Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Matilde Ner"'
Autor:
Olga Cruz-López, Matilde Ner, Francho Nerín-Fonz, Yaiza Jiménez-Martínez, David Araripe, Juan A. Marchal, Houria Boulaiz, Hugo Gutiérrez-de-Terán, Joaquín M. Campos, Ana Conejo-García
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 1551-1561 (2021)
A series of 11 new substituted 1,5-dihydro-4,1-benzoxazepine derivatives was synthesised to study the influence of the methyl group in the 1-(benzenesulphonyl) moiety, the replacement of the purine by the benzotriazole bioisosteric analogue, and the
Externí odkaz:
https://doaj.org/article/bcda5ad136ca41fa807513d29c5746ae
Autor:
Matilde Ner, Juan A. Marchal, Yaiza Jiménez-Martínez, Joaquín M. Campos, Hugo Gutiérrez-de-Terán, Ana Conejo-García, Houria Boulaiz, Francho Nerín-Fonz, David Araripe, Olga Cruz-Lopez
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry
article-version (VoR) Version of Record
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 1551-1561 (2021)
Digibug. Repositorio Institucional de la Universidad de Granada
instname
article-version (VoR) Version of Record
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 1551-1561 (2021)
Digibug. Repositorio Institucional de la Universidad de Granada
instname
A. C. -G. is thankful to Consejeria de Economia, Conocimiento, Empresas y Universidad of the Junta de Andalucia (Excellence Research Project P18-RT-1679) and the Oficina de Transferencia de Resultados de Investigacion of the University of Granada (PR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fa62f8746d461332747e383fb8af54e
http://europepmc.org/articles/PMC8279156
http://europepmc.org/articles/PMC8279156
Autor:
Lisa Mosconi, Matilde Nerattini, Dawn C. Matthews, Steven Jett, Caroline Andy, Schantel Williams, Camila Boneu Yepez, Camila Zarate, Caroline Carlton, Francesca Fauci, Trisha Ajila, Silky Pahlajani, Randolph Andrews, Alberto Pupi, Douglas Ballon, James Kelly, Joseph R. Osborne, Sadek Nehmeh, Matthew Fink, Valentina Berti, Jonathan P. Dyke, Roberta Diaz Brinton
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract 17β-estradiol, the most biologically active estrogen, exerts wide-ranging effects in brain through its action on estrogen receptors (ERs), influencing higher-order cognitive function and neurobiological aging. However, our knowledge of ER e
Externí odkaz:
https://doaj.org/article/04b41408e446414b9a831dd8b790e68f
Autor:
Lisa Mosconi, Schantel Williams, Caroline Carlton, Camila Zarate, Camila Boneu, Francesca Fauci, Trisha Ajila, Matilde Nerattini, Steven Jett, Caroline Andy, Michael Battista, Silky Pahlajani, Joseph Osborne, Roberta Diaz Brinton, Jonathan P. Dyke
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Emerging evidence implicates chronic psychological stress as a risk factor for Alzheimer’s disease (AD). Herein, we examined the relationships between serum cortisol and multimodality brain AD biomarkers in 277 cognitively normal midlife i
Externí odkaz:
https://doaj.org/article/860ade4fa33e4745b368bbe7e2a3c650
Autor:
Caroline Andy, Matilde Nerattini, Steven Jett, Caroline Carlton, Camila Zarate, Camila Boneu, Francesca Fauci, Trisha Ajila, Michael Battista, Silky Pahlajani, Paul Christos, Matthew E. Fink, Schantel Williams, Roberta Diaz Brinton, Lisa Mosconi
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
IntroductionDespite evidence from preclinical studies suggesting estrogen’s neuroprotective effects, the use of menopausal hormone therapy (MHT) to support cognitive function remains controversial.MethodsWe used random-effect meta-analysis and mult
Externí odkaz:
https://doaj.org/article/09c67cec818f437db119942f3f7e5e33
Autor:
Matilde Nerattini, Federica Rubino, Steven Jett, Caroline Andy, Camila Boneu, Camila Zarate, Caroline Carlton, Susan Loeb-Zeitlin, Yelena Havryliuk, Silky Pahlajani, Schantel Williams, Valentina Berti, Paul Christos, Matthew Fink, Jonathan P. Dyke, Roberta Diaz Brinton, Lisa Mosconi
Publikováno v:
Frontiers in Dementia, Vol 2 (2023)
IntroductionIn preclinical studies, menopausal elevations in pituitary gonadotropins, follicle-stimulating hormone (FSH) and luteinizing hormone (LH), trigger Alzheimer's disease (AD) pathology and synaptic loss in female animals. Herein, we took a t
Externí odkaz:
https://doaj.org/article/f884dc760e994d1cb2aac216c5201547
Autor:
Matilde Nerattini, Steven Jett, Caroline Andy, Caroline Carlton, Camila Zarate, Camila Boneu, Michael Battista, Silky Pahlajani, Susan Loeb-Zeitlin, Yelena Havryulik, Schantel Williams, Paul Christos, Matthew Fink, Roberta Diaz Brinton, Lisa Mosconi
Publikováno v:
Frontiers in Aging Neuroscience, Vol 15 (2023)
IntroductionDespite a large preclinical literature demonstrating neuroprotective effects of estrogen, use of menopausal hormone therapy (HT) for Alzheimer’s disease (AD) risk reduction has been controversial. Herein, we conducted a systematic revie
Externí odkaz:
https://doaj.org/article/9e78ef6e633442e78f1abd867fdff785
Autor:
Steven Jett, Camila Boneu, Camila Zarate, Caroline Carlton, Vibha Kodancha, Matilde Nerattini, Michael Battista, Silky Pahlajani, Schantel Williams, Jonathan P. Dyke, Lisa Mosconi
Publikováno v:
Frontiers in Aging Neuroscience, Vol 15 (2023)
Many lines of evidence suggest that mitochondria have a central role in aging-related neurodegenerative diseases, such as Alzheimer's disease (AD). Mitochondrial dysfunction, cerebral energy dysmetabolism and oxidative damage increase with age, and a
Externí odkaz:
https://doaj.org/article/c8e0ba3f8adc4dbbab4e2afb7063b0f7