Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Mathieu Bibian"'
Autor:
Clara Penas, Eve-Ellen Govek, Yin Fang, Vimal Ramachandran, Mark Daniel, Weiping Wang, Marie E. Maloof, Ronald J. Rahaim, Mathieu Bibian, Daisuke Kawauchi, David Finkelstein, Jeng-Liang Han, Jun Long, Bin Li, David J. Robbins, Marcos Malumbres, Martine F. Roussel, William R. Roush, Mary E. Hatten, Nagi G. Ayad
Publikováno v:
Cell Reports, Vol 11, Iss 2, Pp 249-260 (2015)
Although casein kinase 1δ (CK1δ) is at the center of multiple signaling pathways, its role in the expansion of CNS progenitor cells is unknown. Using mouse cerebellar granule cell progenitors (GCPs) as a model for brain neurogenesis, we demonstrate
Externí odkaz:
https://doaj.org/article/2151b5d008f24920a38f942f1ddc596a
Autor:
Annemieke Madder, Bruno Van Mele, James Gardiner, Maria Mercedes Diaz Acevedo, Steven Ballet, Richard Hoogenboom, Jeroen Mangelschots, Lynne J. Waddington, Bruno G. De Geest, Mathieu Bibian
Publikováno v:
Journal of materials chemistry. B. 3(5)
The amphiphilic peptide sequence H-Phe-Glu-Phe-Gln-Phe-Lys-OH (MBG-1) is developed as a novel hydrogelator for use in controlled-drug release administration, which is the smallest tunable ionic self-complementary hydrogelating peptide reported to dat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a1df52788320365b8b6ac5caf8ed7d8
https://pubmed.ncbi.nlm.nih.gov/32262166
https://pubmed.ncbi.nlm.nih.gov/32262166
Autor:
Steven Ballet, Mathieu Bibian, Richard Hoogenboom, Tanila Ben Haddou, Edith Oyen, James Gardiner, Mariana Spetea, Charlotte Martin, Bruno Van Mele, Annemieke Madder, Jessica Andrade, Jeroen Mangelschots
Publikováno v:
MedChemComm. 7:542-549
Herein, a family of hydrogel-forming peptides was designed starting from the short, tunable and amphipathic hexapeptide hydrogelator H-Phe-Glu-Phe-Gln-Phe-Lys-OH (1). The hydrophobic side chains as well as the nature of both N- and C-termini were mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b072715aebf078314fd479cf2e577e2
https://doi.org/10.1039/c5md00440c
https://doi.org/10.1039/c5md00440c
Autor:
Daisuke Kawauchi, William R. Roush, Vimal Ramachandran, Yin Fang, Clara Penas, David Finkelstein, David J. Robbins, Marcos Malumbres, Ronald J. Rahaim, Mary E. Hatten, Weiping Wang, Marie E. Maloof, Bin Li, Jeng Liang Han, Mathieu Bibian, Jun Long, Eve-Ellen Govek, Nagi G. Ayad, Mark Daniel, Martine F. Roussel
Publikováno v:
Repisalud
Instituto de Salud Carlos III (ISCIII)
Cell Reports, Vol 11, Iss 2, Pp 249-260 (2015)
Instituto de Salud Carlos III (ISCIII)
Cell Reports, Vol 11, Iss 2, Pp 249-260 (2015)
Although casein kinase 1δ (CK1δ) is at the center of multiple signaling pathways, its role in the expansion of CNS progenitor cells is unknown. Using mouse cerebellar granule cell progenitors (GCPs) as a model for brain neurogenesis, we demonstrate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfccb85b1d5af51bcc04fd62134e5063
Autor:
Jun-Li Luo, Philip LoGrasso, Yuntao Wu, Yan Yin, Jia Guo, Nibal Eid, Chul Park, Ji-Hak Jeong, Ke Zheng, Yangbo Feng, Fei Yi, Pamela Hernandez, Mathieu Bibian, Weilin Wu, HaJeung Park, Shannon Howard
Publikováno v:
Journal of Medicinal Chemistry. 58:1846-1861
The discovery/optimization of bis-aryl ureas as Limk inhibitors to obtain high potency and selectivity, and appropriate pharmacokinetic properties through systematic SAR studies is reported. Docking studies supported the observed SAR. Optimized Limk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d71d9a9d820ce96e87a550e6007e373a
https://doi.org/10.1021/jm501680m
