Juan, Puerto Rico 00935, United States.

Publikováno v: Journal of natural products [J Nat Prod] 2024 Jun 28; Vol. 87 (6), pp. 1513-1520. Date of Electronic Publication: 2024 May 23.