Blooming of Unusual Cytochrome P450s by Tandem Duplication in the Pathogenic Fungus Conidiobolus coronatus

Autor: Mathula Lancelot Ngwenya, A. K. Basson, Jae-Hyuk Yu, David R. Nelson, Wanping Chen, Khajamohiddin Syed, Jabulani Siyabonga Shandu

Publikováno v: International Journal of Molecular Sciences
Volume 19
Issue 6
International Journal of Molecular Sciences, Vol 19, Iss 6, p 1711 (2018)

While the Zygomycete fungus Conidiobolus coronatus primarily infects insects, it can be pathogenic to mammals as well, including humans. High variability in the treatment of this fungal infection with currently available drugs, including azole drugs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b5b8505c4c077785d4bbb12f36cfe36

Comparative Analyses of Cytochrome P450s and Those Associated with Secondary Metabolism in Bacillus Species

Autor: Jae-Hyuk Yu, Abidemi Paul Kappo, Wanping Chen, Khajamohiddin Syed, Mathula Lancelot Ngwenya, David R. Nelson, Bongumusa Comfort Mthethwa, Rajshekhar Karpoormath, Puleng Rosinah Syed

Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 19, Iss 11, p 3623 (2018)
Volume 19
Issue 11

Cytochrome P450 monooxygenases (CYPs/P450s) are among the most catalytically-diverse enzymes, capable of performing enzymatic reactions with chemo-, regio-, and stereo-selectivity. Our understanding of P450s&rsquo
role in secondary metabolite bi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4852f747bb2c15cc8d14c8bedbb9ddd
https://doi.org/10.3390/ijms19113623