Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Mathilde Löbsch"'
Autor:
Thomas Wanek, Severin Mairinger, Thomas Filip, Mathilde Löbsch, Johann Stanek, Claudia Kuntner
Publikováno v:
Frontiers in Physics, Vol 11 (2023)
Introduction: Current small-animal PET instrumentation provides sufficient resolution, sensitivity, and quantitative accurate information on the radiotracer distribution within the whole body. However, most preclinical imaging studies focus on the di
Externí odkaz:
https://doaj.org/article/3aca3392b93647d2b3823879d839eada
Autor:
Irene Hernández-Lozano, Severin Mairinger, Thomas Filip, Mathilde Löbsch, Johann Stanek, Claudia Kuntner, Martin Bauer, Markus Zeitlinger, Marcus Hacker, Thomas H. Helbich, Thomas Wanek, Oliver Langer
Publikováno v:
Antimicrobial Agents and Chemotherapy.
Transporter-mediated drug-drug interactions (DDIs) are of concern in antimicrobial drug development, as they can have serious safety consequences. We used positron emission tomography (PET) imaging-based pharmacokinetic (PK) analysis to assess the ef
Autor:
Michael Wölfl-Duchek, Severin Mairinger, Irene Hernández-Lozano, Thomas Filip, Viktoria Zoufal, Mathilde Löbsch, Johann Stanek, Claudia Kuntner, Thomas Wanek, Martin Bauer, Jens Pahnke, Oliver Langer
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 12; Pages: 6514
Multidrug resistance-associated protein 1 (MRP1, encoded by the ABCC1 gene) may contribute to the clearance of amyloid-beta (Aβ) peptides from the brain into the blood and stimulation of MRP1 transport activity may be a therapeutic approach to enhan
Autor:
Severin Mairinger, Irene Hernández-Lozano, Lena Zachhuber, Thomas Filip, Mathilde Löbsch, Markus Zeitlinger, Marcus Hacker, Carsten Ehrhardt, Oliver Langer
Publikováno v:
European Journal of Pharmaceutical Sciences. 184:106414
Autor:
Severin Mairinger, Irene Hernández-Lozano, Thomas Filip, Mathilde Löbsch, Johann Stanek, Markus Zeitlinger, Marcus Hacker, Nicolas Tournier, Thomas Wanek, Carsten Ehrhardt, Oliver Langer
Publikováno v:
European Journal of Pharmaceutical Sciences. 183:106404
Autor:
Severin Mairinger, Irene Hernández-Lozano, Thomas Filip, Michael Sauberer, Mathilde Löbsch, Johann Stanek, Thomas Wanek, Johannes A. Sake, Thomas Pekar, Carsten Ehrhardt, Oliver Langer
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 349
P-glycoprotein (P-gp) and breast cancer resistance protein (BCRP) are two efflux transporters which are expressed in the apical (i.e. airway lumen-facing) membranes of lung epithelial cells. To assess the influence of P-gp and BCRP on the pulmonary d