Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Mati Nemera"'
Oncogenic signaling inhibits c-FLIPL expression and its non-apoptotic function during ECM-detachment
Autor:
Matyas Abel Tsegaye, Jianping He, Kyle McGeehan, Ireland M. Murphy, Mati Nemera, Zachary T. Schafer
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Inhibition of programmed cell death pathways is frequently observed in cancer cells where it functions to facilitate tumor progression. However, some proteins involved in the regulation of cell death function dichotomously to both promote an
Externí odkaz:
https://doaj.org/article/d62654ece9dd4e54ab38c4da97e1c7b1
Autor:
Naveen C. Reddy, Shahriyar P. Majidi, Lingchun Kong, Mati Nemera, Cole J. Ferguson, Michael Moore, Tassia M. Goncalves, Hai-Kun Liu, James A. J. Fitzpatrick, Guoyan Zhao, Tomoko Yamada, Azad Bonni, Harrison W. Gabel
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
CHARGE syndrome that affects cerebellar development can be caused by haploinsufficiency of the chromatin remodeling enzyme CHD7; however the precise role of CHD7 remains unknown. Here the authors show CHD7 promotes chromatin accessibility and enhance
Externí odkaz:
https://doaj.org/article/6b65df7f5b89436183b44caa5fad1079
Autor:
Hai-Kun Liu, Michael P. Moore, Tassia Mangetti Gonçalves, Naveen C. Reddy, James A. J. Fitzpatrick, Azad Bonni, Cole J. Ferguson, Mati Nemera, Harrison W. Gabel, Shahriyar P. Majidi, Lingchun Kong, Tomoko Yamada, Guoyan Zhao
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Nature Communications
Nature Communications
Regulation of chromatin plays fundamental roles in the development of the brain. Haploinsufficiency of the chromatin remodeling enzyme CHD7 causes CHARGE syndrome, a genetic disorder that affects the development of the cerebellum. However, how CHD7 c
Oncogenic signaling inhibits c-FLIPL expression and its non-apoptotic function during ECM-detachment
Autor:
Ireland M Murphy, Mati Nemera, Zachary T. Schafer, Jianping He, Kyle McGeehan, Matyas Abel Tsegaye
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Inhibition of programmed cell death pathways is frequently observed in cancer cells where it functions to facilitate tumor progression. However, some proteins involved in the regulation of cell death function dichotomously to both promote and inhibit
Inhibition of programmed cell death pathways is frequently observed in cancer cells where it functions to facilitate tumor progression. However, some proteins involved in the regulation of cell death function dichotomously to both promote and inhibit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e24ba50c16b136b270c56d0fad434098
https://doi.org/10.1101/2021.04.19.440544
https://doi.org/10.1101/2021.04.19.440544
Publikováno v:
Cancer Research. 81:1980-1980
The metastasis of cancer cells to distant sites accounts for over 90% of cancer related deaths. In order to metastasize, cancer cells must be able to survive during extracellular matrix (ECM) detachment, namely by blocking anoikis (a caspase-dependen
Publikováno v:
Cancer Research. 80:1444-1444
The metastasis of cancer cells to distant sites accounts for over 90% of cancer related deaths. In order to metastasize, cancer cells must be able to survive during extracellular matrix (ECM) detachment, namely by blocking anoikis – caspase depende
Publikováno v:
Cancer Research. 78:316-316
The tumor microenvironment (TME), comprised of a heterogeneous population of transformed and non-transformed cells, plays a crucial role in cancer growth. Studies have shown that there is continuous bidirectional communication between cancer cells an