Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Matityahu Shaklai"'
Publikováno v:
International Journal of Laboratory Hematology. 33:645-650
Summary Introduction: Haemoglobin (Hb) quantification in whole blood is possible by various spectrophotometric methods. However, determination of low-level Hb in erythroid precursors or haemolytic plasma is inaccurate because of contribution from lig
Publikováno v:
Leukemia Research. 31:1115-1123
Chronic myelogenous leukemia (CML) is associated with the high TK activity chimeric protein BCR-ABL, known to contribute to cell tumorogenicity, resistance to apoptosis and differentiation. STI571, the TK inhibitor, is the current treatment for CML.
Publikováno v:
Biochemistry. 43:3899-3906
LDL oxidation plays a pivotal role in atherosclerosis. Excellular hemoglobin (Hb) is a trigger of LDL oxidation. By virtue of its ability to bind hemoglobin, haptoglobin (Hp) serves as an antioxidant. Oxidation of LDL by hemoglobin was analyzed to oc
Publikováno v:
Medical Microbiology and Immunology. 192:205-209
Human T lymphotropic virus type 1 (HTLV-1) is the etiological agent of adult T cell leukemia and HTLV-1-associated myelopathy/tropical spastic paraparesis. HTLV-1 infection in patients with B cell-type chronic lymphocytic leukemia (B-CLL) is rare and
Publikováno v:
British Journal of Cancer
It is now clear that angiogenesis and angiogenesis factors are important in the pathogenesis of haematological malignancies. High pretreatment levels of serum basic fibroblast growth factor have been shown to be associated with poor prognosis in pati
Publikováno v:
British Journal of Haematology. 113:400-406
A large proportion of B-chronic lymphocytic leukaemia (B-CLL) cells express the anti-apoptotic protein Bcl-2. Basic fibroblast growth factor (bFGF) has been shown to upregulate the expression of Bcl-2 in B-CLL cell lines. Vascular endothelial growth
Publikováno v:
European Journal of Haematology. 66:263-271
B-chronic lymphocytic leukemia (B-CLL) is a disease caused primarily by defects in the apoptosis mechanism. AN-9, a butyric acid (BA) derivative, is a potent differentiating and an anti-cancer drug that induces apoptosis in HL-60 cells. Herein we sho
Publikováno v:
Medical Oncology. 17:314-318
Preliminary reports involving a number of different kinds of tumors have indicated that microvessel quantification may be useful in predicting disease outcome. The aim of this study was to examine the relationship between microvessel density (MVD) as
Autor:
Gerhard Hunsmann, E Kott, Matityahu Shaklai, H Hannig, D Ron, C Gordon, B Shohat, W. Bodemer, L Rapaport, M Miller
Publikováno v:
Scopus-Elsevier
We tested the possibility that lymphocytes and serum obtained directly from a patient with HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP) induce infection in rats. Inbred Fischer F344 immunosuppressed rats were inoculated intrave
Autor:
S. Maayan, A. Achiron, Paul Stark, M. Miller, Walter Bodemer, Matityahu Shaklai, B. Shohat, Horst Hannig, Gerhard Hunsmann
Publikováno v:
Journal of Medical Virology. 56:269-274
A high prevalence of human T-lymphotropic virus type I (HTLV-I) infection among Israeli Jews was previously reported. In the present study, screening for HTLV-I of Israeli Jews was expanded to 10 ethnic groups. HTLV-I antibodies were tested by the pa