Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Mathijs Voorhoeve"'
Autor:
Shi Yun Yeo, Yoko Itahana, Alvin Kunyao Guo, Rachel Han, Kozue Iwamoto, Hung Thanh Nguyen, Yi Bao, Kai Kleiber, Ya Jun Wu, Boon Huat Bay, Mathijs Voorhoeve, Koji Itahana
Publikováno v:
eLife, Vol 5 (2016)
Genetic alterations which impair the function of the TP53 signaling pathway in TP53 wild-type human tumors remain elusive. To identify new components of this pathway, we performed a screen for genes whose loss-of-function debilitated TP53 signaling a
Externí odkaz:
https://doaj.org/article/81cca80787a441dfb2b58c6e42a290ba
Autor:
Edward S Y Wong, Sandhya Shekar, Claire H T Chan, Lewis Z Hong, Suk-Yean Poon, Toomas Silla, Clarabelle Lin, Vikrant Kumar, Sonia Davila, Mathijs Voorhoeve, Aye Aye Thike, Gay Hui Ho, Yoon Sim Yap, Puay Hoon Tan, Min-Han Tan, Peter Ang, Ann S G Lee
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0134408 (2015)
The National Comprehensive Cancer Network (NCCN) has proposed guidelines for the genetic testing of the BRCA1 and BRCA2 genes, based on studies in western populations. This current study assessed potential predictive factors for BRCA mutation probabi
Externí odkaz:
https://doaj.org/article/17fe3ee275054f9785a5cbd94d4b7ec0
Autor:
Patrick Tan, P. Mathijs Voorhoeve, Nallasivam Palanisamy, Sun-Young Rha, Kalpana Ramnarayanan, Julian Lee, Emmanuel Beillard, Iain BeeHuat Tan, Nian-Tao Deng, Chia-Huey Ooi, Kakoli Das, Angie Lay-Keng Tan, Hue-Kian Oh
Purpose: MicroRNAs (miRNA) play pivotal oncogenic and tumor-suppressor roles in several human cancers. We sought to discover novel tumor-suppressor miRNAs in gastric cancer (GC).Experimental Design: Using Agilent miRNA microarrays, we compared miRNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b868ccbaaee447140b26b1012bbcec81
https://doi.org/10.1158/1078-0432.c.6519584.v1
https://doi.org/10.1158/1078-0432.c.6519584.v1
Autor:
Patrick Tan, P. Mathijs Voorhoeve, Nallasivam Palanisamy, Sun-Young Rha, Kalpana Ramnarayanan, Julian Lee, Emmanuel Beillard, Iain BeeHuat Tan, Nian-Tao Deng, Chia-Huey Ooi, Kakoli Das, Angie Lay-Keng Tan, Hue-Kian Oh
Supplementary Figures S1-S4; Supplementary Table S1.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12bb0b94bf1f8bb0dce4baa8d8c0b5a9
https://doi.org/10.1158/1078-0432.22442966.v1
https://doi.org/10.1158/1078-0432.22442966.v1
Autor:
Patrick Tan, Koji Itahana, Boon Huat Bay, Puay Hoon Tan, Qiang Yu, Pieter Mathijs Voorhoeve, Steve Rozen, Anuradha Pandey, Aye Aye Thike, Shen Li Zhang, Yingnan Yu, Yonghui Wu, Na-Yu Chia, Zheng Deng Lei, Yoko Itahana, Lai Ling Cheng
PDF file - 484K, Table S1. Clinical Characteristics of the GC Cohort Analyzed in this Study. Table S2. Differentially-Regulated Genes in DZNep-Sensitive and Resistant Lines after DZNep Treatment. Table S3. Genomic Status of TP53 in Gastric Cancer Cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d5fb2fe62c86e2682f5a2baa9a556e0
https://doi.org/10.1158/1078-0432.22445472
https://doi.org/10.1158/1078-0432.22445472
Autor:
Patrick Tan, Koji Itahana, Boon Huat Bay, Puay Hoon Tan, Qiang Yu, Pieter Mathijs Voorhoeve, Steve Rozen, Anuradha Pandey, Aye Aye Thike, Shen Li Zhang, Yingnan Yu, Yonghui Wu, Na-Yu Chia, Zheng Deng Lei, Yoko Itahana, Lai Ling Cheng
Purpose: DZNep (3-deazaneplanocin A) depletes EZH2, a critical component of polycomb repressive complex 2 (PRC2), which is frequently deregulated in cancer. Despite exhibiting promising anticancer activity, the specific genetic determinants underlyin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d379e440c52982e0e6f8d9cb08b5b141
https://doi.org/10.1158/1078-0432.c.6520488
https://doi.org/10.1158/1078-0432.c.6520488
Autor:
Ygal Haupt, Giovanni Blandino, Alex Damalas, Mathijs Voorhoeve, Osnat Alsheich-Bartok, Inbal Mizrahi, Silvia di Agostino, Sue Haupt
Supplementary Figure 4 from Promyelocytic Leukemia Protein is Required for Gain of Function by Mutant p53
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cb6a7abbea89e87dc2011be6f69d9d3
https://doi.org/10.1158/0008-5472.22377933.v1
https://doi.org/10.1158/0008-5472.22377933.v1
Autor:
Ygal Haupt, Giovanni Blandino, Alex Damalas, Mathijs Voorhoeve, Osnat Alsheich-Bartok, Inbal Mizrahi, Silvia di Agostino, Sue Haupt
Supplementary Figure 1 from Promyelocytic Leukemia Protein is Required for Gain of Function by Mutant p53
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b23c716aa207796bc306873b217af19d
https://doi.org/10.1158/0008-5472.22377942.v1
https://doi.org/10.1158/0008-5472.22377942.v1
Autor:
Ygal Haupt, Giovanni Blandino, Alex Damalas, Mathijs Voorhoeve, Osnat Alsheich-Bartok, Inbal Mizrahi, Silvia di Agostino, Sue Haupt
Supplementary Figure 2 from Promyelocytic Leukemia Protein is Required for Gain of Function by Mutant p53
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a5b25776495c5f74f15e879a8b6b423
https://doi.org/10.1158/0008-5472.22377939
https://doi.org/10.1158/0008-5472.22377939
Autor:
Ygal Haupt, Giovanni Blandino, Alex Damalas, Mathijs Voorhoeve, Osnat Alsheich-Bartok, Inbal Mizrahi, Silvia di Agostino, Sue Haupt
Supplementary Figure 3 from Promyelocytic Leukemia Protein is Required for Gain of Function by Mutant p53
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::746b3588b64408ae3596da5fcd51aaa9
https://doi.org/10.1158/0008-5472.22377936.v1
https://doi.org/10.1158/0008-5472.22377936.v1