Zobrazeno 1 - 10 of 22 pro vyhledávání: '"Mathieu Galibert"'
1
Akademický článek
Lanthanide DO3A-Complexes Bearing Peptide Substrates: The Effect of Peptidic Side Chains on Metal Coordination and Relaxivity
Autor: Sophie Laine, Jean-François Morfin, Mathieu Galibert, Vincent Aucagne, Célia S. Bonnet, Éva Tóth
Publikováno v: Molecules, Vol 26, Iss 8, p 2176 (2021)
Two DO3A-type ligands conjugated to substrates of urokinase (L3) and caspase-3 (L4) via a propyl-amide linker were synthesized and their lanthanide(III) (Ln3+) complexes studied. A model compound without peptide substrate (L2) and an amine derivative
Externí odkaz: https://doaj.org/article/86616a63cf2f461098ff3b4d296837ce
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2
Akademický článek
MCH-R1 Antagonist GPS18169, a Pseudopeptide, Is a Peripheral Anti-Obesity Agent in Mice
Autor: Jean A. Boutin, Magali Jullian, Lukasz Frankiewicz, Mathieu Galibert, Philippe Gloanec, Thierry Le Diguarher, Philippe Dupuis, Amber Ko, Laurent Ripoll, Marc Bertrand, Anne Pecquery, Gilles Ferry, Karine Puget
Publikováno v: Molecules, Vol 26, Iss 5, p 1291 (2021)
Melanin-concentrating hormone (MCH) is a 19 amino acid long peptide found in the brain of animals, including fishes, batrachians, and mammals. MCH is implicated in appetite and/or energy homeostasis. Antagonists at its receptor (MCH-R1) could be majo
Externí odkaz: https://doaj.org/article/27505378d23142a9af54bb2688ef4401
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3
Fluorescent Peptide Biosensor for Probing CDK6 Kinase Activity in Lung Cancer Cell Extracts
Autor: Mathieu Galibert, Christophe Blanquart, Morgan Pellerano, Karine Puget, Magali Jullian, Sebastien Diot, Jessica Soamalala, May C. Morris
Publikováno v: ChemBioChem
ChemBioChem, Wiley-VCH Verlag, 2020, Online ahead of print. ⟨10.1002/cbic.202000677⟩
ChemBioChem, 2020, Online ahead of print. ⟨10.1002/cbic.202000677⟩
International audience; CDK6 kinase regulates cell cycle progression in G1, together with CDK4, but has cell-, tissue- and developmentally-distinct functions associated with transcription, angiogenesis and metabolism. Although CDK6 constitutes an att
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0af4ae050efbed28bb6babbeb9dbd686
https://doi.org/10.1002/cbic.202000677
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5
Lanthanide DO3A-Complexes Bearing Peptide Substrates: The Effect of Peptidic Side Chains on Metal Coordination and Relaxivity
Autor: Célia S. Bonnet, Vincent Aucagne, Mathieu Galibert, Jean-François Morfin, Éva Tóth, Sophie Laine
Publikováno v: Molecules
Volume 26
Issue 8
Molecules, Vol 26, Iss 2176, p 2176 (2021)
Molecules, 2021, 26 (8), pp.2176. ⟨10.3390/molecules26082176⟩
Molecules, MDPI, 2021, 26 (8), pp.2176. ⟨10.3390/molecules26082176⟩
Two DO3A-type ligands conjugated to substrates of urokinase (L3) and caspase-3 (L4) via a propyl-amide linker were synthesized and their lanthanide(III) (Ln3+) complexes studied. A model compound without peptide substrate (L2) and an amine derivative
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b81d7fa3037603763abcd2a8256a192
http://europepmc.org/articles/PMC8069257
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6
MCH-R1 Antagonist GPS18169, a Pseudopeptide, Is a Peripheral Anti-Obesity Agent in Mice
Autor: Marc Bertrand, Anne Pecquery, Mathieu Galibert, Laurent Ripoll, Lukasz Frankiewicz, Magali Jullian, Karine Puget, Gilles Ferry, Philippe Gloanec, Thierry Le Diguarher, Amber Ko, Philippe Dupuis, Jean A. Boutin
Publikováno v: Molecules
Volume 26
Issue 5
Molecules, Vol 26, Iss 1291, p 1291 (2021)
Melanin-concentrating hormone (MCH) is a 19 amino acid long peptide found in the brain of animals, including fishes, batrachians, and mammals. MCH is implicated in appetite and/or energy homeostasis. Antagonists at its receptor (MCH-R1) could be majo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c542f40a5cdc62352f63c463d9165d3f
