Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Matilde Cañelles"'
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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In December 2019, a novel respiratory coronavirus named SARS-CoV-2 appeared in China, causing the disease termed COVID-19 that has caused millions of infections worldwide. In this article we have analyzed existing evidence on the immune response agai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97075d9c4a1d836da085cce37ad4fb05
http://hdl.handle.net/10261/222705
http://hdl.handle.net/10261/222705
Autor:
Cristina Ruiz-Herguido, M. Carmen Lafita-Navarro, Rocío Aguado, Lucía García-Gutiérrez, Matilde Cañelles, Francisco Martin, Javier León, Eva Garcia-Alegria, Anna Bigas, Kyle Sarnataro
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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Cancer Lett. 2016 May 28;375(1):92-9
UCrea Repositorio Abierto de la Universidad de Cantabria
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Cancer Lett. 2016 May 28;375(1):92-9
UCrea Repositorio Abierto de la Universidad de Cantabria
Chronic myeloid leukemia (CML) progresses from a chronic to a blastic phase, where the leukemic cells are proliferative and undifferentiated. The CML is nowadays successfully treated with BCR-ABL kinase inhibitors as imatinib and its derivatives. NUM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99aafa4733e68b1982edcf56dc7d003e
https://pubmed.ncbi.nlm.nih.gov/26944313
https://pubmed.ncbi.nlm.nih.gov/26944313
Autor:
Chiguang Feng, Kenneth J. Woodside, Elizabeth W. Shores, B. J. Fowlkes, Dalal El-Khoury, Ronald E. Gress, Matilde Cañelles, Jan Lee, Paul E. Love, Barbara A. Vance
Publikováno v:
Scopus-Elsevier
The early activation marker, CD69, is transiently expressed on activated mature T cells and on thymocytes that are undergoing positive or negative selection in the thymus. CD69 is a member of the NK gene complex family of C-type lectin-like signaling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f59bd76474e64e3c47724152968aac27
https://doi.org/10.1093/intimm/dxf020
https://doi.org/10.1093/intimm/dxf020
Autor:
Giulia Franciosa, Saula Checquolo, F. Del Gaudio, N. M. Martin-Blanco, Matilde Cañelles, Isabella Screpanti, L Di Marcotullio, Alberto Gulino, Rocco Palermo
Publikováno v:
Cell Death & Disease
Digital.CSIC. Repositorio Institucional del CSIC
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Digital.CSIC. Repositorio Institucional del CSIC
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Numb asymmetrically segregates at mitosis to control cell fate choices during development. Numb inheritance specifies progenitor over differentiated cell fates, and, paradoxically, also promotes neuronal differentiation, thus indicating that the role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d687739d4f97868a4bf4a4d284e7e4d2
http://hdl.handle.net/10261/130267
http://hdl.handle.net/10261/130267
Autor:
Matilde Cañelles, Nadia Martin-Blanco, Isabella Screpanti, Balbino Alarcón, Gabriel Bretones, Daniel Jiménez Teja, Michael Caraballo, Javier León, Aldo Borroto Revuelta
Publikováno v:
International immunology. 28(3)
Modulation of TCR signaling upon ligand binding is achieved by changes in the equilibrium between TCR degradation, recycling and synthesis; surprisingly, the molecular mechanism of such an important process is not fully understood. Here, we describe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::855c35be46bdee3f8332994489c8d666
https://pubmed.ncbi.nlm.nih.gov/26507128
https://pubmed.ncbi.nlm.nih.gov/26507128
Autor:
Javier León, Pilar Frade, Carlos Richard, Matilde Cañelles, M.Angeles Cuadrado, M. Dolores Delgado, Ana Lerga
Publikováno v:
Biochemical and Biophysical Research Communications. 260:256-264
Treatment of human myeloid leukemia K562 cells with the serine/threonine protein phosphatases inhibitor okadaic acid induced mitotic arrest followed by apoptosis in a synchronized manner. The effect was observed at drug concentrations that inhibited
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6ec0814e62fc66dffb494e9e44bd3c7
https://doi.org/10.1006/bbrc.1999.0852
https://doi.org/10.1006/bbrc.1999.0852
Publikováno v:
Hematology-Science and Practice
Asymmetric division is a process by which stem cells asymmetrically segregate certain proteins, called “cell fate determinants”, in order to generate two functionally different cells. Normally, one of the daughter cells terminally differentiates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9fa9ed8198d49a935ba8b5b61fa8de9
http://www.intechopen.com/articles/show/title/asymmetric-division-in-the-immuno-hematopoietic-system
http://www.intechopen.com/articles/show/title/asymmetric-division-in-the-immuno-hematopoietic-system
Autor:
Matilde Cañelles
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
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2 páginas.
Asymmetric division, a process by which stem cells divide to generate the diversity of cell types that populate adult organisms, has been extensively studied in the last decade. This has led to many exciting discoveries that help us
Asymmetric division, a process by which stem cells divide to generate the diversity of cell types that populate adult organisms, has been extensively studied in the last decade. This has led to many exciting discoveries that help us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa7728d9b0b349861152c046b2df6017
https://doi.org/10.4172/2157-7633.1000e103
https://doi.org/10.4172/2157-7633.1000e103
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
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Stem cells must proliferate and differentiate to generate the lineages that shape mature organs; understanding these 2 processes and their interaction is one of the central themes in current biomedicine. An intriguing aspect is asymmetric division, b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a2780357e9376beac862d95104a7a4d
https://pubmed.ncbi.nlm.nih.gov/20530794
https://pubmed.ncbi.nlm.nih.gov/20530794
Autor:
Ana Lerga, Kathy M Hyland, Carlos Richard, Matilde Cañelles, Chi V. Dang, M. Dolores Delgado, Javier León
Publikováno v:
Oncogene. 14(11)
We have used the human leukemia cell line K562 as a model to study the role of c-myc in differentiation and apoptosis. We have generated stable transfectants of K562 constitutively expressing two c-Myc inhibitory mutants: D106-143, that carries a del
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a52ed97fa8009052544d737168b5d4d5
https://pubmed.ncbi.nlm.nih.gov/9178892
https://pubmed.ncbi.nlm.nih.gov/9178892