Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Mathieu Herman"'
Autor:
Tal Nuriel, Sergio L. Angulo, Usman Khan, Archana Ashok, Qiuying Chen, Helen Y. Figueroa, Sheina Emrani, Li Liu, Mathieu Herman, Geoffrey Barrett, Valerie Savage, Luna Buitrago, Efrain Cepeda-Prado, Christine Fung, Eliana Goldberg, Steven S. Gross, S. Abid Hussaini, Herman Moreno, Scott A. Small, Karen E. Duff
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
The APOE4 allele is the leading risk factor for late-onset Alzheimer’s disease, but how it might contribute to the disease is not clear. Here the authors show that a mouse expressing the human APOE4 allele displays hyperactivity in the entorhinal c
Externí odkaz:
https://doaj.org/article/91098ce8e7d943429a161e6bc0ddcf3e
Autor:
Hongjun Fu, S Abid Hussaini, Susanne Wegmann, Caterina Profaci, Jacob D Daniels, Mathieu Herman, Sheina Emrani, Helen Y Figueroa, Bradley T Hyman, Peter Davies, Karen E Duff
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0159463 (2016)
3D volume imaging using iDISCO+ was applied to observe the spatial and temporal progression of tau pathology in deep structures of the brain of a mouse model that recapitulates the earliest stages of Alzheimer's disease (AD). Tau pathology was compar
Externí odkaz:
https://doaj.org/article/dd6c376d0fad48e2bc7f2456a4cdbcac
Autor:
Li Liu, Ian J. Orozco, Emmanuel Planel, Yi Wen, Alexis Bretteville, Pavan Krishnamurthy, Lili Wang, Mathieu Herman, Helen Figueroa, W. Haung Yu, Ottavio Arancio, Karen Duff
Publikováno v:
Neurobiology of Disease, Vol 31, Iss 1, Pp 46-57 (2008)
In the last decade, multiple lines of transgenic APP overexpressing mice have been created that recapitulate certain aspects of Alzheimer's disease (AD). However, none of the previously reported transgenic APP overexpressing rat models developed AD-l
Externí odkaz:
https://doaj.org/article/176eaee9e6aa4b5a841142b79871d76d
Autor:
Alice Zambon, Laura Cuenca Rico, Mathieu Herman, Anna Gundacker, Amina Telalovic, Lisa-Marie Hartenberger, Rebekka Kuehn, Roman A. Romanov, S. Abid Hussaini, Tibor Harkany, Daniela D. Pollak
Publikováno v:
Molecular Psychiatry.
Immune activation is one of the most common complications during pregnancy, predominantly evoked by viral infections. Nevertheless, how immune activation affects mother–offspring relationships postpartum remains unknown. Here, by using the polyinos
Autor:
Mathieu Hermann COULIBALY
Publikováno v:
Ziglôbitha, Vol 02, Iss 08, Pp 555-572 (2023)
Abstract : How do student motorcyclists and their parents manage the risk of accidents in order to guarantee the safety of the first nommed on the roads of Korhogo? Attempting to answer this research question, this article has shown that students dri
Externí odkaz:
https://doaj.org/article/74c9992fdc0541788f75fea1b2b9c0a0
Autor:
Luna Buitrago, Sheina Emrani, Karen Duff, Steven S. Gross, Mathieu Herman, Eliana Goldberg, Valerie Savage, Herman Moreno, Usman A. Khan, Scott A. Small, Christine Fung, Helen Y. Figueroa, Efrain Cepeda-Prado, Tal Nuriel, Archana Ashok, Geoffrey Barrett, Sergio Angulo, S. Abid Hussaini, Li Liu, Qiuying Chen
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Nature Communications
Nature Communications
The ε4 allele of apolipoprotein E (APOE) is the dominant genetic risk factor for late-onset Alzheimer’s disease (AD). However, the reason APOE4 is associated with increased AD risk remains a source of debate. Neuronal hyperactivity is an early phe
Autor:
Mathieu Herman, Stylianos E. Antonarakis, Elizabeta Micevska, Joseph H. Lee, Ira T. Lott, Geoffrey Barrett, Rong Cheng, Eden Nahmani, S. Abid Hussaini, Catherine Marquer, André Miguel Lopes Miranda, Gaëlle Fontaine, Ivonne Z. Jimenez-Velazquez, Elizabeth Head, Gilbert Di Paolo, Marie-Claude Potier, Frederick A. Schmitt
Publikováno v:
Cell reports
Cell reports, vol 23, iss 10
Cell Reports
Cell Reports, Elsevier Inc, 2018, 23 (10), pp.2967-2975. ⟨10.1016/j.celrep.2018.05.011⟩
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Cell reports, vol 23, iss 10
Cell Reports
Cell Reports, Elsevier Inc, 2018, 23 (10), pp.2967-2975. ⟨10.1016/j.celrep.2018.05.011⟩
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
The phosphoinositide phosphatase synaptojanin 1 (SYNJ1) is a key regulator of synaptic function. We first tested whether SYNJ1 contributes to phenotypic variations in familial Alzheimer's disease (FAD) and show that SYNJ1 polymorphisms are associated
Autor:
Mathieu Herman, Eliana Goldberg, S. Abid Hussaini, Eden Nahmani, Sheina Emrani, Karen Duff, Helen Y. Figueroa, Geoffrey Barrett, Gustavo A. Rodriguez, Hongjun Fu
Summary The earliest stages of Alzheimer's disease (AD) are characterized by the formation of mature tangles in the entorhinal cortex and disorientation and confusion when navigating familiar places. The medial entorhinal cortex (MEC) contains specia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4688ada7bfc4f06f3375ab8638f0a8c3
https://europepmc.org/articles/PMC5363269/
https://europepmc.org/articles/PMC5363269/
Autor:
Yang Han, Maria Eleni Karakatsani, Amanda Buch, Tara Kugelman, Mathieu Herman, Shutao Wang, Elisa E. Konofagou, S. Abid Hussaini, Karen Duff
Publikováno v:
Scientific Reports
Optogenetics, a widely used technique in neuroscience research, is often limited by its invasive nature of application. Here, we present a noninvasive, ultrasound-based technique to introduce optogenetic channels into the brain by temporarily opening
Autor:
T Bobes-Bascaran, Shufen Chen, Mathieu Herman, Concepcion Conejero-Goldberg, Peter Davies, Thomas M. Hyde, Jesus J. Gomar, Terry E. Goldberg, Joel E. Kleinman
Publikováno v:
Molecular Psychiatry. 19:1243-1250
The common APOE2 gene variant is neuroprotective against Alzheimer's disease (AD) and reduces risk by nearly 50%. However, the mechanisms by which APOE2 confers neuroprotection are largely unknown. Here we showed that ApoE protein abundance in human