Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Mathijs G A Broeren"'
Autor:
Mathijs G A Broeren, Marieke de Vries, Miranda B Bennink, Peter L E M van Lent, Peter M van der Kraan, Marije I Koenders, Rogier M Thurlings, Fons A J van de Loo
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0167076 (2016)
Osteoarthritis (OA) is a degenerative joint disease affecting cartilage and is the most common form of arthritis worldwide. One third of OA patients have severe synovitis and less than 10% have no evidence of synovitis. Moreover, synovitis is predict
Externí odkaz:
https://doaj.org/article/bc6c8d22553b4ed388e67602cb7f9c54
Autor:
Bartijn C H Pieters, Onno J Arntz, Miranda B Bennink, Mathijs G A Broeren, Arjan P M van Caam, Marije I Koenders, Peter L E M van Lent, Wim B van den Berg, Marieke de Vries, Peter M van der Kraan, Fons A J van de Loo
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0121123 (2015)
ScopeExtracellular vesicles, including exosomes, have been identified in all biological fluids and rediscovered as an important part of the intercellular communication. Breast milk also contains extracellular vesicles and the proposed biological func
Externí odkaz:
https://doaj.org/article/f09e52a2843b43f2bebd39101869033a
Autor:
Claire E. J. Waterborg, Silke Beermann, Mathijs G. A. Broeren, Miranda B. Bennink, Marije I. Koenders, Peter L. E. M. van Lent, Wim B. van den Berg, Peter M. van der Kraan, Fons A. J. van de Loo
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
ObjectiveRheumatoid arthritis (RA) is a chronic and progressive joint disease. It appears that anti-inflammatory feedback mechanisms that could restrain joint inflammation and restore homeostasis are insufficient to perform this control. In this stud
Externí odkaz:
https://doaj.org/article/ca6733155fe54ecab960104d139acfd6
Autor:
Mathijs G A Broeren, Jing J Wang, Giulia Balzaretti, Patricia J T A Groenen, Barbera D C van Schaik, Tim Chataway, Charlotte Kaffa, Sander Bervoets, Konnie M Hebeda, Gergana Bounova, Ger J M Pruijn, Thomas P Gordon, Niek De Vries, Rogier M Thurlings
Publikováno v:
Annals of the Rheumatic Diseases, 81, 644-652
Annals of the Rheumatic Diseases, 81, 5, pp. 644-652
Annals of the Rheumatic Diseases, 81(5):221604, 644-652. BMJ Publishing Group
Annals of the rheumatic diseases, 81(5):221604, 644-652. BMJ Publishing Group
Broeren, M G A, Wang, J J, Balzaretti, G, Groenen, P J T A, van Schaik, B D C, Chataway, T, Kaffa, C, Bervoets, S, Hebeda, K M, Bounova, G, Pruijn, G J M, Gordon, T P, de Vries, N & Thurlings, R M 2022, ' Proteogenomic analysis of the autoreactive B cell repertoire in blood and tissues of patients with Sjögren's syndrome ', Annals of the Rheumatic Diseases, vol. 81, no. 5, 221604, pp. 644-652 . https://doi.org/10.1136/annrheumdis-2021-221604
Annals of the Rheumatic Diseases, 81, 5, pp. 644-652
Annals of the Rheumatic Diseases, 81(5):221604, 644-652. BMJ Publishing Group
Annals of the rheumatic diseases, 81(5):221604, 644-652. BMJ Publishing Group
Broeren, M G A, Wang, J J, Balzaretti, G, Groenen, P J T A, van Schaik, B D C, Chataway, T, Kaffa, C, Bervoets, S, Hebeda, K M, Bounova, G, Pruijn, G J M, Gordon, T P, de Vries, N & Thurlings, R M 2022, ' Proteogenomic analysis of the autoreactive B cell repertoire in blood and tissues of patients with Sjögren's syndrome ', Annals of the Rheumatic Diseases, vol. 81, no. 5, 221604, pp. 644-652 . https://doi.org/10.1136/annrheumdis-2021-221604
ObjectiveTo comparatively analyse the aberrant affinity maturation of the antinuclear and rheumatoid factor (RF) B cell repertoires in blood and tissues of patients with Sjögren’s syndrome (SjS) using an integrated omics workflow.MethodsPeptide se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e9b2d6106ae5cd4d06cca576bf91c87
http://hdl.handle.net/2066/249151
http://hdl.handle.net/2066/249151
Autor:
Irene Di Ceglie, Fons A. J. van de Loo, Mathijs G A Broeren, Peter Laverman, Daphne N. Dorst, Peter L E M van Lent, Rogier M Thurlings, Marije I. Koenders, Peter M. van der Kraan, Claire E J Waterborg
Publikováno v:
Oral Presentations.
