The gastric mucosa of Atlantic salmon (Salmo salar) is abundant in highly active chitinases

Autor: Matilde Mengkrog Holen, Tina Rise Tuveng, Matthew Peter Kent, Gustav Vaaje‐Kolstad

Publikováno v: FEBS Open Bio, Vol 14, Iss 1, Pp 23-36 (2024)

Atlantic salmon (Salmo salar) possesses a genome containing 10 genes encoding chitinases, yet their functional roles remain poorly understood. In other fish species, chitinases have been primarily linked to digestion, but also to other functions, as

Externí odkaz: https://doaj.org/article/3824161299714a6798113bcd3ebfee08

Comparative regulomics supports pervasive selection on gene dosage following whole genome duplication

Autor: Gareth B. Gillard, Lars Grønvold, Line L. Røsæg, Matilde Mengkrog Holen, Øystein Monsen, Ben F. Koop, Eric B. Rondeau, Manu Kumar Gundappa, John Mendoza, Daniel J. Macqueen, Rori V. Rohlfs, Simen R. Sandve, Torgeir R. Hvidsten

Publikováno v: Genome Biology, Vol 22, Iss 1, Pp 1-18 (2021)

Abstract Background Whole genome duplication (WGD) events have played a major role in eukaryotic genome evolution, but the consequence of these extreme events in adaptive genome evolution is still not well understood. To address this knowledge gap, w

Externí odkaz: https://doaj.org/article/58aca94850bf40708edd64475736db71

The gastric mucosa of Atlantic salmon (Salmo salar) is abundant in highly active chitinases

Autor: Matilde Mengkrog Holen, Tina Rise Tuveng, Matthew Peter Kent, Gustav Vaaje-Kolstad

The Atlantic salmon (Salmo salar) genome contains 10 chitinase encoding genes, but little is known about the function of these chitinases. We show that the protein products of three genes, the family 18 glycoside hydrolase (GH18) chitinases Chia.3, C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c2cb6f2fda6d2f6d2a2644d2daf26f75
https://doi.org/10.1101/2022.05.10.491315

Gene family expansion and functional diversification of chitinase and chitin synthase genes in Atlantic salmon (Salmo salar)

Autor: Matilde Mengkrog Holen, Matthew Peter Kent, Gustav Vaaje-Kolstad, Simen Rød Sandve

BackgroundChitin is one of the most abundant polysaccharides in nature, forming important structures in insects, crustaceans, and fungal cell walls. Vertebrates on the other hand are generally considered “non-chitinous” organisms, despite having

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89b3b3bfa69adb30645cbf165d8ce865
https://doi.org/10.1101/2022.05.05.490710

The structural variation landscape in 492 Atlantic salmon genomes

Autor: Craig R. Primmer, Sigbjørn Lien, Kjetil Hindar, Samuel A.M. Martin, Manu Kumar Gundappa, Matilde Mengkrog Holen, Line Lieblein Røsæg, Ian Johnston, Alicia C. Bertolotti, Ege Pehlivanoglu, Diego Robledo, Harald Sægrov, Teshome Dagne Mulugeta, Daniel J. Macqueen, Torfinn Nome, Simen Rød Sandve, Bjørn Florø-Larsen, Thomas J. Ashton, Matthew Peter Kent, Jaakko Erkinaro, Ryan M. Layer, Louis Bernatchez, Michael Gallagher

Publikováno v: Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Bertolotti, A, Layer, R M, Gundappa, M K, Gallagher, M, Pehlivanoglu, E, Nome, T, Robledo, D, Kent, M P, Røsæg, L L, Holen, M M, Mulugeta, T D, Ashton, T J, Hindar, K, Saegrov, H, Florø-Larsen, B, Erkinaro, J, Primmer, C R, Bernatchez, L, Martin, S A M, Johnston, I A, Sandve, S R, Lien, S & Macqueen, D 2020, ' The structural variation landscape in 492 Atlantic salmon genomes ', Nature Communications, vol. 11, 5176 (2020) . https://doi.org/10.1038/s41467-020-18972-x

Structural variants (SVs) are a major source of genetic and phenotypic variation, but remain challenging to accurately type and are hence poorly characterized in most species. We present an approach for reliable SV discovery in non-model species usin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41225293028e0f134b7dd3ff57c8296e
https://pubmed.ncbi.nlm.nih.gov/33056985