Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Mathilda T.M. Mommersteeg"'
Autor:
William T. Stockdale, Madeleine E. Lemieux, Abigail C. Killen, Juanjuan Zhao, Zhilian Hu, Joey Riepsaame, Noémie Hamilton, Tetsuhiro Kudoh, Paul R. Riley, Ronny van Aerle, Yoshiyuki Yamamoto, Mathilda T.M. Mommersteeg
Publikováno v:
Cell Reports, Vol 25, Iss 8, Pp 1997-2007.e7 (2018)
Summary: Although Astyanax mexicanus surface fish regenerate their hearts after injury, their Pachón cave-dwelling counterparts cannot and, instead, form a permanent fibrotic scar, similar to the human heart. Myocardial proliferation peaks at simila
Externí odkaz:
https://doaj.org/article/50b4dde1883046998c94a2044fce2a44
Autor:
Ingeborg B. Hooijkaas, Gerard J.J. Boink, Phil Barnett, Vincent Wakker, Jan Hendrik van Weerd, Mathilda T.M. Mommersteeg, Karel van Duijvenboden, Rajiv A Mohan, Jeroen Bakkers, Jianan Wang, Fernanda M Bosada, Bas J. Boukens, Ruben Coronel, Corrie de Gier-de Vries, Vincent M. Christoffels
Publikováno v:
Proceedings of the National Academy of Sciences
Proceedings of the National Academy of Sciences of the United States of America, 117(31), 18617-18626. National Academy of Sciences
Proc Natl Acad Sci U S A
Proceedings of the National Academy of Sciences of the United States of America, 117(31), 18617-18626. National Academy of Sciences
Proc Natl Acad Sci U S A
Genome-wide association studies have identified noncoding variants near TBX3 that are associated with PR interval and QRS duration, suggesting that subtle changes in TBX3 expression affect atrioventricular conduction system function. To explore wheth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8663cd23b81fb29e373e075da220d7c
https://doi.org/10.1073/pnas.1919379117
https://doi.org/10.1073/pnas.1919379117
Autor:
Rachel L. Moran, Estephany Ferrufino, Alexander Kenzior, Madeleine E. Lemieux, Johanna E. Kowalko, R. Peuss, Y. Yoshiyuki, Nicolas Rohner, Misty R. Riddle, Sunishka Thakur, Itzel Sifuentes-Romero, Clifford J. Tabin, Welsey C Warren, Suzanne E. McGaugh, Tina A. Graves-Lindsay, Zhiyuan Hu, Joshua B. Gross, Jeffrey T. Miller, Richard Borowsky, L. Hiller, Edward S. Rice, Milinn Kremitzki, Brian M. Carlson, Mathilda T.M. Mommersteeg, Alex C. Keene, Tyler E. Boggs, Chad Tomlinson, Bethany A. Stanhope
Identifying the genetic factors that underlie complex traits is central to understanding the mechanistic underpinnings of evolution. In nature, adaptation to severe environmental change, such as encountered following colonization of caves, has dramat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bffe69c40fc3371eb4fc89abb8d4014a
https://doi.org/10.1101/2020.07.06.189654
https://doi.org/10.1101/2020.07.06.189654
Publikováno v:
Current Opinion in Physiology
The adult human heart has a very poor capacity to repair itself following injury. During heart attack, an enormous amount of cardiac tissue is lost from ischaemia. Whilst a low level of proliferation exists within the heart, the rate is insufficient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a648fdbd213bb710a955314e1bf57186
Autor:
Jorge N. Domínguez, Gerard J.J. Boink, Rajiv A Mohan, Corrie de Gier-de Vries, Mathilda T.M. Mommersteeg, Lucile Miquerol, Vincent M. Christoffels, Vincent Wakker, Caroline Choquet, Arie O. Verkerk, Bastiaan J. Boukens
Publikováno v:
Development (Cambridge, England)
Development (Cambridge, England), Company of Biologists, 2018, 145 (17), pp.dev167361. ⟨10.1242/dev.167361⟩
Development (Cambridge, England), 145(17):dev167361. Company of Biologists Ltd
Development
Development (Cambridge, England), 2018, 145 (17), pp.dev167361. ⟨10.1242/dev.167361⟩
Development (Cambridge, England), Company of Biologists, 2018, 145 (17), pp.dev167361. ⟨10.1242/dev.167361⟩
Development (Cambridge, England), 145(17):dev167361. Company of Biologists Ltd
Development
Development (Cambridge, England), 2018, 145 (17), pp.dev167361. ⟨10.1242/dev.167361⟩
International audience; A small network of spontaneously active Tbx3+ cardiomyocytes forms the cardiac conduction system (CCS) in adults. Understanding the origin and mechanism of development of the CCS network are important steps towards disease mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e3e3279f98821d77d7ab95eef03bd0e
https://hal.archives-ouvertes.fr/hal-01993713
https://hal.archives-ouvertes.fr/hal-01993713
Autor:
