Zobrazeno 1 - 10
of 367
pro vyhledávání: '"Mati, Fridkin"'
Autor:
Michal Eger, Tamar Liron, Sahar Hiram-Bab, Zamzam Awida, Eliezer Giladi, David Dangoor, Mati Fridkin, David Kohavi, Illana Gozes, Yankel Gabet
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
The common use of dental and orthopedic implants calls for special attention to the immune response leading to peri-prosthetic bone loss and implant failure. In addition to the well-established microbial etiology for oral implant failure, wear debris
Externí odkaz:
https://doaj.org/article/113e06734ff14bf49053936ef612424a
Publikováno v:
Pharmaceutics, Vol 14, Iss 1, p 71 (2021)
A family of monomodified bovine serum albumin (BSA) linked to methotrexate (MTX) through a variety of spacers was prepared. All analogues were found to be prodrugs having low MTX-inhibitory potencies toward dihydrofolate reductase in a cell-free syst
Externí odkaz:
https://doaj.org/article/2bb39ed04d5d425fa5ed342d4d5f4f28
Autor:
Itzik Cooper, Orly Ravid, Daniel Rand, Dana Atrakchi, Chen Shemesh, Yael Bresler, Gili Ben-Nissan, Michal Sharon, Mati Fridkin, Yoram Shechter
Publikováno v:
Pharmaceutics, Vol 13, Iss 10, p 1557 (2021)
Human serum albumin (HSA) is efficiently taken up by cancer cells as a source of carbon and energy. In this study, we prepared a monomodified derivative of HSA covalently linked to an EDTA derivative and investigated its efficacy to shuttle weakly an
Externí odkaz:
https://doaj.org/article/4f960feba0fb4d50b065ec936642eb19
Autor:
Hadar Neuman, Hadar Mor, Tomer Bashi, Or Givol, Abdulla Watad, Asaf Shemer, Alexander Volkov, Iris Barshack, Mati Fridkin, Miri Blank, Yehuda Shoenfeld, Omry Koren
Publikováno v:
mSystems, Vol 4, Iss 1 (2019)
ABSTRACT The hygiene hypothesis claims that the lack of exposure to microorganisms in developed countries correlates with a rise in the incidence of autoimmune diseases. It was also found that helminths are able to modulate the immune response in hos
Externí odkaz:
https://doaj.org/article/a494198b60ab4dbba814dd45571a8adb
Autor:
Miri Blank, Tomer Bashi, Jordan Lachnish, Dana Ben-Ami-Shor, Ora Shovman, Mati Fridkin, Miriam Eisenstein, Alexander Volkov, Iris Barshack, Yehuda Shoenfeld
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0200615 (2018)
A novel small molecule named tuftsin-phosphorylcholine (TPC), which is linked to the biological activity of helminths, was constructed. The current study address the effect of TPC treatment in established collagen-induced arthritis (CIA) mice and pro
Externí odkaz:
https://doaj.org/article/7a19a0fe7c024416ba4775feeb1784bc
Autor:
Hila Ben-Amram, Tomer Bashi, Nir Werbner, Hadar Neuman, Mati Fridkin, Miri Blank, Yehuda Shoenfeld, Omry Koren
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
Rheumatoid arthritis (RA) is characterized by chronic autoinflammation of the joints, with a prevalence of about 1% in Western populations. Evidence in recent years has linked RA to changes in the gut microbiota (dysbiosis). Interestingly, helminths
Externí odkaz:
https://doaj.org/article/89eadc9b9adc4289bbff132ed53e7650
Publikováno v:
Pharmaceuticals, Vol 7, Iss 2, Pp 113-135 (2014)
Brain network dysfunction in Alzheimer’s disease (AD) involves many proteins (enzymes), processes and pathways, which overlap and influence one another in AD pathogenesis. This complexity challenges the dominant paradigm in drug discovery or a sing
Externí odkaz:
https://doaj.org/article/9f25f9f491a04d579b5437aee459699f
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0158352 (2016)
In this study, we examined the possibility of introducing methotrexate (MTX) to the carboxylate rather than to the ε-amino side chains of proteins. We found that MTX-amino compounds covalently linked to the carboxylate moieties of macromolecules, un
Externí odkaz:
https://doaj.org/article/f850cb7c35c3403494eed9007f2ef101
Publikováno v:
NeuroPsychopharmacotherapy ISBN: 9783030620585
NeuroPsychopharmacotherapy ISBN: 9783319560151
NeuroPsychopharmacotherapy ISBN: 9783319560151
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fcccf57197ad6a018a36f366218228b
https://doi.org/10.1007/978-3-030-62059-2_234
https://doi.org/10.1007/978-3-030-62059-2_234
Autor:
Michal Sharon, Orly Ravid, Gili Ben-Nissan, Yoram Shechter, Daniel Rand, Itzik Cooper, Dana Atrakchi, Yael Bresler, Mati Fridkin, Chen Shemesh
Publikováno v:
Pharmaceutics
Volume 13
Issue 10
Pharmaceutics, Vol 13, Iss 1557, p 1557 (2021)
Volume 13
Issue 10
Pharmaceutics, Vol 13, Iss 1557, p 1557 (2021)
Human serum albumin (HSA) is efficiently taken up by cancer cells as a source of carbon and energy. In this study, we prepared a monomodified derivative of HSA covalently linked to an EDTA derivative and investigated its efficacy to shuttle weakly an