Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Mathieu, Brochet"'
Publikováno v:
mBio, Vol 15, Iss 10 (2024)
ABSTRACT Malaria is a mosquito-borne infectious disease caused by unicellular eukaryotic parasites of the Plasmodium genus. Protein ubiquitination by E3 ligases is a critical post-translational modification required for various cellular processes dur
Externí odkaz:
https://doaj.org/article/15b025f805834b80adc070ba5815288a
Autor:
Mohammad Zeeshan, Edward Rea, Steven Abel, Kruno Vukušić, Robert Markus, Declan Brady, Antonius Eze, Ravish Rashpa, Aurelia C. Balestra, Andrew R. Bottrill, Mathieu Brochet, David S. Guttery, Iva M. Tolić, Anthony A. Holder, Karine G. Le Roch, Eelco C. Tromer, Rita Tewari
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract The Aurora family of kinases orchestrates chromosome segregation and cytokinesis during cell division, with precise spatiotemporal regulation of its catalytic activities by distinct protein scaffolds. Plasmodium spp., the causative agents of
Externí odkaz:
https://doaj.org/article/b48dddf02dd94fbda52d44cd32baa0e1
Publikováno v:
mBio, Vol 15, Iss 2 (2024)
ABSTRACT Apicomplexa encompasses a large number of intracellular parasites infecting a wide range of animals. Cyclic nucleotide signaling is crucial for a variety of apicomplexan life stages and cellular processes. The cyclases and kinases that synth
Externí odkaz:
https://doaj.org/article/db88c2eeeb0c472fb95d9276197b39d8
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Raspha et al. apply proteomics and different microscopy approaches to investigate the role of ubiquitination in the lifecycle progression of Plasmodium berghei. They describe the location and function of proteins linked to the conserved SKP1/Culin1/F
Externí odkaz:
https://doaj.org/article/6a1b3cb8e7f9487b8ac11e869406c39b
Autor:
Christoph Wenz, Caroline Sophie Simon, Tatiany Patricia Romão, Vanessa Saskia Stürmer, Marta Machado, Natacha Klages, Anja Klemmer, Yannik Voß, Markus Ganter, Mathieu Brochet, Julien Guizetti
Publikováno v:
PLoS Pathogens, Vol 19, Iss 5, p e1011325 (2023)
Malaria-causing parasites achieve rapid proliferation in human blood through multiple rounds of asynchronous nuclear division followed by daughter cell formation. Nuclear divisions critically depend on the centriolar plaque, which organizes intranucl
Externí odkaz:
https://doaj.org/article/510d636df35b43d79360a36d0d69a199
Autor:
Mohammad Zeeshan, Ravish Rashpa, David J P Ferguson, Steven Abel, Zeinab Chahine, Declan Brady, Sue Vaughan, Carolyn A Moores, Karine G Le Roch, Mathieu Brochet, Anthony A Holder, Rita Tewari
Publikováno v:
PLoS Biology, Vol 20, Iss 7, p e3001704 (2022)
Kinesins are microtubule (MT)-based motors important in cell division, motility, polarity, and intracellular transport in many eukaryotes. However, they are poorly studied in the divergent eukaryotic pathogens Plasmodium spp., the causative agents of
Externí odkaz:
https://doaj.org/article/c59ab74510044eb5b8416d04d84d4899
Autor:
Mohammad Zeeshan, Rajan Pandey, Amit Kumar Subudhi, David J. P. Ferguson, Gursimran Kaur, Ravish Rashpa, Raushan Nugmanova, Declan Brady, Andrew R. Bottrill, Sue Vaughan, Mathieu Brochet, Mathieu Bollen, Arnab Pain, Anthony A. Holder, David S. Guttery, Rita Tewari
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Zeeshan et al. used real-time live-cell and ultrastructural imaging, conditional gene knockdown, RNA-seq and proteomic approaches to implicate Plasmodium PP1 in both mitotic exit and, potentially, establishing cell polarity during zygote development
Externí odkaz:
https://doaj.org/article/b7773fc630264f8886ca813289e58978
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Abstract In malaria parasites, male gametogenesis is a proliferative stage essential for parasite transmission to the mosquito vector. It is a rapid process involving three rounds of genome replication alternating with closed endomitoses, and assembl
Externí odkaz:
https://doaj.org/article/fb3e8f58565243c88594bb8e0d571e74
Autor:
Ravish Rashpa, Mathieu Brochet
Publikováno v:
PLoS Pathogens, Vol 18, Iss 1, p e1010223 (2022)
Transmission of malaria-causing parasites to mosquitoes relies on the production of gametocyte stages and their development into gametes. These stages display various microtubule cytoskeletons and the architecture of the corresponding microtubule org
Externí odkaz:
https://doaj.org/article/fee594b6b9f847b590d9d3ec3c20ac45
Autor:
Eloïse Bertiaux, Aurélia C Balestra, Lorène Bournonville, Vincent Louvel, Bohumil Maco, Dominique Soldati-Favre, Mathieu Brochet, Paul Guichard, Virginie Hamel
Publikováno v:
PLoS Biology, Vol 19, Iss 9, p e3001401 (2021)
[This corrects the article DOI: 10.1371/journal.pbio.3001020.].
Externí odkaz:
https://doaj.org/article/cc2d9811dd6f4a71b703c3d7d865456f