Výsledky vyhledávání - "Mathumathi Rajavel"

Akademický článek

Exception to the Rule: Genomic Characterization of Naturally Occurring Unusual Vibrio cholerae Strains with a Single Chromosome

Autor: Gary Xie, Shannon L. Johnson, Karen W. Davenport, Mathumathi Rajavel, Torsten Waldminghaus, John C. Detter, Patrick S. Chain, Shanmuga Sozhamannan

Publikováno v: International Journal of Genomics, Vol 2017 (2017)

The genetic make-up of most bacteria is encoded in a single chromosome while about 10% have more than one chromosome. Among these, Vibrio cholerae, with two chromosomes, has served as a model system to study various aspects of chromosome maintenance,

Externí odkaz: https://doaj.org/article/cf6c831c14ab4229a036ba19a93586a2

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Conversion of a Cosubstrate to an Inhibitor: Phosphorylation Mutants of Nicotinic Acid Phosphoribosyltransferase

Autor: Dominique Lalo, Jeffrey W. Gross, Charles Grubmeyer, Mathumathi Rajavel

Publikováno v: Biochemistry. 37:4181-4188

Nicotinic acid phosphoribosyltransferase (NAPRTase; EC 2.4.2.11) forms nicotinic acid mononucleotide (NAMN) and PPi from 5-phosphoribosyl 1-pyrophosphate (PRPP) and nicotinic acid (NA). The Vmax NAMN synthesis activity of the Salmonella typhimurium e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73cad9f34860939dcc4d7f91ae91aa9a
https://doi.org/10.1021/bi9720134

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Whole genome sequencing and comparative genomic analyses of two Vibrio cholerae O139 Bengal-specific Podoviruses to other N4-like phages reveal extensive genetic diversity

Autor: Derrick E, Fouts, Jochen, Klumpp, Kimberly A, Bishop-Lilly, Mathumathi, Rajavel, Kristin M, Willner, Amy, Butani, Matthew, Henry, Biswajit, Biswas, Manrong, Li, M John, Albert, Martin J, Loessner, Richard, Calendar, Shanmuga, Sozhamannan

Publikováno v: Virology Journal

Background Vibrio cholerae O139 Bengal is the only serogroup other than O1 implicated in cholera epidemics. We describe the isolation and characterization of an O139 serogroup-specific phage, vB_VchP_VchO139-I (ϕVchO139-I) that has similar host rang

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::67f6665d2b92418897a443c0516aed61
https://pubmed.ncbi.nlm.nih.gov/23714204

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Limited Proteolysis of Salmonella typhimurium Nicotinic Acid Phosphoribosyltransferase Reveals ATP-Linked Conformational Change

Autor: Mathumathi Rajavel, Edy Segura, Jeffrey W. Gross, Charles Grubmeyer, William T. Moore

Publikováno v: Biochemistry. 35:3909-3916

Nicotinic acid phosphoribosyltransferase (NAPRTase;EC 2.4.2.11) couples stoichiometric ATP hydrolysis with formation of nicotinate mononucleotide (NAMN) from nicotinic acid and alpha-D-5-phosphoribosyl 1-pyrophosphate (PRPP). Trypsin rapidly inactiva

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebea0ef2f3e0f22e7848d0b986d2f904
https://doi.org/10.1021/bi951791y

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Whole-Genome Sequencing (WGS) and the Changing Landscape of Bacterial Genetics

Autor: Kimberly A. Bishop-Lilly, Mathumathi Rajavel

Publikováno v: Microbe Magazine. 5:41-42

Shotgun sequencing of Haemophilus influenzae in 1995 is traditionally considered to be the dawn of the modern era of whole genome sequencing (WGS). In 2004, the introduction of pyrosequencing based (454/Roche) massively parallel sequencing (MPS) brou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ce8db89254f2be27c896afb225ab3010
https://doi.org/10.1128/microbe.5.41.3

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Mid2 Is a Putative Sensor for Cell Integrity Signaling in Saccharomyces cerevisiae

Autor: Mathumathi Rajavel, Benjamin M. Buehrer, David E. Levin, Bevin Philip, Beverly Errede

Hcs77 is a putative cell surface sensor for cell integrity signaling in Saccharomyces cerevisiae. Its loss of function results in cell lysis during growth at elevated temperatures (e.g., 39 degrees C) and impaired signaling to the Mpk1 mitogen-activa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ccf48b6a9bd4e2b31b4a9b70d317030
https://europepmc.org/articles/PMC104356/

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[2] Energy coupling through molecular discrimination: Nicotinate phosphoribosyltransferase

Autor: Jeffrey W. Gross, Charles Grubmeyer, Mathumathi Rajavel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ab994ae4a05534317bbe35d36858dd16
https://doi.org/10.1016/s0076-6879(99)08004-0

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Kinetic mechanism of nicotinic acid phosphoribosyltransferase: implications for energy coupling

Autor: Charles Grubmeyer, Jeffrey W. Gross, Mathumathi Rajavel

Publikováno v: Biochemistry. 37(12)

Nicotinic acid phosphoribosyltransferase (NAPRTase; EC 2.4.2.11) is a facultative ATPase that uses the energy of ATP hydrolysis to drive the synthesis of nicotinate mononucleotide and pyrophosphate from nicotinic acid (NA) and phosphoribosyl pyrophos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bc6d883b6d37e6d248dd5c060d048be
https://pubmed.ncbi.nlm.nih.gov/9521741

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Energy coupling in Salmonella typhimurium nicotinic acid phosphoribosyltransferase: identification of His-219 as site of phosphorylation

Autor: Jeffrey W. Gross, Charles Grubmeyer, Edy Segura, Mathumathi Rajavel

Publikováno v: Biochemistry. 35(13)

Energy coupling between ATP hydrolysis and other enzyme reactions requires the phosphorylation of substrate-derived intermediates, or the existence of enzyme-derived intermediates capable of storage and transfer of energy. Salmonella typhimurium nico

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3153eefd6e4f2476549ff03b99ce5567
https://pubmed.ncbi.nlm.nih.gov/8672422

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