Background Many experiments to study inflammation, hyperplasia, and fibrosis in the synovium have been performed in animal models of RA and OA. However, the predictive value of these models for the screening of potential drugs in RA is variable and f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33a62ea15be7684a62ffed5199014a4f
https://doi.org/10.1136/annrheumdis-2019-eular.2059
https://doi.org/10.1136/annrheumdis-2019-eular.2059
Autor:
Peter L E M van Lent, Arjen B. Blom, Fons A. J. van de Loo, Peter M. van der Kraan, Wim B. van den Berg, Mathijs G A Broeren, Marije I. Koenders, Onno J. Arntz, Miranda B. Bennink, Marieke de Vries
Publikováno v:
Human Gene Therapy, 27, 244-54
Human Gene Therapy, 27, 3, pp. 244-54
Human Gene Therapy, 27, 3, pp. 244-54
Contains fulltext : 165957.pdf (Author’s version postprint ) (Open Access) Disease-inducible promoters for the treatment of rheumatoid arthritis (RA) have the potential to provide regulated expression of therapeutic proteins in arthritic joints. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2b83717473e07dff3c06c43dfe9a8ab
https://hdl.handle.net/2066/165957
https://hdl.handle.net/2066/165957
Autor:
Wim B. van den Berg, Mathijs G A Broeren, Peter M. van der Kraan, Irene Di Ceglie, Peter L E M van Lent, Miranda B. Bennink, Marije I. Koenders, Esmeralda N. Blaney Davidson, Fons A. J. van de Loo
Publikováno v:
PeerJ
PeerJ, Vol 6, p e4771 (2018)
PeerJ, 6
PeerJ, Vol 6, p e4771 (2018)
PeerJ, 6
Objective Tumor necrosis factor-inducible gene 6 (TSG-6) has anti-inflammatory and chondroprotective effects in mouse models of inflammatory arthritis. Because cartilage damage and inflammation are also observed in osteoarthritis (OA), we determined
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6dfb4843989d657f3c98b8bfb33b153
http://europepmc.org/articles/PMC5984587
http://europepmc.org/articles/PMC5984587
Autor:
Wim B. van den Berg, Peter M. van der Kraan, Mathijs G A Broeren, Miranda B. Bennink, Marije I. Koenders, Peter L E M van Lent, Onno J. Arntz, Marina C. Oliveira, Bartijn C. H. Pieters, Marieke de Vries, Fons A. J. van de Loo
Publikováno v:
Molecular Nutrition & Food Research (Formerly Nahrung/Food), 59, 9, pp. 1701-12
Molecular Nutrition & Food Research (Formerly Nahrung/Food), 59, 1701-12
Molecular Nutrition & Food Research (Formerly Nahrung/Food), 59, 1701-12
Contains fulltext : 153549.pdf (Publisher’s version ) (Closed access) SCOPE: This study shows the effect of bovine milk derived extracellular vesicles (BMEVs) on spontaneous polyarthritis in IL-1Ra-deficient mice and collagen-induced arthritis. MET
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::524a9ef12ad0ed44748be1abd4a3ae92
https://hdl.handle.net/2066/153549
https://hdl.handle.net/2066/153549
Autor:
Wim B. van den Berg, Mathijs G A Broeren, Fons A. J. van de Loo, Marije I. Koenders, Claire E J Waterborg, Esmeralda N. Blaney Davidson, Peter L E M van Lent, Peter M. van der Kraan
Publikováno v:
Rheumatology, 58, 536-546
Rheumatology, 58, 3, pp. 536-546
Rheumatology, 58, 3, pp. 536-546
OBJECTIVE To investigate the role of AXL, a member of the anti-inflammatory TYRO3, AXL MER (TAM) receptor family, in arthritis. METHODS KRN serum transfer arthritis was induced in Axl-/- and wild-type mice. Knee and ankle joints were scored macro- an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfd5b4548b80bba5b99db48b8134748a
https://pubmed.ncbi.nlm.nih.gov/30508140
https://pubmed.ncbi.nlm.nih.gov/30508140
Autor:
Onno J. Arntz, Miranda B. Bennink, Fons Aj van de Loo, Wim B. van den Berg, Mathijs G A Broeren
Publikováno v:
Novel technologies.
Background No disease-modifying drugs are available for osteoarthritis (OA). Although the aetiology is still unknown, inflammation is indicated to be involved in the disease pathogenesis in many patients. Gene therapy can enable transduced joint cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c085b39c1a1005b858feaddc5c9ad5f1
https://doi.org/10.1136/annrheumdis-2016-211053.7
https://doi.org/10.1136/annrheumdis-2016-211053.7