Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Mati Mann"'
Autor:
Mati Mann, Arnav Mehta, Jimmy L. Zhao, Kevin Lee, Georgi K. Marinov, Yvette Garcia-Flores, Li-Fan Lu, Alexander Y. Rudensky, David Baltimore
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
MicroRNAs (miR) are important regulators of gene transcription, with miR-155 and miR-146a both implicated in macrophage activation. Here the authors show that NF-κB signalling, miR-155 and miR-146a form a complex network of cross-regulations to cont
Externí odkaz:
https://doaj.org/article/4ae78de76bc742c580b294dc0c5d59fe
Autor:
Mati Mann, Arnav Mehta, Carl G. de Boer, Monika S. Kowalczyk, Kevin Lee, Pearce Haldeman, Noga Rogel, Abigail R. Knecht, Daneyal Farouq, Aviv Regev, David Baltimore
Publikováno v:
Cell Reports, Vol 25, Iss 11, Pp 2992-3005.e5 (2018)
Summary: Long-term hematopoietic stem cells (LT-HSCs) maintain hematopoietic output throughout an animal’s lifespan. However, with age, the balance is disrupted, and LT-HSCs produce a myeloid-biased output, resulting in poor immune responses to inf
Externí odkaz:
https://doaj.org/article/85898a85ed134dbda596eeb59b1ecbda
Autor:
Mati Mann, Arnav Mehta, Jimmy L. Zhao, Kevin Lee, Georgi K. Marinov, Yvette Garcia-Flores, Li-Fan Lu, Alexander Y. Rudensky, David Baltimore
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
Li-Fan Lu and Alexander Y. Rudensky, who supplied miR-146a floxed mice used in this study, were inadvertently omitted from the author list in the originally published version of this Article. This has now been corrected in both the PDF and HTML versi
Externí odkaz:
https://doaj.org/article/6c054721a1f749df9dd8055593e5815d
Publikováno v:
RNA
At the heart of an innate immune response lies a tightly regulated gene expression program. This precise regulation is crucial because small changes can shift the balance from protective to destructive immunity. Here we identify a frequently used alt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3d700015130e03cb32486a242f3bb33
https://resolver.caltech.edu/CaltechAUTHORS:20191125-134707503
https://resolver.caltech.edu/CaltechAUTHORS:20191125-134707503
Autor:
Xiuli Wang, Zhuoran Zhang, Mark Boldin, Ching Ouyang, Yu-Lin Su, Guido Marcucci, Bin Zhang, Stephen J. Forman, David Baltimore, Dayson Moreira, Mati Mann, Ling Li, Dongfang Wang, Marcin Kortylewski, Tomasz Adamus, Piotr Swiderski, Xin He
NF-κB is a key regulator of inflammation and cancer progression, with an important role in leukemogenesis. Despite its therapeutic potential, targeting NF-κB using pharmacologic inhibitors has proven challenging. Here, we describe a myeloid cell–
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb141c1901c2c5318bfb01dfbf216692
https://resolver.caltech.edu/CaltechAUTHORS:20191218-082734179
https://resolver.caltech.edu/CaltechAUTHORS:20191218-082734179
Autor:
Yvette Garcia-Flores, Arnav Mehta, Kevin Y. Lee, David Baltimore, Jimmy L. Zhao, Li-Fan Lu, Mati Mann, Georgi K. Marinov, Alexander Y. Rudensky
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Nature Communications
BASE-Bielefeld Academic Search Engine
Nature Communications
BASE-Bielefeld Academic Search Engine
The innate inflammatory response must be tightly regulated to ensure effective immune protection. NF-κB is a key mediator of the inflammatory response, and its dysregulation has been associated with immune-related malignancies. Here, we describe a m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96ac01f0a5f0a71551b65986641893ff
https://doaj.org/article/4ae78de76bc742c580b294dc0c5d59fe
https://doaj.org/article/4ae78de76bc742c580b294dc0c5d59fe
Autor:
Alexander Y. Rudensky, Arnav Mehta, Kevin Y. Lee, Yvette Garcia-Flores, Jimmy L. Zhao, David Baltimore, Mati Mann, Georgi K. Marinov, Li-Fan Lu
Publikováno v:
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
The innate inflammatory response must be tightly regulated to ensure effective immune protection. NF-κB is a key mediator of the inflammatory response, and its dysregulation has been associated with immune-related malignancies. Here, we describe a m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b1d0f7828cff50e95648cde29629062
http://europepmc.org/articles/PMC6095848
http://europepmc.org/articles/PMC6095848
Autor:
Arnav Mehta, Georgi K. Marinov, Yvette Garcia-Flores, David Baltimore, Devdoot Majumdar, Kamal Chowdhury, Erdem Erikci, Mati Mann, Xiaomi Du, Jimmy L. Zhao
Publikováno v:
The Journal of Experimental Medicine
Journal of Experimental Medicine
Journal of Experimental Medicine
Mehta et al. uncover a novel role for miR-212/132 as a regulator of early B cell development.
MicroRNAs have emerged as key regulators of B cell fate decisions and immune function. Deregulation of several microRNAs in B cells leads to the develo
MicroRNAs have emerged as key regulators of B cell fate decisions and immune function. Deregulation of several microRNAs in B cells leads to the develo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20ded41324f5ec3472cd898093b5bd54
http://europepmc.org/articles/PMC4577845
http://europepmc.org/articles/PMC4577845
Autor:
Mati Mann, Arnav Mehta, Carl de Boer, Monika S. Kowalczyk, Kevin Lee, Noga Rogel, Abigail R. Knecht, Daneyal Farouq, Aviv Regev, David Baltimore
Long-term hematopoietic stem cells (LT-HSCs) maintain hematopoietic output throughout an animal's lifespan. With age, however, they produce a myeloid-biased output that may lead to poor immune responses to infectious challenge and the development of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e74a41fd5e11495d7159b650fc446967
https://doi.org/10.1101/163402
https://doi.org/10.1101/163402
Autor:
Kevin Y. Lee, Arnav Mehta, Daneyal Farouq, Noga Rogel, David Baltimore, Abigail Knecht, Carl G. de Boer, Mati Mann, Monika S. Kowalczyk, Pearce Haldeman, Aviv Regev
Publikováno v:
Cell Reports, Vol 25, Iss 11, Pp 2992-3005.e5 (2018)
Summary: Long-term hematopoietic stem cells (LT-HSCs) maintain hematopoietic output throughout an animal’s lifespan. However, with age, the balance is disrupted, and LT-HSCs produce a myeloid-biased output, resulting in poor immune responses to inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a110090db8ca0441d2956cac24657d6
https://doi.org/10.1016/j.celrep.2018.11.056
https://doi.org/10.1016/j.celrep.2018.11.056