Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Mathieu N, Flamand"'
Publikováno v:
Annual Review of Biochemistry. 92
Over the past decade, mRNA modifications have emerged as important regulators of gene expression control in cells. Fueled in large part by the development of tools for detecting RNA modifications transcriptome wide, researchers have uncovered a diver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c48460030ed1fc0f1972abb18711cc69
https://doi.org/10.1146/annurev-biochem-052521-035330
https://doi.org/10.1146/annurev-biochem-052521-035330
Publikováno v:
Genesdevelopment. 36(17-18)
RNA-binding proteins (RBPs) regulate nearly every aspect of mRNA processing and are important regulators of gene expression in cells. However, current methods for transcriptome-wide identification of RBP targets are limited since they examine only a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13199c5b009eb0edb6d7fc2cd1615b07
https://pubmed.ncbi.nlm.nih.gov/36302554
https://pubmed.ncbi.nlm.nih.gov/36302554
Autor:
Nahum Sonenberg, Mathieu N. Flamand, James A. Wohlschlegel, Alice M Lambert, Vinay K. Mayya, Thomas F. Duchaine, Seyed Mehdi Jafarnejad
Publikováno v:
Mayya, V K, Flamand, M N, Lambert, A M, Jafarnejad, S M, Wohlschlegel, J A, Sonenberg, N & Duchaine, T F 2021, ' microRNA-mediated translation repression through GYF-1 and IFE-4 in C. elegans development ', Nucleic Acids Research . https://doi.org/10.1093/nar/gkab162
Nucleic Acids Research
Nucleic Acids Research
microRNA (miRNA)-mediated gene silencing is enacted through the recruitment of effector proteins that direct translational repression or degradation of mRNA targets, but the relative importance of their activities for animal development remains unkno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab4905c393cc28ee1e390536c93351b1
https://doi.org/10.1093/nar/gkab162
https://doi.org/10.1093/nar/gkab162
Autor:
Mathieu N Flamand, Kate D Meyer
Publikováno v:
Nucleic acids research. 50(8)
The transport of mRNAs to distal subcellular compartments is an important component of spatial gene expression control in neurons. However, the mechanisms that control mRNA localization in neurons are not completely understood. Here, we identify the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38d2da746fb12bd9894493e0e7c2d632
https://pubmed.ncbi.nlm.nih.gov/35438793
https://pubmed.ncbi.nlm.nih.gov/35438793
Autor:
Seung H, Choi, Mathieu N, Flamand, Bei, Liu, Huanyu, Zhu, Meghan, Hu, Melanie, Wang, Jonathon, Sewell, Christopher L, Holley, Hashim M, Al-Hashimi, Kate D, Meyer
Publikováno v:
Cell reports. 40(9)
N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::05348121f15a26387c09245165747cc6
https://pubmed.ncbi.nlm.nih.gov/36044854
https://pubmed.ncbi.nlm.nih.gov/36044854
Autor:
Kate D. Meyer, Mathieu N Flamand
Publikováno v:
Curr Opin Neurobiol
RNA modifications, collectively referred to as “the epitranscriptome,” have recently emerged as a pervasive feature of cellular mRNAs which have diverse impacts on gene expression. In the last several years, technological advances improving our a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::698e1f3ae16976a2763f7262be5a34ea
https://doi.org/10.1016/j.conb.2019.04.007
https://doi.org/10.1016/j.conb.2019.04.007
Autor:
Bin Yu, Matthew Eroglu, Thomas F. Duchaine, Samuel J Krempel, Mathieu N Flamand, Eric M Chapman, Anh Tran, W. Brent Derry
Publikováno v:
Cell Death and Differentiation
Apoptosis is a genetically programmed cell death process with profound roles in development and disease. MicroRNAs modulate the expression of many proteins and are often deregulated in human diseases, such as cancer. C. elegans germ cells undergo apo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::779f0c0922cf90a153f65cb2f5921b58
https://doi.org/10.1038/s41418-019-0325-6
https://doi.org/10.1038/s41418-019-0325-6
Autor:
Seung H. Choi, Mathieu N. Flamand, Bei Liu, Huanyu Zhu, Meghan Hu, Melanie Wang, Jonathon Sewell, Christopher L. Holley, Hashim M. Al-Hashimi, Kate D. Meyer
Publikováno v:
Cell Reports. 40:111293
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f39dea8c4a48a3df8bcd725da7dde637
https://doi.org/10.1016/j.celrep.2022.111293
https://doi.org/10.1016/j.celrep.2022.111293
Autor:
Ahmet C. Berkyurek, Eric A. Miska, Mathieu N. Flamand, Mihail Sarov, Stephanie Merrett, Ajay A. Vashisht, Alexandra Lewis, James A. Wohlschlegel, Ahilya N. Sawh, Thomas F. Duchaine, Andre Greiner
Publikováno v:
Mol Cell
Summary Nuclear RNA interference (RNAi) pathways work together with histone modifications to regulate gene expression and enact an adaptive response to transposable RNA elements. In the germline, nuclear RNAi can lead to trans-generational epigenetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc1bfa604efda46eab4db42a0209a34b
https://www.repository.cam.ac.uk/handle/1810/318860
https://www.repository.cam.ac.uk/handle/1810/318860
Publikováno v:
Mol Cell
N(6)-methyladenosine (m(6)A) is an abundant RNA modification that plays critical roles in RNA regulation and cellular function. Global m(6)A profiling has revealed important aspects of m(6)A distribution and function, but to date such studies have be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c71c6707824c24f8f846a20f337db53
https://doi.org/10.1016/j.molcel.2021.12.038
https://doi.org/10.1016/j.molcel.2021.12.038