Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Matias I. Autio"'
Autor:
Matias I. Autio, Talal Bin Amin, Arnaud Perrin, Jen Yi Wong, Roger S.-Y. Foo, Shyam Prabhakar
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-17 (2021)
Abstract Background Transposable elements (TE) comprise nearly half of the human genome and their insertions have profound effects to human genetic diversification and as well as disease. Despite their abovementioned significance, there is no consens
Externí odkaz:
https://doaj.org/article/37cbd73da4dc4bac9f79b35ef2968e33
Autor:
C.H. Cole Sims, Matias I. Autio, Adriana Buskin, Christine Cheung, Rakesh Heer, Roger S.Y. Foo, Xin Wang
Publikováno v:
Stem Cell Research, Vol 52, Iss , Pp 102238- (2021)
Two cell lines were generated by CRISPR/Cas9 mediated knockout of MKK7 (MAP2K7) by removal of exon 1 or exons 4 through 7. These knockouts were confirmed at the transcript and protein levels. These hESCs are pluripotent and maintain tri-lineage diffe
Externí odkaz:
https://doaj.org/article/47e52ac9089846f38461d96feb71810b
Autor:
Lay Teng Ang, Antson Kiat Yee Tan, Matias I. Autio, Su Hua Goh, Siew Hua Choo, Kian Leong Lee, Jianmin Tan, Bangfen Pan, Jane Jia Hui Lee, Jen Jen Lum, Christina Ying Yan Lim, Isabelle Kai Xin Yeo, Chloe Jin Yee Wong, Min Liu, Jueween Ling Li Oh, Cheryl Pei Lynn Chia, Chet Hong Loh, Angela Chen, Qingfeng Chen, Irving L. Weissman, Kyle M. Loh, Bing Lim
Publikováno v:
Cell Reports, Vol 22, Iss 8, Pp 2190-2205 (2018)
Summary: How are closely related lineages, including liver, pancreas, and intestines, diversified from a common endodermal origin? Here, we apply principles learned from developmental biology to rapidly reconstitute liver progenitors from human pluri
Externí odkaz:
https://doaj.org/article/18dfda95bb854672b8638aaa6e3a3810
Autor:
Matias I Autio, Efthymios Motakis, Arnaud Perrin, Talal Bin Amin, Zenia Tiang, Dang Vinh Do, Jiaxu Wang, Joanna Tan, Shirley Suet Lee Ding, Wei Xuan Tan, Chang Jie Mick Lee, Adrian Kee Keong Teo, Roger SY Foo
Publikováno v:
eLife, Vol 13 (2024)
Selection of the target site is an inherent question for any project aiming for directed transgene integration. Genomic safe harbour (GSH) loci have been proposed as safe sites in the human genome for transgene integration. Although several sites hav
Externí odkaz:
https://doaj.org/article/6b5c6b6b01aa44959f46ae8b1df90239
Autor:
Roger S.-Y. Foo, Adrian Kee Keong Teo, Wei Xuan Tan, Joanna Tan, Jiaxu Wang, Dang Vinh Do, Zenia Tiang, Talal Bin Amin, Arnaud Perrin, Efthymios Motakis, Matias I. Autio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9561ae42fba0319b729e53f5311bf94
https://doi.org/10.15252/rc.2022981240
https://doi.org/10.15252/rc.2022981240
Autor:
Johann S, Hawe, Rory, Wilson, Katharina T, Schmid, Li, Zhou, Lakshmi Narayanan, Lakshmanan, Benjamin C, Lehne, Brigitte, Kühnel, William R, Scott, Matthias, Wielscher, Yik Weng, Yew, Clemens, Baumbach, Dominic P, Lee, Eirini, Marouli, Manon, Bernard, Liliane, Pfeiffer, Pamela R, Matías-García, Matias I, Autio, Stephane, Bourgeois, Christian, Herder, Ville, Karhunen, Thomas, Meitinger, Holger, Prokisch, Wolfgang, Rathmann, Michael, Roden, Sylvain, Sebert, Jean, Shin, Konstantin, Strauch, Weihua, Zhang, Wilson L W, Tan, Stefanie M, Hauck, Juliane, Merl-Pham, Harald, Grallert, Eudes G V, Barbosa, Thomas, Illig, Annette, Peters, Tomas, Paus, Zdenka, Pausova, Panos, Deloukas, Roger S Y, Foo, Marjo-Riitta, Jarvelin, Jaspal S, Kooner, Marie, Loh, Matthias, Heinig, Christian, Gieger, Melanie, Waldenberger, Krina T, Zondervan