Maurice J.B. van den Hoff, Bram van Wijk, Vincent M. Christoffels, Mathilda T.M. Mommersteeg, Julia Norden, Marianne Petry, Andreas Kispert, Karen Niederreither, Ekkehart Lausch, Christoph Englert, Thomas Grieskamp
Publikováno v:
Circulation research, 106(7), 1212-U97. Lippincott Williams and Wilkins
Rationale : The cardiac venous pole is a common focus of congenital malformations and atrial arrhythmias, yet little is known about the cellular and molecular mechanisms that regulate its development. The systemic venous return myocardium (sinus node
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8d242b7facf96ce815cf944ed4c748e
https://doi.org/10.1161/circresaha.110.217455
https://doi.org/10.1161/circresaha.110.217455
Autor:
Richard P. Harvey, Karin Schuster-Gossler, Mark-Oliver Trowe, Markus Bussen, Corrie de Gier-de Vries, Andreas Kispert, Owen W.J. Prall, Vincent M. Christoffels, Antoon F.M. Moorman, Alexandre T. Soufan, Mathilda T.M. Mommersteeg
Publikováno v:
Circulation research, 98(12), 1555-1563. Lippincott Williams and Wilkins
The venous pole of the mammalian heart is a structurally and electrically complex region, yet the lineage and molecular mechanisms underlying its formation have remained largely unexplored. In contrast to classical studies that attribute the origin o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aeec8261cb50934177cbf2baa1d7010f
https://doi.org/10.1161/01.res.0000227571.84189.65
https://doi.org/10.1161/01.res.0000227571.84189.65
Autor:
Maurice J.B. van den Hoff, Frederik J. de Lange, Mathilda T.M. Mommersteeg, Vincent M. Christoffels, Antoon F.M. Moorman, Robert H. Anderson, Alexandre T. Soufan
Publikováno v:
Circulation research, 99(4), 351-353. Lippincott Williams and Wilkins
Closure of the primary atrial foramen is achieved by fusion of the atrioventricular cushions with the mesenchymal cap on the leading edge of the muscular primary atrial septum. A fourth component involved is the vestibular spine, originally described
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::583054c47ee690adcad40a5507fd5ab4
https://doi.org/10.1161/01.res.0000238360.33284.a0
https://doi.org/10.1161/01.res.0000238360.33284.a0
Autor:
Alain Chédotal, Mathilda T.M. Mommersteeg, Mason L. Yeh, William D. Andrews, Pavol Zelina, Vincent M. Christoffels, John G. Parnavelas, Julia Norden, Andreas Kispert, Athena R. Ypsilanti
Publikováno v:
Circulation research, 112(3), 465-475. Lippincott Williams and Wilkins
Rationale: The Slit–Roundabout (Robo) signaling pathway has pleiotropic functions during Drosophila heart development. However, its role in mammalian heart development is largely unknown. Objective: To analyze the role of Slit–Robo signaling in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27e576be527018e54ced332eb1071fd7
http://ora.ox.ac.uk/objects/uuid:ca513d48-dd6a-4498-b0dc-60b03429f3bc
http://ora.ox.ac.uk/objects/uuid:ca513d48-dd6a-4498-b0dc-60b03429f3bc
Autor:
Klaartje van Engelen, Anne M. J. B. Smets, Marieke J.H. Baars, A S Paul van Trotsenburg, Jan Lam, Mathilda T.M. Mommersteeg, Barbara J. M. Mulder, Alex V. Postma, Vincent M. Christoffels, Aho Ilgun
Publikováno v:
PLoS ONE, 7(12):e52685. Public Library of Science
PLoS ONE
van Engelen, K, Mommersteeg, M T M, Baars, M J H, Lam, J, Ilgun, A, van Trotsenburg, A S P, Smets, A M J B, Christoffels, V M, Mulder, B J M & Postma, A V 2012, ' The Ambiguous Role of NKX2-5 Mutations in Thyroid Dysgenesis ', PLoS ONE, vol. 7, no. 12, e52685 . https://doi.org/10.1371/journal.pone.0052685
PLoS ONE, Vol 7, Iss 12, p e52685 (2012)
PLoS ONE, 7(12). Public Library of Science
PLoS ONE
van Engelen, K, Mommersteeg, M T M, Baars, M J H, Lam, J, Ilgun, A, van Trotsenburg, A S P, Smets, A M J B, Christoffels, V M, Mulder, B J M & Postma, A V 2012, ' The Ambiguous Role of NKX2-5 Mutations in Thyroid Dysgenesis ', PLoS ONE, vol. 7, no. 12, e52685 . https://doi.org/10.1371/journal.pone.0052685
PLoS ONE, Vol 7, Iss 12, p e52685 (2012)
PLoS ONE, 7(12). Public Library of Science
NKX2-5 is a homeodomain-containing transcription factor implied in both heart and thyroid development. Numerous mutations in NKX2-5 have been reported in individuals with congenital heart disease (CHD), but recently a select few have been associated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c23b0a02da773820e5f8ef21a5bbb73e
https://research.vumc.nl/en/publications/cd051619-f43e-406f-8c1c-37f9f52bda0a
https://research.vumc.nl/en/publications/cd051619-f43e-406f-8c1c-37f9f52bda0a