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7
Determination of the Rituximab Binding Site to the CD20 Epitope Using SPOT Synthesis and Surface Plasmon Resonance Analyses
Autor: Francisco Santos-Schneider, Mathieu Galibert, Christophe Nguyen, Rémy Lartia, Didier Boturyn, Gudrun Aldrian, Jérôme Dejeu, Liliane Coche-Guérente, Franck Molina, Laure Bar
Publikováno v: Analytical Chemistry
Analytical Chemistry, American Chemical Society, In press, 93 (17), pp.6865-6872. ⟨10.1021/acs.analchem.1c00960⟩
Antibodies not only play a major role in clinical diagnostics and biopharmaceutical analysis but also are a class of drugs that are regularly used to treat numerous diseases. The identification of antibody-epitope binding sites is then of great inter
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec301978fdb380fc22a15275add60c78
http://hdl.handle.net/20.500.12278/33397
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8
Imaging of extracellular cathepsin S activity by a selective near infrared fluorescence substrate-based probe
Autor: Mylène Wartenberg, Ahlame Saidi, Mathieu Galibert, Vincent Aucagne, Alix Joulin-Giet, Gilles Lalmanach, Christopher J. Scott, Julien Burlaud-Gaillard, Agnès F. Delmas, Fabien Lecaille
Publikováno v: Biochimie
Biochimie, Elsevier, 2019, ⟨10.1016/j.biochi.2019.03.013⟩
Biochimie, 2019, 166, pp.84-93. ⟨10.1016/j.biochi.2019.03.013⟩
International audience; We designed a near-infrared fluorescent substrate-based probe (SBP), termed MG101, for monitoring extracellular cathepsin S (CatS) activity. We conceived a fused peptide hairpin loop-structure, combining a CatS recognition dom
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c30922a20f92e3d2404edaef0e51b62
https://hal.archives-ouvertes.fr/hal-02088627
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9
A Helping Hand to Overcome Solubility Challenges in Chemical Protein Synthesis
Autor: Michael S. Kay, George H. Lorimer, Mark E. Petersen, Mathieu Galibert, Vincent Aucagne, Michael T. Jacobsen, Xiang Ye
Publikováno v: Journal of the American Chemical Society
Journal of the American Chemical Society, American Chemical Society, 2016, 138 (36), pp.11775-11782. ⟨10.1021/jacs.6b05719⟩
International audience; Although native chemical ligation (NCL) and related chemoselective ligation approaches provide an elegant method to stitch together unprotected peptides, the handling and purification of insoluble and aggregation-prone peptide
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e2562cd5086464af1d70b58cd9ff772
https://hal.archives-ouvertes.fr/hal-01407028
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10
A synthetic kisspeptin analog that triggers ovulation and advances puberty
Autor: Vincent Aucagne, Alain Caraty, Xinhuai Liu, Jean-Baptiste Madinier, Caroline Decourt, Vincent Robert, Didier Lomet, Karine Anger, Mathieu Galibert, Hugues Dardente, Greg M. Anderson, Allan E. Herbison, Massimiliano Beltramo, Agnès F. Delmas
Publikováno v: Scientific Reports
Scientific Reports, Nature Publishing Group, 2016, 6, pp.26908. ⟨10.1038/srep26908⟩
Scientific Reports, 2016, 6 (1), pp.26908. ⟨10.1038/srep26908⟩
Scientific Reports, Nature Publishing Group, 2016, 6 (1), pp.26908. ⟨10.1038/srep26908⟩
Scientific Reports, Nature Publishing Group, 2016, 6 (1), pp.1-10. ⟨10.1038/srep26908⟩
Scientific Reports (6), 1-10. (2016)
The neuropeptide kisspeptin and its receptor, KiSS1R, govern the reproductive timeline of mammals by triggering puberty onset and promoting ovulation by stimulating gonadotrophin-releasing hormone (GnRH) secretion. To overcome the drawback of kisspep
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14f0c211ceb9c444364d3a61a33d1c77
http://europepmc.org/articles/PMC4887910
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