https://doi.org/10.1021/jm501680m
Autor:
Yongjun Jiang, Hong Shang, Veronica Soloveva, Binhua Ling, Dima N. Gharaibeh, Chul Park, Deemah Dabbagh, John Naughton, Jacque Fontenot, Mathieu Bibian, Xuehua Xu, Ramin M. Hakami, Yan Yin, John A. T. Young, Sijia He, Cary Retterer, HaJeung Park, Margaret L. Pitt, Yuntao Wu, Mark Spear, Ke Zheng, Sina Bavari, Yangbo Feng, Kylene Kehn-Hall, Jia Guo, Rouzbeh Zamani, Fei Yi
Publikováno v:
Journal of Virology
A dynamic actin cytoskeleton is necessary for viral entry, intracellular migration, and virion release. For HIV-1 infection, during entry, the virus triggers early actin activity by hijacking chemokine coreceptor signaling, which activates a host dep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e898b57f02a46d761e6b3ce080ea362
https://doi.org/10.1128/jvi.02418-16
https://doi.org/10.1128/jvi.02418-16
Autor:
Ronald J. Rahaim, Yoshihiko Noguchi, Yangbo Feng, Shima Nakanishi, Lin Li, Konstantin Licht, Laura H. Rosenberg, Weimin Chen, John L. Cleveland, Stephan C. Schürer, William R. Roush, Jun Yong Choi, Michael D. Cameron, Mathieu Bibian, Derek R. Duckett
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 23:4374-4380
The development of a series of potent and highly selective casein kinase 1δ/e (CK1δ/e) inhibitors is described. Starting from a purine scaffold inhibitor (SR-653234) identified by high throughput screening, we developed a series of potent and highl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::605695bf6443d3205752074bd96d5714
https://doi.org/10.1016/j.bmcl.2013.05.075
https://doi.org/10.1016/j.bmcl.2013.05.075
Autor:
Bruno Van Mele, Mathieu Bibian, Maria Mercedes Diaz Acevedo, Richard Hoogenboom, Lynne J. Waddington, Steven Ballet, Ann Van Eeckhaut, Annemieke Madder, Jeroen Mangelschots, James Gardiner, Yannick Van Wanseele
Publikováno v:
Biomacromolecules. 17(2)
Peptide hydrogels are a highly promising class of materials for biomedical application, albeit facing many challenges with regard to stability and tunability. Here, we report a new class of amphipathic peptide hydrogelators, namely mixed α/β-peptid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd44f770c4a8e646cb415a1f14ae2cdf
https://pubmed.ncbi.nlm.nih.gov/26741458
https://pubmed.ncbi.nlm.nih.gov/26741458
Autor:
Laura H. Rosenberg, Marie Lafitte, Victor Quereda, Wayne Grant, Weimin Chen, Mathieu Bibian, Yoshihiko Noguchi, Mohammad Fallahi, Chunying Yang, Jenny C. Chang, William R. Roush, John L. Cleveland, Derek R. Duckett
Publikováno v:
Science Translational Medicine. 7
Identification of specific drivers of human cancer is required to instruct the development of targeted therapeutics. We demonstrate that CSNK1D is amplified and/or overexpressed in human breast tumors and that casein kinase 1δ (CK1δ) is a vulnerabi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb30c689c4be70c73123381a0b5efe53
https://doi.org/10.1126/scitranslmed.aac8773
https://doi.org/10.1126/scitranslmed.aac8773
Publikováno v:
Tetrahedron
Tetrahedron, Elsevier, 2011, 67, pp.7042-7049. ⟨10.1016/j.tet.2011.07.011⟩
Tetrahedron, Elsevier, 2011, 67, pp.7042-7049. ⟨10.1016/j.tet.2011.07.011⟩
International audience; We report on the synthesis of 1,2,4-triazoles substituted with 2 or 3 amino acid side chains, using silver benzoate as a key reagent for the cyclization step. A complete study of the optical purity retention during the synthet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f83bbcb3cee8487ca27f2a8f6ca2abef
https://hal.archives-ouvertes.fr/hal-00617701
https://hal.archives-ouvertes.fr/hal-00617701