Publikováno v:
Nat. Genet. 54, 18–29 (2022)
We determined the relationships between DNA sequence variation and DNA methylation using blood samples from 3,799 Europeans and 3,195 South Asians. We identify 11,165,559 SNP-CpG associations (methylation quantitative trait loci (meQTL), P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f854cdd047ff8e3bf4d76fef7f78d2a7
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=64018
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=64018
Autor:
Matias I. Autio, Efthymios Motakis, Arnaud Perrin, Talal Bin Amin, Zenia Tiang, Dang Vinh Do, Jiaxu Wang, Joanna Tan, Wei Xuan Tan, Adrian Kee Keong Teo, Roger S.-Y. Foo
SummarySelection of the target site is an inherent question for any project aiming for directed transgene integration. Genomic safe harbour (GSH) loci have been proposed as safe sites in the human genome for transgene integration. Although several si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af2fc56e8d535fb793c5f094f4f1070e
https://doi.org/10.1101/2021.12.07.471422
https://doi.org/10.1101/2021.12.07.471422
Publikováno v:
BMC Genomics
BMC Genomics, Vol 22, Iss 1, Pp 1-17 (2021)
BMC Genomics, Vol 22, Iss 1, Pp 1-17 (2021)
Background Transposable elements (TE) comprise nearly half of the human genome and their insertions have profound effects to human genetic diversification and as well as disease. Despite their abovementioned significance, there is no consensus on the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b88d8677dcce4fac8aa3b3ea058e8c9
https://doi.org/10.1186/s12864-021-08085-0
https://doi.org/10.1186/s12864-021-08085-0
Autor:
Roger Foo, Liyi Cheng, A. Mark Richards, Warren Ky Tan, Matias I. Autio, Vinh Dang Do, Arnaud Perrin, Chester L. Drum, Zenia Tiang, Nikhil Kumar Tulsian, Chrishan J A Ramachandra, Ganesh S. Anand, Zhe Li, Isabelle Bonne, Jianhong Ching, Wilson Lw Tan, Choon Kiat Lim, Derek J. Hausenloy, Mayin Lee
sNicotinamide adenine dinucleotide (NAD) is a critical metabolite and coenzyme for multiple metabolic pathways and cellular processes (1-4). In this study, we identified Singheart, SGHRT as a nuclear genome-encoded NAD+-binding mitochondrial micropep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c566ca11482bcbc8212b3e11f705bf92
https://doi.org/10.1101/2021.10.24.465637
https://doi.org/10.1101/2021.10.24.465637
Autor:
Roger Foo, Cheryl Xueli Chan, Dominic Paul Lee, Xingfan Huang, Chang Jie Mick Lee, Sarah Ng, Melissa J. Fullwood, Motakis Efthymios, Erez Lieberman Aiden, Zenia Tiang, Shyam Prabhakar, Wen Tan Wl, Chukwuemeka George Anene-Nzelu, Matias I. Autio, Tuan Danh Anh Luu, Jianming Jiang, Peter Yiqing Li
Publikováno v:
Circulation. 139:1937-1956
Background: The human genome folds in 3 dimensions to form thousands of chromatin loops inside the nucleus, encasing genes and cis -regulatory elements for accurate gene expression control. Physical tethers of loops are anchored by the DNA-binding pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd9b377ba72a72254defb17e63f92cbc
https://doi.org/10.1161/circulationaha.118.036726
https://doi.org/10.1161/circulationaha.118.036726