Aryl hydrocarbon receptor knockout accelerates PanIN formation and fibro-inflammation in a mutant Kras -driven pancreatic cancer model.

Autor: Walcheck MT; University of Wisconsin School of Medicine and Public Health, Department of Surgery, Division of Surgical Oncology, K4/747 CSC, 600 Highland Avenue, Madison, WI 53792., Schwartz PB; University of Wisconsin School of Medicine and Public Health, Department of Surgery, Division of Surgical Oncology, K4/747 CSC, 600 Highland Avenue, Madison, WI 53792., Carrillo ND; University of Wisconsin, McArdle Laboratory for Cancer Research, 1400 University Avenue, McArdle Research Building, Madison, WI, 53706., Matkowsky KA; University of Wisconsin School of Medicine and Public Health, Department of Pathology and Laboratory Medicine, L5/183 CSC, 600 Highland Avenue, Madison, WI 53792.; University of Wisconsin Carbone Cancer Center, Madison, WI 53705.; William S. Middleton Memorial Veterans Hospital, Madison, WI 53705., Nukaya M; University of Wisconsin School of Medicine and Public Health, Department of Surgery, Division of Surgical Oncology, K4/747 CSC, 600 Highland Avenue, Madison, WI 53792.; University of Wisconsin, McArdle Laboratory for Cancer Research, 1400 University Avenue, McArdle Research Building, Madison, WI, 53706., Bradfield CA; University of Wisconsin, McArdle Laboratory for Cancer Research, 1400 University Avenue, McArdle Research Building, Madison, WI, 53706., Ronnekleiv-Kelly SM; University of Wisconsin School of Medicine and Public Health, Department of Surgery, Division of Surgical Oncology, K4/747 CSC, 600 Highland Avenue, Madison, WI 53792.; University of Wisconsin, McArdle Laboratory for Cancer Research, 1400 University Avenue, McArdle Research Building, Madison, WI, 53706.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Feb 03. Date of Electronic Publication: 2023 Feb 03.