Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Matija, Zelic"'
Autor:
Jerry Wong, Ricard Garcia-Carbonell, Matija Zelic, Samuel B. Ho, Brigid S. Boland, Shih-Jing Yao, Shalin A. Desai, Soumita Das, Núria Planell, Philip A. Harris, Joan Font-Burgada, Koji Taniguchi, John Bertin, Azucena Salas, Manolis Pasparakis, Pete J. Gough, Michelle Kelliher, Michael Karin, Monica Guma
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 9, Iss 2, Pp 295-312 (2020)
Background and Aims: Tumor necrosis factor (TNF) is a major pathogenic effector and a therapeutic target in inflammatory bowel disease (IBD), yet the basis for TNF-induced intestinal epithelial cell (IEC) death is unknown, because TNF does not kill n
Externí odkaz:
https://doaj.org/article/4bf9bd1fe4534fd6a45b7e148464a13a
Autor:
Diana Legarda, Scott J. Justus, Rosalind L. Ang, Nimisha Rikhi, Wenjing Li, Thomas M. Moran, Jianke Zhang, Emiko Mizoguchi, Matija Zelic, Michelle A. Kelliher, J. Magarian Blander, Adrian T. Ting
Publikováno v:
Cell Reports, Vol 15, Iss 11, Pp 2449-2461 (2016)
Tumor necrosis factor (TNF) induces necroptosis, a RIPK3/MLKL-dependent form of inflammatory cell death. In response to infection by Gram-negative bacteria, multiple receptors on macrophages, including TLR4, TNF, and type I IFN receptors, are concurr
Externí odkaz:
https://doaj.org/article/8c0a3848a6e94f09b0ce11ed75eae8fa
Autor:
Sean K. Ryan, Matija Zelic, Yingnan Han, Erin Teeple, Luoman Chen, Mahdiar Sadeghi, Srinivas Shankara, Lilu Guo, Cong Li, Fabrizio Pontarelli, Elizabeth H. Jensen, Ashley L. Comer, Dinesh Kumar, Mindy Zhang, Joseph Gans, Bailin Zhang, Jonathan D. Proto, Jacqueline Saleh, James C. Dodge, Virginia Savova, Deepak Rajpal, Dimitry Ofengeim, Timothy R. Hammond
Publikováno v:
Nature neuroscience.
Iron dysregulation has been implicated in multiple neurodegenerative diseases, including Parkinson’s disease (PD). Iron-loaded microglia are frequently found in affected brain regions, but how iron accumulation influences microglia physiology and c
Autor:
Matija Zelic, Srinivas Shankara, Lilu Guo, Erin Teeple, Jonathan Proto, Deepak K. Rajpal, Joseph Gans, Timothy R. Hammond, Mindy Zhang, Elizabeth H. Jensen, Dimitry Ofengeim, Yingnan Han, Luoman Chen, Dinesh Kumar, Mahdiar Sadeghi, Sean K. Ryan, Cong Li, Fabrizio Pontarelli, Jacqueline Saleh, James C. Dodge, Bailin Zhang
Iron dysregulation has been implicated in multiple neurodegenerative diseases, including Parkinson’s Disease (PD), Amyotrophic Lateral Sclerosis (ALS), and Multiple Sclerosis (MS). One prominent feature of affected brain regions are iron-loaded mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76f8cefbd8e4fabc09cc7277f0f8500b
https://doi.org/10.1101/2021.11.02.466996
https://doi.org/10.1101/2021.11.02.466996
Autor:
Jan Wenzel, Julian U. G. Wagner, Cyril Robil, Peter König, Rolf Hilgenfeld, Beate Lembrich, Christine Stadelmann, Jonas Franz, Denisa Bojkova, Helge Müller-Fielitz, Valentin Sencio, Yun Jiang, François Trottein, Dimitry Ofengeim, Susanne Pfefferle, Kristin Müller, Markus Glatzel, Roberto Villaseñor, Matija Zelic, Markus Krohn, Fabian Ott, Hauke Busch, Frauke Spiecker, Anke Fähnrich, Ludovic Collin, Caio Coelho, Vincent Prevot, Jakob Körbelin, Josephine Lampe, Mariana Shumliakivska, Umit Ozorhan, Stefanie Dimmeler, Klaus Püschel, Jindrich Cinatl, Hermann C. Altmeppen, Rubén Nogueiras, Olaf Jöhren, Florent Sauve, Vanessa Neve, Raphael Schuster, Sonja Binder, Linlin Zhang, Manolis Pasparakis, Markus Schwaninger, Nina Feller, Marietta Zille
Publikováno v:
Nature Neuroscience
Nature Neuroscience, 2021, 24 (11), pp.1522-1533. ⟨10.1038/s41593-021-00926-1⟩
Nature Neuroscience, 2021, 24 (11), pp.1522-1533. ⟨10.1038/s41593-021-00926-1⟩
Coronavirus disease 2019 (COVID-19) can damage cerebral small vessels and cause neurological symptoms. Here we describe structural changes in cerebral small vessels of patients with COVID-19 and elucidate potential mechanisms underlying the vascular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cdd07d7791daed77756622dcdd57625
