Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Mathilde Pantin"'
Autor:
Fabien Boeda, Laurent Fontaine, Mathilde Pantin, Philippe Bertus, M. S. M. Pearson-Long, Julien Caillé
Publikováno v:
European Journal of Organic Chemistry. 2019:7359-7366
Autor:
Hyunkyung Yu, Nathalie Bellocq, Youngeun Ha, Hyunuk Kim, Yunyeon Kim, Bu-Nam Jeon, Léo Marx, Mathilde Pantin, Hyunjin Yoo, Seungmin Byun, Joo-Yeon Chung, Mi Young Cha, Patrick Garrouste, Frédéric Lévy
Publikováno v:
Cancer Research. 82:1760-1760
Antibody-drug conjugates (ADCs) are considered as promising cancer treatment modalities that combine the selectivity of antibodies and the cytotoxic properties of payloads using chemical linkers. However, despite their success, ADCs still suffer from
Autor:
Noemie Luong, Nathalie Bellocq, Leo Marx, Mathilde Pantin, Benjamin Tchumi, Marie-Claude Roubaudi-Fraschini, Camille Riff, Manfred Mutter, Antoine Attinger
Publikováno v:
Cancer Research. 82:1762-1762
Antibody drug conjugates (ADCs) represent an attractive approach to bring very cytotoxic drugs into tumors while avoiding systemic toxicities. Currently, most commercially available ADCs come with toxicities associated with the nonspecific release of
Publikováno v:
The Journal of Organic Chemistry. 82:11225-11229
The stereoselective access to stereotriads as important polyketide building blocks is reported on the basis of the Krische-type hydrogen-mediated syn-crotylation. The products were obtained with an extremely high diastereoselectivity (dr >99:1), and
Autor:
Fabien Boeda, Jordan Saillour, Mathilde Pantin, M. S. M. Pearson-Long, Philippe Bertus, Florent Bodinier, Yassine M. Youssouf
Publikováno v:
Tetrahedron
Tetrahedron, Elsevier, 2019, 75 (33), pp.4657-4662. ⟨10.1016/j.tet.2019.07.010⟩
Tetrahedron, Elsevier, 2019, 75 (33), pp.4657-4662. ⟨10.1016/j.tet.2019.07.010⟩
International audience; A convenient access to 2-hydroxycyclopentenones was designed from acylcyanohydrins, byusing titanacyclopropane complexes as nucleophilic partners and an intramolecular aldolcondensation in basic conditions. The development of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6fa4508ef034ba57e7b1892370478bb
https://hal.archives-ouvertes.fr/hal-02312591/document
https://hal.archives-ouvertes.fr/hal-02312591/document
Publikováno v:
SYNTHESIS
SYNTHESIS, Georg Thieme Verlag, 2019, 51 (06), pp.1329-1341. ⟨10.1055/s-0037-1611704⟩
SYNTHESIS, Georg Thieme Verlag, 2019, 51 (06), pp.1329-1341. ⟨10.1055/s-0037-1611704⟩
International audience; Allylzinc reagents were used to access highly functionalized tertiary carbinamine derivatives in high yields from cyanoesters and cyanocarbonates. While the monoaddition of organometallics on nitriles is generally observed, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea06229ccf55110bad0c483e69ea45a5
https://hal.archives-ouvertes.fr/hal-02132643
https://hal.archives-ouvertes.fr/hal-02132643
Publikováno v:
The Journal of organic chemistry. 83(13)
The asymmetric total synthesis of the polyketide benzannulated spiroketal natural product, (−)-peniphenone A, is reported. The key reaction in the synthesis involved sp3–sp2 Negishi cross-coupling between a chiral organozinc species and an aryl b
Autor:
Benjamin Breitenbach, Daniel P. Furkert, Ina Sroka, Mathilde Pantin, Margaret A. Brimble, Ludovic Juen
Publikováno v:
European Journal of Organic Chemistry. 2014:7806-7809
A family of nonsymmetrical Mitsunobu reagents possessing both dialkyl amide and ester substituents was developed. These new reagents were readily prepared in a single pot from inexpensive, commercially available materials by using a scalable and envi
Autor:
François Carreaux, Aymeric Siard, Sylvain Collet, Monique Mathé-Allainmat, André Guingant, Jacques Lebreton, Gilles Dujardin, Thibaud Mabit, Laura Foulgoc, Drissa Sissouma, Mathilde Pantin, Doumadé Zon
Publikováno v:
Journal of Organic Chemistry
Journal of Organic Chemistry, American Chemical Society, 2017, 82 (11), pp.5710-5719. ⟨10.1021/acs.joc.7b00544⟩
Journal of Organic Chemistry, 2017, 82 (11), pp.5710-5719. ⟨10.1021/acs.joc.7b00544⟩
Journal of Organic Chemistry, American Chemical Society, 2017, 82 (11), pp.5710-5719. ⟨10.1021/acs.joc.7b00544⟩
Journal of Organic Chemistry, 2017, 82 (11), pp.5710-5719. ⟨10.1021/acs.joc.7b00544⟩
International audience; An efficient access for the synthesis of pluramycinones is described. Total syntheses of racemic γ-indomycinone and kidamycinone were achieved by means of two Diels-Alder reactions. A first Diels-Alder condensation followed b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b759446bc013ba5a13dd0f8da396a98d
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01533331/document
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01533331/document
Autor:
Laura Foulgoc, André Guingant, Doumadé Zon, Romy Vomiandry, Drissa Sissouma, Mathilde Pantin, Sylvain Collet
Publikováno v:
Tetrahedron Letters. 56:2110-2112
The total synthesis of racemic γ-indomycinone has been achieved following an innovating convergent approach. The key step in the construction of the tetracyclic core corresponds to a Diels–Alder reaction between a substituted 5-isoprenyl-3,4-dihyd