Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Mathieu Sertorio"'
Autor:
Emily C Daugherty, Anthony Mascia, Yong Zhang, Eunsin Lee, Zhiyan Xiao, Mathieu Sertorio, Jennifer Woo, Claire McCann, Kenneth Russell, Lisa Levine, Ricky Sharma, Deepak Khuntia, Jeffrey Bradley, Charles B Simone II, John Perentesis, John Breneman
Publikováno v:
JMIR Research Protocols, Vol 12, p e41812 (2023)
BackgroundIn preclinical studies, FLASH therapy, in which radiation delivered at ultrahigh dose rates of ≥40 Gy per second, has been shown to cause less injury to normal tissues than radiotherapy delivered at conventional dose rates. This paper des
Externí odkaz:
https://doaj.org/article/d83b0adcb7254b07ae6d088f07fde493
Autor:
Michael T. Williams, Chiho Sugimoto, Samantha L. Regan, Emily M. Pitzer, Adam L. Fritz, Anthony E. Mascia, Mathieu Sertorio, Ralph E. Vatner, John P. Perentesis, Charles V. Vorhees
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-20 (2020)
Abstract Proton radiotherapy causes less off-target effects than X-rays but is not without effect. To reduce adverse effects of proton radiotherapy, a model of cognitive deficits from conventional proton exposure is needed. We developed a model empha
Externí odkaz:
https://doaj.org/article/5d32edd717014b9596a855396e69d6d1
Autor:
Michael T Williams, Chiho Sugimoto, Samantha L Regan, Emily M Pitzer, Adam L Fritz, Mathieu Sertorio, Anthony E Mascia, Ralph E Vatner, John P Perentesis, Charles V Vorhees
Publikováno v:
PLoS ONE, Vol 17, Iss 9, p e0274007 (2022)
Recent studies suggest that ultra-high dose rates of proton radiation (>40 Gy/s; FLASH) confer less toxicity to exposed healthy tissue and reduce cognitive decline compared with conventional radiation dose rates (~1 Gy/s), but further preclinical dat
Externí odkaz:
https://doaj.org/article/8cca211bfd4841748d9af0addd081e91
Publikováno v:
Stem Cell Reports, Vol 8, Iss 5, Pp 1242-1255 (2017)
Hematopoietic stem cell (HSC) defects can cause repopulating impairment leading to hematologic diseases. To target HSC deficiency in a disease setting, we exploited the repopulating defect of Fanconi anemia (FA) HSCs to conduct an in vivo short hairp
Externí odkaz:
https://doaj.org/article/d6d5c3281596424fa2c7b9e328fceb6e
Autor:
Audrey Romano, Xunya Hou, Mathieu Sertorio, Hélia Dessein, Sandrine Cabantous, Pablo Oliveira, Jun Li, Sandrine Oyegue, Violaine Arnaud, Xinsong Luo, Martine Daujat-Chavanieu, Odette Mariani, Xavier Sastre, Anne-Marie Dombey, Hongbin He, Yuesheng Li, Alain Dessein
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 2, p e0004454 (2016)
Externí odkaz:
https://doaj.org/article/53ddc2d4d9774d9d81749cbf9c4351e6
Autor:
Audrey Romano, Xunya Hou, Mathieu Sertorio, Hélia Dessein, Sandrine Cabantous, Pablo Oliveira, Jun Li, Sandrine Oyegue, Violaine Arnaud, Xinsong Luo, Martine Daujat-Chavanieu, Odette Mariani, Xavier Sastre, Anne-Marie Dombey, Hongbin He, Yuesheng Li, Alain Dessein
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 1, p e0004306 (2016)
Schistosoma eggs cause chronic liver inflammation and a complex disease characterized by hepatic fibrosis (HF) and splenomegaly (SplM). FOXP3+ Tregs could regulate inflammation, but it is unclear where these cells are produced and what roles they pla
Externí odkaz:
https://doaj.org/article/e7365a8449ea42b6baca45782d2c1893
Publikováno v:
Genomics Data, Vol 4, Iss C, Pp 148-149 (2015)
Functional maintenance of hematopoietic stem cells (HSCs) is constantly challenged by stresses like DNA damage and oxidative stress. Foxo factors particularly Foxo3a function to regulate the self-renewal of HSCs and contribute to the maintenance of t
Externí odkaz:
https://doaj.org/article/0cafc2cbe8164403907715b8b8e4014c
Publikováno v:
Radiation Research. 199
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7acf2e7681997a76f7ed4dde9cb4896
https://doi.org/10.1667/rade-22-00210.1
https://doi.org/10.1667/rade-22-00210.1
Publikováno v:
Cancers, Vol 14, Iss 514, p 514 (2022)
Although radiation therapy (RT) is one of the mainstays of head and neck cancer (HNC) treatment, innovative approaches are needed to further improve treatment outcomes. A significant challenge has been to design delivery strategies that focus high do
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eb8aba20ce37bdb1641febc921c7dd2
https://www.mdpi.com/2072-6694/14/3/514
https://www.mdpi.com/2072-6694/14/3/514
Autor:
Anthony E. Mascia, Emily C. Daugherty, Yongbin Zhang, Eunsin Lee, Zhiyan Xiao, Mathieu Sertorio, Jennifer Woo, Lori R. Backus, Julie M. McDonald, Claire McCann, Kenneth Russell, Lisa Levine, Ricky A. Sharma, Dee Khuntia, Jeffrey D. Bradley, Charles B. Simone, John P. Perentesis, John C. Breneman
Publikováno v:
JAMA Oncology. 9:62
ImportanceTo our knowledge, there have been no clinical trials of ultra-high-dose-rate radiotherapy delivered at more than 40 Gy/sec, known as FLASH therapy, nor first-in-human use of proton FLASH.ObjectivesTo assess the clinical workflow feasibility
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc2d960297f20f55ee7b7999a9129163
https://doi.org/10.1001/jamaoncol.2022.5843
https://doi.org/10.1001/jamaoncol.2022.5843