Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Matilde, Rusbjerg"'
Publikováno v:
The Journal of organic chemistry. 87(3)
This article discloses the direct α-amination of α-branched aldehydes applying nitrogen-based nucleophiles. Under organocatalyzed, oxidative conditions α-branched aldehydes are umpoled to their electrophilic synthons and, subsequently, displaced b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::85e9b2e9377a313c71b2291037f1bc25
https://pubmed.ncbi.nlm.nih.gov/34610236
https://pubmed.ncbi.nlm.nih.gov/34610236
Autor:
Matilde Rusbjerg, Jakob Blom, Casper L. Barløse, Karl Anker Jørgensen, Henriette N. Tobiesen, Marc V. Iversen, Niels Hammer, Gabriel J. Reyes-Rodríguez, Johannes N. Lamhauge
Publikováno v:
Blom, J, Reyes Rodriguez, G J, Tobiesen, H N, Lamhauge, J N, Iversen, M V, Barløse, C L, Hammer, N, Rusbjerg, M & Jørgensen, K A 2019, ' Umpolung Strategy for α-Functionalization of Aldehydes for the Addition of Thiols and other Nucleophiles ', Angewandte Chemie-International Edition, vol. 58, no. 49, pp. 17856-17862 . https://doi.org/10.1002/anie.201911793
Nucleophile–nucleophile coupling is a challenging transformation in organic chemistry. Herein we present a novel umpolung strategy for α-functionalization of aldehydes with nucleophiles. The strategy uses organocatalytic enamine activation and qui
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6637934f6e9d01618a42daf47b29a1e2
https://pure.au.dk/portal/da/publications/umpolung-strategy-for-functionalization-of-aldehydes-for-the-addition-of-thiols-and-other-nucleophiles(392d5730-182a-4517-8029-cd1380085d7f).html
https://pure.au.dk/portal/da/publications/umpolung-strategy-for-functionalization-of-aldehydes-for-the-addition-of-thiols-and-other-nucleophiles(392d5730-182a-4517-8029-cd1380085d7f).html