https://www.hal.inserm.fr/inserm-03741941/document
https://www.hal.inserm.fr/inserm-03741941/document
Autor:
Jan, Wenzel, Josephine, Lampe, Helge, Müller-Fielitz, Raphael, Schuster, Marietta, Zille, Kristin, Müller, Markus, Krohn, Jakob, Körbelin, Linlin, Zhang, Ümit, Özorhan, Vanessa, Neve, Julian U G, Wagner, Denisa, Bojkova, Mariana, Shumliakivska, Yun, Jiang, Anke, Fähnrich, Fabian, Ott, Valentin, Sencio, Cyril, Robil, Susanne, Pfefferle, Florent, Sauve, Caio Fernando Ferreira, Coêlho, Jonas, Franz, Frauke, Spiecker, Beate, Lembrich, Sonja, Binder, Nina, Feller, Peter, König, Hauke, Busch, Ludovic, Collin, Roberto, Villaseñor, Olaf, Jöhren, Hermann C, Altmeppen, Manolis, Pasparakis, Stefanie, Dimmeler, Jindrich, Cinatl, Klaus, Püschel, Matija, Zelic, Dimitry, Ofengeim, Christine, Stadelmann, François, Trottein, Ruben, Nogueiras, Rolf, Hilgenfeld, Markus, Glatzel, Vincent, Prevot, Markus, Schwaninger
Publikováno v:
Nature Neuroscience
Coronavirus disease 2019 (COVID-19) can damage cerebral small vessels and cause neurological symptoms. Here we describe structural changes in cerebral small vessels of patients with COVID-19 and elucidate potential mechanisms underlying the vascular
Autor:
Matija Zelic, Jose Sancho, Yi Li, Nellwyn Hagan, Oleg Butovsky, John L. Kane, Lisa Woodworth, Andrew Scholte, Charlotte Madore, Michael Kothe, Barbara Gisevius, Dimitry Ofengeim, Jacqueline Saleh, Jonathan Proto, Deepak Grover, Maria Fitzgerald, Aiden Haghikia, Jinyu Liu, Amy Mahan
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 11, Iss 10, Pp 1-25 (2020)
Cell Death and Disease, Vol 11, Iss 10, Pp 1-25 (2020)
Microglia serve as the innate immune cells of the central nervous system (CNS) by providing continuous surveillance of the CNS microenvironment and initiating defense mechanisms to protect CNS tissue. Upon injury, microglia transition into an activat
Autor:
Dimitry Ofengeim, Egil Lien, Alexei Degterev, Pontus Orning, Yi Ren, Matija Zelic, Aislinn Keane, Lilu Guo, Lisa Woodworth, Ross C. Gruber, Michael LaMorte, Tai-he Xia, Pequita Loring, Boyao Zhang, Fabrizio Pontarelli, Amy Mahan, Cheng Zhu, Timothy R. Hammond
Publikováno v:
e1-e7
Cell reports
Cell reports
Receptor interacting protein kinase 1 (RIPK1) mediates cell death and inflammatory signaling and is increased in multiple sclerosis (MS) brain samples. Here, we investigate the role of glial RIPK1 kinase activity in mediating MS pathogenesis. We demo
Autor:
P J Gough, Koji Taniguchi, Núria Planell, John Bertin, Soumita Das, Matija Zelic, Manolis Pasparakis, Philip A. Harris, Samuel B. Ho, Ricard Garcia-Carbonell, Shih Jing Yao, Joan Font-Burgada, Michelle A. Kelliher, Azucena Salas, Jerry Wong, Michael Karin, Monica Guma, Shalin A. Desai, Brigid S. Boland
Publikováno v:
Cellular and molecular gastroenterology and hepatology, vol 9, iss 2
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Cellular and Molecular Gastroenterology and Hepatology, Vol 9, Iss 2, Pp 295-312 (2020)
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Cellular and Molecular Gastroenterology and Hepatology, Vol 9, Iss 2, Pp 295-312 (2020)
Background and Aims: Tumor necrosis factor (TNF) is a major pathogenic effector and a therapeutic target in inflammatory bowel disease (IBD), yet the basis for TNF-induced intestinal epithelial cell (IEC) death is unknown, because TNF does not kill n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d066f3e6066a30628cb304b6fb9eaca
https://escholarship.org/uc/item/19s668h3
https://escholarship.org/uc/item/19s668h3
Autor:
Joanne A. O’Donnell, Michelle A. Kelliher, Jesse Lehman, Justine E. Roderick, Katherine A. Fitzgerald, Nicole Hermance, Ann Marshak-Rothstein, Matija Zelic, Stephen Lyle, Manolis Pasparakis, Dalia Martinez-Marin, Ciara G. Doran
Publikováno v:
The Journal of Immunology. 200:737-748
Necroptosis is a form of cell death associated with inflammation; however, the biological consequences of chronic necroptosis are unknown. Necroptosis is mediated by RIPK1, RIPK3, and MLKL kinases but in hematopoietic cells RIPK1 has anti-inflammator